aVLFA0721c Pharmacology I - practice

Faculty of Medicine
autumn 2019
Extent and Intensity
0/3/0. 1 credit(s). Type of Completion: z (credit).
Teacher(s)
doc. MUDr. Regina Demlová, Ph.D. (seminar tutor)
doc. PharmDr. Jan Juřica, Ph.D. (seminar tutor)
Mgr. Petra Amchová, Ph.D. (seminar tutor)
doc. RNDr. Ladislava Bartošová, Ph.D. (seminar tutor)
Mgr. Jana Kubátová, Ph.D. (seminar tutor)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (seminar tutor)
Mgr. Kristýna Nosková, Ph.D. (seminar tutor)
MUDr. Jana Nováková, Ph.D. (seminar tutor)
MUDr. Jana Pistovčáková, Ph.D. (seminar tutor)
PharmDr. Jitka Rychlíčková, Ph.D. (seminar tutor)
Mgr. Barbora Říhová, Ph.D. (seminar tutor)
PharmDr. Lenka Součková, Ph.D. (seminar tutor)
MUDr. Filip Šiška (seminar tutor)
doc. PharmDr. Ondřej Zendulka, Ph.D. (seminar tutor)
Renata Bláblová (assistant)
Květoslava Sedlářová (assistant)
Mgr. Kateřina Nebeská (alternate examiner)
Guaranteed by
doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: doc. Mgr. MVDr. Leoš Landa, Ph.D.
Supplier department: Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Timetable of Seminar Groups
aVLFA0721c/30: Thu 26. 9. 13:00–15:30 A19/229, Thu 3. 10. 13:00–15:30 A19/229, Thu 10. 10. 13:00–15:30 A19/229, Thu 17. 10. 13:00–15:30 A19/229, Thu 24. 10. 13:00–15:30 A19/229, Thu 31. 10. 13:00–15:30 A19/229, Thu 7. 11. 13:00–15:30 A19/229, Thu 14. 11. 13:00–15:30 A19/229, Thu 21. 11. 13:00–15:30 A19/229, Thu 28. 11. 13:00–15:30 A19/229, Thu 5. 12. 13:00–15:30 A19/229, Thu 12. 12. 13:00–15:30 A19/229, Thu 19. 12. 13:00–15:30 A19/229, Thu 9. 1. 13:00–15:30 A19/229, Thu 16. 1. 13:00–15:30 A19/229, J. Pistovčáková
aVLFA0721c/31: Mon 23. 9. 13:00–15:30 A19/326, Mon 30. 9. 13:00–15:30 A19/326, Mon 7. 10. 13:00–15:30 A19/326, Mon 14. 10. 13:00–15:30 A19/326, Mon 21. 10. 13:00–15:30 A19/326, Mon 4. 11. 13:00–15:30 A19/326, Mon 11. 11. 13:00–15:30 A19/326, Mon 18. 11. 13:00–15:30 A19/326, Mon 25. 11. 13:00–15:30 A19/326, Mon 2. 12. 13:00–15:30 A19/326, Mon 9. 12. 13:00–15:30 A19/326, Mon 16. 12. 13:00–15:30 A19/326, Mon 6. 1. 13:00–15:30 A19/326, Mon 13. 1. 13:00–15:30 A19/326, L. Landa
aVLFA0721c/32: Wed 25. 9. 13:00–15:30 A19/229, Wed 2. 10. 13:00–15:30 A19/229, Wed 9. 10. 13:00–15:30 A19/229, Wed 16. 10. 13:00–15:30 A19/229, Wed 23. 10. 13:00–15:30 A19/229, Wed 30. 10. 13:00–15:30 A19/229, Wed 6. 11. 13:00–15:30 A19/229, Wed 13. 11. 13:00–15:30 A19/229, Wed 20. 11. 13:00–15:30 A19/229, Wed 27. 11. 13:00–15:30 A19/229, Wed 4. 12. 13:00–15:30 A19/229, Wed 11. 12. 13:00–15:30 A19/229, Wed 18. 12. 13:00–15:30 A19/229, Wed 8. 1. 13:00–15:30 A19/229, Wed 15. 1. 13:00–15:30 A19/229, J. Rychlíčková
aVLFA0721c/33: Fri 27. 9. 13:00–15:30 A19/326, Fri 4. 10. 13:00–15:30 A19/326, Fri 11. 10. 13:00–15:30 A19/326, Fri 18. 10. 13:00–15:30 A19/326, Fri 25. 10. 13:00–15:30 A19/326, Fri 1. 11. 13:00–15:30 A19/326, Fri 8. 11. 13:00–15:30 A19/326, Fri 15. 11. 13:00–15:30 A19/326, Fri 22. 11. 13:00–15:30 A19/326, Fri 29. 11. 13:00–15:30 A19/326, Fri 6. 12. 13:00–15:30 A19/326, Fri 13. 12. 13:00–15:30 A19/326, Fri 20. 12. 13:00–15:30 A19/326, Fri 10. 1. 13:00–15:30 A19/326, Fri 17. 1. 13:00–15:30 A19/326, O. Zendulka
aVLFA0721c/34: Tue 24. 9. 13:00–15:30 A19/229, Tue 1. 10. 13:00–15:30 A19/229, Tue 8. 10. 13:00–15:30 A19/229, Tue 15. 10. 13:00–15:30 A19/229, Tue 22. 10. 13:00–15:30 A19/229, Tue 29. 10. 13:00–15:30 A19/229, Tue 5. 11. 13:00–15:30 A19/229, Tue 12. 11. 13:00–15:30 A19/229, Tue 19. 11. 13:00–15:30 A19/229, Tue 26. 11. 13:00–15:30 A19/229, Tue 3. 12. 13:00–15:30 A19/229, Tue 10. 12. 13:00–15:30 A19/229, Tue 17. 12. 13:00–15:30 A19/229, Tue 7. 1. 13:00–15:30 A19/229, Tue 14. 1. 13:00–15:30 A19/229, J. Juřica
aVLFA0721c/35: Mon 23. 9. 13:00–15:30 A19/231, Mon 30. 9. 13:00–15:30 A19/231, Mon 7. 10. 13:00–15:30 A19/231, Mon 14. 10. 13:00–15:30 A19/231, Mon 21. 10. 13:00–15:30 A19/231, Mon 4. 11. 13:00–15:30 A19/231, Mon 11. 11. 13:00–15:30 A19/231, Mon 18. 11. 13:00–15:30 A19/231, Mon 25. 11. 13:00–15:30 A19/231, Mon 2. 12. 13:00–15:30 A19/231, Mon 9. 12. 13:00–15:30 A19/231, Mon 16. 12. 13:00–15:30 A19/231, Mon 6. 1. 13:00–15:30 A19/231, Mon 13. 1. 13:00–15:30 A19/231, L. Landa
Prerequisites (in Czech)
aVLPF0622c Pathological Phys. II - prac. && aVLPA0622c Pathology II - practice
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aims of the course are:
to recognize the basic pharmacological terminology and legislation related to the use of drugs and thei prescription
to understand to differences between single drug dosage forms
to understand to the prescription of drugs
to understand to the basics of pharmacokinetics
to understand to the basic facts about the discussed drugs
Learning outcomes
At the end of the course the student knows:
single pharmacoterapeutical drug classes
single drug dosage forms
the modes of action, adverse reactions and basic indications of single drugs of discussed drugs
how to prescribe selected medical preparation or a drug in particular drug dosage form
Syllabus

  • VLFA07212c - Pharmacology I - practical lessons

    General medicine

    Autumn semester 2019

  • 23. 9. – 27. 9. 2019
  • Topic 1: INFORMATION ON DRUGS
  • Course content: Organisation of practical courses and lectures, system of evaluation. Repetition of basic pharmacologic terminology. Sub-branches of pharmacology. Sources of information concerning drugs and recommended textbooks. Work with relevant databases (Brevíř, SÚKL, EMA, AISLP), ATC classification.
  • Self-studying preparation for practical lessons: Materials for the Lecture No. 1, exam question outlines.
  • 30. 9. – 4. 10. 2019
  • Topic 2: PRESCRIPTION OF MEDICAL PRODUCTS I
  • Course content: General rules of drug prescription. Prescription of the ready-made preparations, drug dosage forms.
  • Self-studying preparation for practical lessons: Materials for the Lecture No. 2. Exam question outlines. Drug dosage forms from the textbook. Legislation of the Czech Republic related to drugs and their prescription (selected section of the Act No. 378/2007 Coll., on Pharmaceuticals and on Amendments to Some Related Acts).
  • 7. 10. – 11. 10. 2019
  • Topic 3: PRESCRIPTION OF MEDICAL PRODUCTS II, ROUTES OF DRUG ADMINISTRATION
  • Course content: Brief characteristics of the individual drug dosage forms. Clinical significance of the way of drug administration.
  • Self-studying preparation for practical lessons: Materials for the Lecture No. 3. Exam question outlines. Information in drug databases - SÚKL (www.sukl.cz), EMA and Drugs.com.
  • 14. 10. – 18 .10. 2019
  • Topic 4: PRINCIPLES OF PHARMACOKINETICS
  • Course content: Pharmacokinetic processes, parameters and calculations.
  • Self-studying preparation for practical lessons: Materials for the Lecture No. 4. Exam Qustion outlines.
  • 21. 10. – 25. 10. 2019
  • Topic 5: PRINCIPLES OF APPLIED PHARMACOKINETICS
  • Course content: Pharmacokinetic case reports, simulation of plasma concentrations course, dosage optimalization and use of software tools, factors affecting course and value of drug´s plasma concentrations.
  • Self-studying preparation for practical lessons: Materials for the Lectures No. 4 and 5.Exam question outlines.
  • 28. 10. – 1. 11. 2019
  • Topic 6: PHARMACODYNAMICS
  • MULTIPLE-CHOICE TEST 1 (Topics 1-5).
  • Course content: Mechanisms of drug effects - classification, examples. Dose-response curves.
  • Self-studying preparation for practical lessons: Materials for the Lecture No. 6.Exam question outlines.
  • 4. 11. – 8. 11. 2019
  • Topic 7: PHARMACOVIGILANCE, ADVERSE DRUG REACTIONS
  • Course content: Classification and characteristics of adverse drug effects. Pharmacovigilance in clinical practice, sources of current information on drug safety.
  • Self-studying preparation for practical lessons: Materials for the Lecture No. 7. Exam question outlines.
  • 11. 11. – 15. 11. 2019
  • Topic 8: FACTORS AFFECTING DRUG EFFECTS
  • Course content: Pharmacotherapy in childhood, in pregnancy, in breastfeeding women, in elderly. Beer's list, STOPP _ START, FORTA, PRRL. Pharmacogenetics.
  • Self-studying preparation for practical lessons: Materials for the Lecture No. 8. Exam question outlines. Pharmacogenetics - materials in IS.
  • 18. 11. – 22. 11. 2019
  • Topic 9: PHARMACOLOGY OF SYMPATHETIC NERVOUS SYSTEM
  • Course content: Drugs affecting sympathetic nervous system - classification, basic pharmacological characteristics.
  • Self-studying preparation for practical lessons: Materials for the Lecture No. 9. Exam question outlines. Pathophysiological bases - ANS, neurotransmitters (their synthesis and degradation), receptors of the sympathetic nervous system (alpha, beta) and parasympathetic nervous system (nicotinic, muscarinic) and their subtypes and organ distribution. Systems of second messengers. Pharmacodynamics, both direct and indirect mechanisms of action.
  • 25. 11. – 29. 11. 2019
  • Topic 10: PHARMACOLOGY OF PARASYMPATHETIC NERVOUS SYSTEM
  • Course content: Drugs affecting parasympathetic nervous system - classification, basic pharmacological characteristics. Spasmolytic drugs.
  • Self-studying preparation for practical lessons: Materials for the Lectures No. 9. Spasmolytic drugs. Exam questions outlines.
  • 2. 12. – 6. 12. 2019
  • Topic 11: ANALGESICS
  • MULTIPLE-CHOICE TEST 2 (Topics 6-10).
  • Course content: MULTIPLE-CHOICE TEST (6th - 10th week). Basic pharmacological characteristics of opioid and non-opioid analgesic drugs, antirheumatoid drugs and drugs used in gout.
  • Self-studying preparation for practical lessons: Materials for the Lectures No. 10 and 11, Exam question outlines. Antirheumatics and anti-gout medications - study material in IS.
  • 9. 12. – 13. 12. 2019
  • Topic 12: ANAESTHETIC DRUGS
  • PRESCRIPTION TEST
  • Course content: Basic pharmacological characteristics of general and local anaesthetic drugs. Premedication prior to general anaesthesia.
  • Self-studying preparation for practical lessons: Materials for the Lecture No. 12. Exam question outlines. Muscle relaxants (IS).
  • 16. 12. – 20. 12. 2019
  • Topic 13: PHARMACOTHERAPY OF DIABETES MELLITUS
  • Course content: Repetition of anti-diabetic drugs - basic pharmacological characteristics. Drugs used in therapy of specific and acute conditions in diabetology. Combinations of insulins, insulin regimens.
  • Self-studying preparation for practical lessons: Materials for the Lecture No. 13. Exam question outlines.
  • 6. 1. – 10. 1. 2020
  • Topic 14: SEX HORMONES
  • Course content: Endocrine therapy, hormone replacement therapy, hormonal contraceptive drugs.
  • Self-studying preparation for practical lessons: Materials for the seminar No. 14. Exam question outlines.Uterotonics and tocolytics.
  • 13. 1. – 17. 1. 2020
  • Topic 15: GLUCOCORTICOIDS, THYROID HORMONES
  • MULTIPLE-CHOICE TEST 3 (Topics 11-14).
  • Course content: Repetition of basic pharmacological characteristics of glucocorticoids and thyroid hormones.
  • Self-studying preparation for practical lessons: Materials for the Lecture No. 15. Exam question outlines.
Literature
    required literature
  • Practicals in Pharmacology, 2009, Náhradní obsah: http://portal.med.muni.cz/article-491-practicals-in-pharmacology.html
  • http://search.ebscohost.com/login.aspx?direct=true&db=nlebk&AN=1160493&lang=cs&site=ehost-live
  • RANG, H. P., James RITTER, R. J. FLOWER and Graeme HENDERSON. Rang & Dale's pharmacology. Eighth edition. [Edinburgh]: Churchill Livingstone, 2016, xv, 760. ISBN 9780702053627. info
    recommended literature
  • WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015, xi, 664. ISBN 9781451191776. info
    not specified
  • Pharmaceutical practice. Edited by Judith A. Rees - Ian Smith - Jennie Watson. 5th ed. Edinburgh: Churchill Livingstone Elsevier, 2014, xvii, 552. ISBN 9780702051432. info
  • Waller, Derek - Renwick, Andrew G. - Hillier, Keith. Medical pharmacology and therapeutics. 3rd ed. New York : Elsevier Saunders, 2009. ix, 744 p. ISBN 0-7020-2991-2.
  • Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8
  • LÜLLMANN, Heinz, Lutz HEIN and Klaus MOHR. Color atlas of pharmacology. Translated by Detlef Bierger, Illustrated by Jürgen Wirth. 4th ed. Stuttgart: Thieme, 2011, x, 393. ISBN 9783137817048. info
  • Pharmacology. Edited by Michelle Alexia Clark. 5th ed. Baltimore: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2012, xii, 612. ISBN 9781451113143. info
Bookmarks
https://is.muni.cz/ln/tag/LF:aVLFA0721c!
Teaching methods
practicals, class discussion

Only 1 absence from practical lessons is possible.
Assessment methods
3 continuous multiple-choice tests (time limit: 15 min) and 1 prescription test in a paper form. MCQ tests will not be repeated. The prescription test can be repeated only twice.

Each multiple-choice test contains 15 questions. The number of correct answers is given. Student gets 1 point for each completely correct answer, i.e. maximum 15 points for each multiple-choice test; total 45 points for all three MCQ tests.

The prescription test consists of two read-made preparations. For both preparations, the active substance, the drug dosage form and the number of original packages to be prescribed will be listed. The prescription handbook will be available for the test.

To obtain credits, the student has to pass the prescription test successfully and also get at least 6 points from each single multiple-choice test and at least 20 points (minimum) from all three MCQ tests.

Note: Together with the new accreditation of the Pharmacology subject for students of General Medicine, a system of continuous assessment of the student was introduced, when the results achieved in multiple-choice tests in practical lessons and colloquium will be taken into account and included in the final mark from the subject.
Language of instruction
English
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 45.
The course is also listed under the following terms Autumn 2017, autumn 2018, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (autumn 2019, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2019/aVLFA0721c