F1190 Introduction to biophysics

Faculty of Science
autumn 2017
Extent and Intensity
1/1. 2 credit(s) (plus extra credits for completion). Type of Completion: k (colloquium).
Teacher(s)
prof. Dr. Jiří Kozelka, PhD. (lecturer)
doc. Mgr. Karel Kubíček, PhD. (lecturer)
prof. RNDr. Vojtěch Mornstein, CSc. (seminar tutor)
Guaranteed by
prof. RNDr. Josef Humlíček, CSc.
Department of Condensed Matter Physics – Physics Section – Faculty of Science
Contact Person: prof. Dr. Jiří Kozelka, PhD.
Supplier department: Department of Condensed Matter Physics – Physics Section – Faculty of Science
Timetable
Mon 18. 9. to Fri 15. 12. Wed 8:00–8:50 Fs1 6/1017, Wed 9:00–9:50 Fs1 6/1017
Prerequisites
Excellent knowledge of high-school mathematics, physics, and chemistry
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
This course is to give the students the first touch with the central themes of biophysics. Special attention is paid to the principles of physical methods that are used to study the structure of biopolymers. A second main theme are intermolecular forces and their relationship with macroscopic physical and chemical properties. Lectured will be also the physical principles of the interactions between radiation and matter, and the application of these interactions on the structural studies of biopolymers.

After successful passing of this course the students should be able to
- discuss the relationship between constitution and structure of a molecule on one hand and its physical and chemical properties on the other hand
- describe the physical fundaments of the interaction between various forms of radiation and matter and demonstrate its application in spectroscopical methods for molecules structural properties research
- list the basic properties of biopolymers.
Learning outcomes
The student will get acquainted with the structure and basic functions of nucleic acids and proteins, and with the construction and the functions of biomembranes. The student will also learn about the typical problems that biophysical research attempts to solve, and about standard methods that biophysics uses.
Syllabus
  • 1. What is Biophysics? 2. Introduction into Biophysics of radiation 3. Spectroscopic methods for structural studies on biopolymers 4. Introduction into NMR 5. DNA: From the discovery to structure 6. Proteins 7. RNA world 8. Introduction into Molecular modeling 8. Biophysical principles of modern therapeutical methods 9. Microscopes with molecular and atomic resolution 10. Electric phenomena in living organisms 11. Optical spectroscopy and electrophoresis: application to structural studies on biopolymers 12. Metalloenzymes: structure and function 13. Electric and magnetic fields in our environment
Literature
  • KODÍČEK, Milan and Vladimír KARPENKO. Biofysikální chemie. 2. přeprac. a rozš. vyd. Praha: Academia, 2000, 337 s. ISBN 8070802731. info
Teaching methods
lectures, class discussion
Assessment methods
Final colloquium in the form of a written test
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://physics.muni.cz/biophys/vyuka.shtml
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, spring 2012 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.
  • Enrolment Statistics (autumn 2017, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2017/F1190