LF:VLBI0121p Biology I - lect. - Course Information
VLBI0121p Medical Biology I - lecture
Faculty of Medicineautumn 2024
- Extent and Intensity
- 2/0/0. 1 credit(s). Type of Completion: z (credit).
In-person direct teaching - Teacher(s)
- prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
Mgr. Kateřina Francová, Ph.D. (lecturer)
Mgr. Kateřina Straková, Ph.D. (lecturer)
Jana Růžičková (assistant)
Mgr. Anna Dorotíková (seminar tutor)
Ing. Natália Vadovičová (seminar tutor) - Guaranteed by
- prof. RNDr. Ondřej Slabý, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Cetkovská, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine - Timetable
- Wed 18. 9. 14:30–16:10 B22/116 aula, Wed 25. 9. 14:30–16:10 B22/116 aula, Wed 2. 10. 14:30–16:10 B22/116 aula, Wed 9. 10. 14:30–16:10 B22/116 aula, Wed 16. 10. 14:30–15:50 B11/114, Wed 23. 10. 14:30–16:10 B22/116 aula, Wed 30. 10. 14:30–16:10 B22/116 aula, Wed 6. 11. 14:30–16:10 B22/116 aula, Wed 13. 11. 14:30–16:10 B22/116 aula, Wed 20. 11. 14:30–16:10 B22/116 aula, Wed 27. 11. 14:30–16:10 B22/116 aula, Wed 4. 12. 14:30–16:10 B22/116 aula, Wed 18. 12. 14:30–16:10 B22/116 aula
- Prerequisites
- Knowledge of high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_ENG.qwarp) or similar, and knowledge of all previous lectures and practical classes of the subject. Expected knowledge for each lecture is specified in the course syllabus.
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- General Medicine (programme LF, M-VL) (2)
- Course objectives
- The main objectives of the course are:
- understanding of cellular and molecular biology with a special focus on the potential application of acquired knowledge in clinical medicine - Learning outcomes
- After completing the course, the student will be able to:
- describe and explain the organization of the prokaryotic and eukaryotic genome, DNA replication
- explain elementary processes taking place in cells (gene expression, inter- and intra-cellular communication, cell differentiation, cell division, cell death) and their purposes
- explain the relationship between malfunctioning cellular processes and the development of diseases
- explain how gene mutations and chromosome aberrations cause human diseases and illustrate it with examples - Syllabus
- 1. Introduction to the Medical Biology
- 2. Fundamental Chemistry of Life – Chemical Components of Cells, Protein Structure and Function
- 3. Architecture and Function of Eukaryotic Cell – Membrane System, Organelles, Cytoskeletal System
- 4. Genome Organization – Nucleic Acids, Chromosome Structure, DNA replication
- 5. Genome Stability and Instability – DNA damage, Mutations, DNA repair and Defects in DNA repair
- 6. Gene Expression I – Central Dogma of Molecular Biology, Gene Structure, Transcription and RNA modification
- 7. Gene Expression II – Translation, Genetic Code, Post-translational Modifications
- 8. Regulation of Gene Expression
- 9. Cellular Communication – General Principles of Cell Signalling, Receptors, Signalling Pathways
- 10. Cell Division – Mitosis and Meiosis
- 11. Cell Cycle and Principles of its Regulation
- 12. Cell Death
- 13. Cells and Tissue – Cell Junctions, Adhesive Molecules and Extracellular Matrix
- Literature
- required literature
- SLABÝ, Ondřej. Lékařská biologie II. Genetika a molekulární medicína (Medical Biology II. Genetics and molecular medicine). 1st ed. Brno: Masarykova univerzita, 2023, 227 pp. ISBN 978-80-280-0338-8. info
- SLABÝ, Ondřej. Lékařská biologie. 1. vydání. Brno: Masarykova univerzita, 2022, 268 stran. ISBN 9788028000608. info
- Teaching methods
- lecture every week
- Assessment methods
- Without examination - Medical Biology I is continued with Medical Biology II which is completed with an oral exam.
- Language of instruction
- Czech
- Follow-Up Courses
- Further comments (probably available only in Czech)
- Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 30. - Listed among pre-requisites of other courses
- Teacher's information
- https://is.muni.cz/auth/el/med/podzim2024/VLBI0121p/index.qwarp
Lectures take place every week. We recommend following the Interactive syllabus of the course where students can find all relevant information (schedule, substitutions, public holidays etc.), lecture´s presentations, and also links to animations and videos relevant to the topic: https://is.muni.cz/auth/el/med/podzim2024/VLBI0121p/index.qwarp
- Enrolment Statistics (recent)
- Permalink: https://is.muni.cz/course/med/autumn2024/VLBI0121p