BVBV0321s Nutritional Biochemistry - seminary

Faculty of Medicine
autumn 2024
Extent and Intensity
0/3/0. 3 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
doc. RNDr. Jiří Dostál, CSc. (assistant)
RNDr. Hana Paulová, CSc. (assistant)
Mgr. Jiří Slanina, Ph.D. (assistant)
prof. RNDr. Eva Táborská, CSc. (assistant)
doc. RNDr. Josef Tomandl, Ph.D. (assistant)
Iva Audy (assistant)
Guaranteed by
Mgr. Marie Tomandlová, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Timetable
Tue 7:20–9:50 B11/327
Prerequisites (in Czech)
BVLC011p Med.Chem.- lecture && BVBC0221p Biochemistry - lect.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course deals with the integration of biochemical processes in the human body. The aim is to understand biochemical processes characteristic of individual tissues and organs and the principles of their regulation, as well as to understand the issue of the influence of nutrition on changes in metabolism in certain diseases/disorders.
Learning outcomes
After completing the course, the student will be able to:
- explain the biochemical nature of nutrient digestion processes, their resorption, and connections with pathological processes;
- characterize the interrelationships between nutrient metabolism under different states of the organism, including pathological ones;
- characterize the metabolic processes of the main organs and tissues and the main disorders;
- discuss the principles of maintaining homeostasis and acid-base balance in the organism;
- explain the principles of metabolic regulation at all levels.
Syllabus
  • • Laboratory tests in clinical biochemistry. Sources of error, assessing the significance of a test result.
  • • Metabolic functions of the gastrointestinal tract.
  • • Glucose in blood (origin, consumption, regulation). Diabetes mellitus. Investigations of glucose metabolism. Disturbances of fructose and galactose metabolism.
  • • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, glutamine and its role in metabolism. Nitrogen balance. The major proteins of blood plasma, function. Enzyme assays in clinical diagnostics.
  • • Plasma lipoproteins, interconversion of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion. Ways affecting the plasmatic level of cholesterol.
  • • Overview of nutrient metabolism in different states.
  • • The liver functions – the role in the metabolism of nutrients, hormones, and vitamins. Hyperbilirubinemia. Biochemical investigations of liver function.
  • • Principles of xenobiotics biotransformation. Metabolism of ethanol. Metabolism of iron and copper.
  • • Principles of neurotransmitter and hormone effects. Types and structures of receptors.
  • • Regulation of metabolism. Metabolism of nervous tissue.
  • • Water and Na+, K+ ions balance, osmolality, and volume of ECF.
  • • Acid-base balance. Parameters of acid-base status.
  • • Biochemical functions of kidneys. Hormones affecting kidney function. Urine. Urinary stones.
  • • Metabolism of calcium, magnesium, phosphates, fluorine, and iodine.
  • • Biochemistry of blood cells.
  • • Vitamines.
Literature
  • Podklady pro semináře v IS.
  • LEDVINA, Miroslav, Alena STOKLASOVÁ and Jaroslav CERMAN. Biochemie pro studující medicíny. 3. vydání. Praha: Univerzita Karlova, nakladatelství Karolinum, 2020, 269 stran. ISBN 9788024647487. info
  • LEDVINA, Miroslav, Alena STOKLASOVÁ and Jaroslav CERMAN. Biochemie pro studující medicíny. 3. vydání. Praha: Univerzita Karlova, nakladatelství Karolinum, 2020, Strana 275. ISBN 9788024647494. info
  • KOOLMAN, Jan and Klaus-Heinrich RÖHM. Barevný atlas biochemie. 1st ed. Praha: Grada, 2012, 498 pp. ISBN 978-80-247-2977-0. info
  • STIPANUK, Martha H. and Marie A. CAUDILL. Biochemical, physiological, and molecular aspects of human nutrition. Fourth Edition. S. Louis: Saunders, 2019, xiv, 959. ISBN 9780323441810. info
Teaching methods
Course has a form seminars and discussions on given issues and topics in seminars.
Assessment methods
Oral examination.
Language of instruction
Czech
Further comments (probably available only in Czech)
Information on the extent and intensity of the course: 45.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/med/autumn2024/BVBV0321s