ZLFA0621c Pharmacology I - practice

Faculty of Medicine
spring 2025
Extent and Intensity
0/2/0. 2 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
PharmDr. Mária Hricková (seminar tutor)
PharmDr. Eva Klásková (seminar tutor)
MUDr. Alena Máchalová, Ph.D. (seminar tutor)
MUDr. Jana Nováková, Ph.D. (seminar tutor)
doc. PharmDr. Ondřej Zendulka, Ph.D. (seminar tutor)
Renata Bláblová (assistant)
Mgr. Marta Vyoralová (assistant)
doc. RNDr. Ladislava Bartošová, Ph.D. (alternate examiner)
doc. PharmDr. Jan Juřica, Ph.D. (alternate examiner)
Guaranteed by
doc. PharmDr. Ondřej Zendulka, Ph.D.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: doc. PharmDr. Ondřej Zendulka, Ph.D.
Supplier department: Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Timetable of Seminar Groups
ZLFA0621c/21: Fri 21. 2. 13:30–16:00 A16/217, Mon 10. 3. 11:00–13:30 A16/217, Fri 14. 3. 11:00–13:30 A16/217, Fri 21. 3. 13:30–16:00 A16/217, Fri 28. 3. 13:30–16:00 A16/217, Fri 4. 4. 11:00–13:30 A16/217, Fri 11. 4. 13:30–16:00 A16/217, Fri 25. 4. 13:30–16:00 A16/217, Fri 16. 5. 13:30–16:00 A16/217, Fri 30. 5. 13:30–16:00 A16/217, M. Hricková
ZLFA0621c/22: Fri 28. 2. 11:00–13:30 A19/326, Fri 14. 3. 13:30–16:00 A19/326, Mon 17. 3. 11:00–13:30 A16/308, Fri 21. 3. 11:00–13:30 A19/326, Fri 4. 4. 13:30–16:00 A19/326, Fri 11. 4. 13:30–16:00 A19/326, Fri 25. 4. 13:30–16:00 A19/326, Fri 9. 5. 13:30–16:00 A19/326, Fri 16. 5. 13:30–16:00 A19/326, Fri 23. 5. 13:30–16:00 A19/326, A. Máchalová
ZLFA0621c/23: Fri 21. 2. 13:30–16:00 A19/326, Tue 4. 3. 10:45–13:15 A16/217, Fri 7. 3. 13:30–16:00 A16/217, Mon 17. 3. 11:00–13:30 A16/217, Fri 21. 3. 11:00–13:30 A16/217, Mon 24. 3. 11:00–13:30 A16/217, Fri 28. 3. 11:00–13:30 A16/217, Fri 9. 5. 13:30–16:00 A16/217, Fri 23. 5. 13:30–16:00 A16/217, Fri 30. 5. 13:30–16:00 A19/326, O. Zendulka
Prerequisites
ZLPA0521c Pathology I - practice && ZLPF0521c Pathophysiol.I - practice && ZLCP051c Clin. Exam. in Surgery-pract.
The student has completed ZLPA0521c, ZLPF0521c, ZLCP051c courses.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Upon completion of the course, the student will be able to choose the formally correct prescription of drugs using the terminology of the valid pharmacopoeia and the preparation of dosage forms of individually and mass prepared medicinal products. He/she should understand the principles of "pharmacological thinking" in drug selection, dosage, pharmacokinetic parameter calculations, choice and technique of administration routes and should be proficient in the basic pharmacological profile of selected drug groups.
Learning outcomes
Upon completion of the course, the student will:
- be familiar with medicinal product databases and be able to search for specific medicinal products
- distinguish between different routes of administration and dosage forms of a drug and their advantages and disadvantages
- be able to prescribe HVLP and IPLP
- know the basic pharmacokinetic processes and parameters and can determine the type of mechanism of action of specific drugs
- know the basic pharmacological profile of the drug groups discussed
Syllabus

  • Pharmacology - practicals

    Dentistry

    Spring semester 2025

  • 21.2., 28.2.
  • 1. ROUTES OF DRUG ADMINISTRATION, DOSAGE FORMS, SOURCES OF INFORMATION ON MEDICINAL PRODUCTS
  • Preparation for exercise/self-study: Chapter 3 of Selected Chapters of General Pharmacology for General and Dental Medicine students at LF MU. Decree on prescribing LP, selected sections of the Law on Medicines.
  • Lesson content: Organizational information for the study of pharmacology, continuous assessment system, study materials. Classification of application methods: Describe individual application methods with examples of drugs. Video demonstrations of less common routes of administration. Classification and overview of dosage forms for mass production and individual preparation, as well as advantages and disadvantages of different dosage forms in clinical use, typical excipients. Controlled release dosage forms.Working with the SUKL, EMA and AISLP databases, ATC classification. Czech pharmacopoeia.
  • 4.3., 10.3., 14.3.
  • 2. PRESCRIBING OF MEDICINAL PRODUCTS
  • Preparation for exercise/self-study: Practical Calculations in Pharmacology exercise book - recommended to start the Calculations in IPLP Prescribing chapter. Prescribing Terminology.
  • Lesson content: Basics of prescribing RMP and IPP. Prescribing of PPIs in dentistry.
  • 7.3., 14.3., 17.3.
  • 3. PHARMACOKINETICS, PHARMACODYNAMICS
  • Preparation for exercise/self-study: Lecture 2. Chapters 1 and 2 of Selected Chapters in General Pharmacology for General and Dental Medicine Students at LF MU.
  • Lesson content: Mechanisms of drug action - classification, examples. Change in drug effect after repeated administration.Factors influencing the pharmacokinetics of the drug.
  • 17.3., 21.3.
  • TEST MCQ 1
  • 4. THURSDAY INTRODUCTION TO VNS PHARMACOLOGY + PHARMACOLOGY OF PARASYMPATHETIC
  • Preparation for exercise/self-study: Review of lessons 1-3. Record of the 4th lecture, review of VNS physiology.
  • Lesson content: Drugs acting on the parasympathetic nervous system - classification, basic pharmacological characteristics.
  • 21.3., 28.3., 4.4.
  • 5. PHARMACOLOGY OF THE SYMPATHETIC NERVOUS SYSTEM
  • Preparation for exercise/self-study: Record of the 4th lecture.
  • Lesson content: Drugs acting on the sympathetic nervous system - classification, basic pharmacological characteristics.
  • 24.3., 4.4., 11.4.
  • 6. GLUCOCORTICOIDS, DRUGS AFFECTING BONE METABOLISM
  • Preparation for exercise/self-study: Record of the 5th lecture.
  • Lesson content: Basic pharmacological characteristics of glucocorticoids, agents used in the treatment of osteoporosis.
  • 28.3., 11.4., 25.4.
  • TEST MCQ 2
  • 7. H1-ANTIHISTAMINES, DRUGS FOR DISEASES ASSOCIATED WITH BRONCHIAL OBSTRUCTION, DRUGS USED IN COUGH THERAPY
  • Preparation for exercise/self-study: Review of lessons 4-6. Record of 6th lecture. Inhaled dosage forms.
  • Lesson content: A basic pharmacological review of drugs used to treat chronic bronchial obstruction. Drugs used for cough therapy.
  • 25.4., 9.5.
  • 8. DRUGS OF THE GASTROINTESTINAL TRACT
  • PRESCRIPTION TEST
  • Preparation for exercise/self-study: Review of IPP and RMP prescription. Record of 6th lecture.
  • Lesson content: antiemetics, antiulcer agents, hepatoprotective agents, prokinetics, laxatives, antidiarrheals, rectal agents Basic pharmacological characteristics of neurotropic and musculotropic antispasmodics.
  • 16.5., 23.5.
  • 9. DRUGS FOR DIABETES MELLITUS, OBESITY AND DYSLIPIDEMIA.
  • Preparation for exercise/self-study: Recording of lecture 7. Hypolipidemics, antiobesity agents.
  • Lesson content: Review of drug groups of antidiabetic drugs - basic pharmacological characteristics. Combinations of insulins and insulin regimens. Drugs used in dyslipidaemias, antiobesics.
  • 23.5., 30.5.
  • TEST MCQ 3
  • 10. CASE REPORTS, DRUG INTERACTIONS
  • Preparation for exercise/self-study: Review of material covered in lessons 7-9.
  • Lesson content: Classification and review of significant drug interactions including interactions with dietary supplements or food.
  • CREDITS
Literature
    required literature
  • Landa Leoš, Jan Juřica, Kristýna Nosková, Ondřej Zendulka: Vybrané kapitoly z obecné farmakologie pro studenty všeobecného a zubního lékařství na LF MU. Multimediální podpora výuky klinických a zdravotnických oborů: Portál Lékařské fakulty Masarykovy
  • NOVÁKOVÁ, Jana, Barbora ONDRÁČKOVÁ and Alexandra ŠULCOVÁ. Základy receptury léčivých přípravků pro praktická cvičení z farmakologie - obor Zubní lékařství. Brno: Multimediální podpora výuky klinických a zdravotnických oborů: Portál Lékařské fakulty Masarykovy univerzity, 2010, 96 pp. ISSN 1801-6103. URL info
    recommended literature
  • RITTER, James, R. J. FLOWER, Graeme HENDERSON, Yoon Kong LOKE, David J. MACEWAN, Emma S. J. ROBINSON and James FULLERTON. Rang & Dale's pharmacology / James M. Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEvan, Emma Robinson, James Fullerton. Tenth edition. London: Elsevier, 2024, xvii, 850. ISBN 9780323873963. info
  • http://search.ebscohost.com/login.aspx?direct=true&db=nlebk&AN=1160493&lang=cs&site=ehost-live
  • Základy speciální receptury léčivých přípravků, Juřica a kol., 2014, http://portal.med.muni.cz/clanek-611-zaklady-specialni-receptury-lecivych-pripravku.html
  • ŠVIHOVEC, Jan a kol. Farmakologie, Praha: Grada, 2018. ISBN 978-80-247-5558-8. www.grada.cz/farmakologie-(1)-8687
  • Soubor kazuistik z farmakologie, Zendulka a kol., 2016 http://elportal.cz/publikace/kazuistiky-farmakologie
    not specified
  • MARTÍNKOVÁ, Jiřina. Farmakologie pro studenty zdravotnických oborů. 2., zcela přeprac. a doplň. Praha: Grada, 2014. ISBN 9788024713564. info
Teaching methods
In the practicals, the topics discussed are practised as group and individual activities supplemented by the teacher's explanations and discussions. An essential part of the teaching is the students' home preparation for individual lessons and self-study. Students can check their readiness for the lesson by taking the ROPOT before each class.
Assessment methods
Participation in practical exercises is compulsory. One unexcused absence is allowed. There are four tests in total in the practical exercises:

Prescription test (8th exercise)
- contains one IPLP and one HVLP
- the active substance is indicated in the entry for the IPLP and the pharmacotherapeutic group or indication for the HVLP
- for both preparations, the pharmaceutical form and the quantity of the preparation
- rating: pass/fail
- the time limit is 30 minutes
- can be repeated a maximum of twice

Multiple-choice tests (Exercises 4, 7 and 10)
- on knowledge of the material covered
- the test consists of  10 questions with  3 to 5 multiple choice questions
- the number of correct answers is given at the end of the question
- points are awarded for questions answered completely correctly (2 points)
- the limit for passing the test is 10 points
- only one of the tests can be repeated and only once

TEST
In order to pass:
90% attendance at practice
Successful completion of the Prescription Test
Successful completion of three Multiple-choice tests.

Multiple-choice test results count towards the final grade for Pharmacology II (ZLFA0721p)
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses

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Teacher's information
Information for students:

Classes are held in classrooms according to the timetable listed in the IS.

Due to public holidays, some classes will be taught with other topics. The respective seminar groups will be informed of this fact by e-mail well in advance.

The teaching of pharmacology to students of dental medicine is conducted on a two-semester basis.

In the spring semester, the course is completed with credit. See above for credit requirements.

Completion in the autumn semester = rigorous examination, which consists of a pre-test and an oral part.

The oral exam consists of three randomly selected questions from the headings:

1) general pharmacology

2) special pharmacology

3) selected chapters of special pharmacology relevant to ZL students

The results of the multiple-choice test from practicals and pre-exam tests are included in the final grade, see the ZL Continuous Assessment System document in the Study materials.

The course is also listed under the following terms Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024.
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