VLBI0121p Biology I - lecture

Faculty of Medicine
autumn 2018
Extent and Intensity
1/0/0. 0 credit(s). Type of Completion: z (credit).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
prof. Ing. Petr Dvořák, CSc. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
RNDr. Pavel Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
RNDr. Mário Špírek, PhD. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (seminar tutor)
Mgr. Kateřina Straková, Ph.D. (seminar tutor)
Jana Růžičková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Wed 19. 9. 10:00–10:50 B22/116 aula, Wed 26. 9. 10:00–10:50 B22/116 aula, Wed 3. 10. 10:00–10:50 B22/116 aula, Wed 10. 10. 10:00–10:50 B22/116 aula, Wed 17. 10. 10:00–10:50 B22/116 aula, Wed 24. 10. 10:00–10:50 B22/116 aula, Wed 31. 10. 10:00–10:50 B22/116 aula, Wed 7. 11. 10:00–10:50 B22/116 aula, Wed 14. 11. 10:00–10:50 B22/116 aula, Wed 21. 11. 10:00–10:50 B22/116 aula, Wed 28. 11. 10:00–10:50 B22/116 aula, Wed 5. 12. 10:00–10:50 B22/116 aula, Wed 19. 12. 10:00–10:50 B22/116 aula
Prerequisites
Knowledge of high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_CZ.qwarp) or similar, and knowledge of all previous lectures and practical classes of the subject. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding the elementary cellular processes and the principle of intercellular communication
- understanding the principle of developing bacterial, viral and genetically determined diseases
Learning outcomes
After completing the course the student will be able to:
- explain elementary processes taking place in cells and human body (gene expression, intercellular communication, cell differentiation, cell division, cell death) and their purposes
- express the basic coherence between malfunctioning cellular processes and development of diseases
- explain the general mechanism of pathogenesis in bacterial and viral diseases
- explain the general mechanism of pathogenesis of gene mutations and chromosome aberrations in humans, and illustrate it with examples
- explain the effects of therapies interacting with cellular processes; explain the principles of anti-bacterial, anti-viral and anti-mitotic treatment
Syllabus
  • Introduction to medical biology – from understanding the cellular principle to modern biomedicine
  • Bacteria and viruses – characteristics, reproduction strategies and principles of treatment
  • Structure, functions and function anomalies of eukaryotic cells
  • Cell signalling and the principle of cell differentiation
  • Cells in the context of the entire organism – principles of cell adhesion and intercellular communication
  • The importance of genetic information – the journey from a gene to protein; DNA replication
  • Cell cycle – molecular mechanisms of regulation and significance for oncology
  • Mitotic division in normal and cancer cells
  • Meiosis and the principle of genetic variability
  • The basics of genetics, the nature of dominance and recessivity
  • Genetics of human diseases – molecular principles of genetically determined disorders
  • Cell death – mechanisms and regulation of apoptosis and its significance for medicine
  • Epigenetics – the link between genes and environment
Literature
    required literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • PRITCHARD, D. J. and Bruce R. KORF. Základy lékařské genetiky. první české vydání. Praha: Galén, 2007, 182 stran. ISBN 9788072624492. info
    not specified
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014, xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013, 1 online r. ISBN 9781118689028. info
Teaching methods
lecture every week
Assessment methods
Lecture attendance is optional. Without examination - Biology I is continued with Biology II which is completed with a written examination test based on knowledge of all topics from both semesters (lectures, seminars, practices).
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 15.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/1411/podzim2018/VLBI0121p/index.qwarp
The course is also listed under the following terms Autumn 2015, Autumn 2016, Autumn 2017, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (autumn 2018, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2018/VLBI0121p