aVLFA0721c Pharmacology I - practice

Faculty of Medicine
autumn 2022
Extent and Intensity
0/3/0. 1 credit(s). Type of Completion: z (credit).
Teacher(s)
doc. MUDr. Regina Demlová, Ph.D. (seminar tutor)
doc. PharmDr. Jan Juřica, Ph.D. (seminar tutor)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (lecturer)
Mgr. Petra Amchová, Ph.D. (seminar tutor)
doc. RNDr. Ladislava Bartošová, Ph.D. (seminar tutor)
MVDr. Eva Dražanová, Ph.D. (seminar tutor)
Mgr. Petr John (seminar tutor)
Mgr. Jana Kubátová, Ph.D. (seminar tutor)
MUDr. Alena Máchalová, Ph.D. (seminar tutor)
Mgr. Kristýna Nosková, Ph.D. (seminar tutor)
MUDr. Jana Nováková, Ph.D. (seminar tutor)
MUDr. Jana Pistovčáková, Ph.D. (seminar tutor)
PharmDr. Jitka Rychlíčková, Ph.D. (seminar tutor)
Mgr. Barbora Říhová, Ph.D. (seminar tutor)
PharmDr. Lenka Součková, Ph.D. (seminar tutor)
doc. PharmDr. Ondřej Zendulka, Ph.D. (seminar tutor)
Guaranteed by
doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: doc. Mgr. MVDr. Leoš Landa, Ph.D.
Supplier department: Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Timetable of Seminar Groups
aVLFA0721c/30: Mon 19. 9. 13:30–16:00 A19/229, Mon 26. 9. 13:30–16:00 A19/229, Mon 3. 10. 13:30–16:00 A19/229, Mon 10. 10. 13:30–16:00 A19/229, Mon 17. 10. 13:30–16:00 A19/229, Mon 24. 10. 13:30–16:00 A19/229, Mon 31. 10. 13:30–16:00 A19/229, Mon 7. 11. 13:30–16:00 A19/229, Mon 14. 11. 13:30–16:00 A19/229, Mon 21. 11. 13:30–16:00 A19/229, Mon 28. 11. 13:30–16:00 A19/229, Mon 5. 12. 13:30–16:00 A19/229, Mon 12. 12. 13:30–16:00 A19/229, Mon 19. 12. 13:30–16:00 A19/229, Mon 2. 1. 13:30–16:00 A19/229, L. Landa
aVLFA0721c/31: Thu 22. 9. 16:00–18:30 A19/229, Thu 29. 9. 16:00–18:30 A19/229, Thu 6. 10. 16:00–18:30 A19/229, Thu 13. 10. 16:00–18:30 A19/229, Thu 20. 10. 16:00–18:30 A19/229, Thu 27. 10. 16:00–18:30 A19/229, Thu 3. 11. 16:00–18:30 A19/229, Thu 10. 11. 16:00–18:30 A19/229, Thu 24. 11. 16:00–18:30 A19/229, Thu 1. 12. 16:00–18:30 A19/229, Thu 8. 12. 16:00–18:30 A19/229, Thu 15. 12. 16:00–18:30 A19/229, Thu 22. 12. 16:00–18:30 A19/229, Thu 5. 1. 10:00–12:30 A19/229, L. Součková
aVLFA0721c/32: Tue 20. 9. 13:30–16:00 A19/229, Tue 27. 9. 13:30–16:00 A19/229, Tue 4. 10. 13:30–16:00 A19/229, Tue 11. 10. 13:30–16:00 A19/229, Tue 18. 10. 13:30–16:00 A19/229, Tue 25. 10. 13:30–16:00 A19/229, Tue 1. 11. 13:30–16:00 A19/229, Tue 8. 11. 13:30–16:00 A19/229, Tue 15. 11. 13:30–16:00 A19/229, Tue 22. 11. 13:30–16:00 A19/229, Tue 29. 11. 13:30–16:00 A19/229, Tue 6. 12. 13:30–16:00 A19/229, Tue 13. 12. 13:30–16:00 A19/229, Tue 20. 12. 13:30–16:00 A19/229, Tue 3. 1. 13:30–16:00 A19/229, J. Pistovčáková
aVLFA0721c/33: Thu 22. 9. 16:00–18:30 A19/326, Thu 29. 9. 16:00–18:30 A19/326, Thu 6. 10. 16:00–18:30 A19/326, Thu 13. 10. 16:00–18:30 A19/326, Thu 20. 10. 16:00–18:30 A19/326, Thu 27. 10. 16:00–18:30 A19/326, Thu 3. 11. 16:00–18:30 A19/326, Thu 10. 11. 16:00–18:30 A19/326, Thu 24. 11. 16:00–18:30 A19/326, Thu 1. 12. 16:00–18:30 A19/326, Thu 8. 12. 16:00–18:30 A19/326, Thu 15. 12. 16:00–18:30 A19/326, Thu 22. 12. 16:00–18:30 A19/326, Thu 5. 1. 16:00–18:30 A19/326, J. Juřica
aVLFA0721c/34: Mon 19. 9. to Mon 19. 12. Mon 16:00–18:30 A19/326; and Mon 2. 1. 16:00–18:30 A19/326, O. Zendulka
aVLFA0721c/35: Thu 22. 9. 16:00–18:30 A19/231, Thu 29. 9. 16:00–18:30 A19/231, Thu 6. 10. 16:00–18:30 A19/231, Thu 13. 10. 16:00–18:30 A19/231, Thu 20. 10. 16:00–18:30 A19/231, Thu 27. 10. 16:00–18:30 A19/231, Thu 3. 11. 16:00–18:30 A19/231, Thu 10. 11. 16:00–18:30 A19/231, Thu 24. 11. 16:00–18:30 A19/231, Thu 1. 12. 16:00–18:30 A19/231, Thu 8. 12. 16:00–18:30 A19/231, Thu 15. 12. 16:00–18:30 A19/231, Thu 22. 12. 16:00–18:30 A19/231, Thu 5. 1. 16:00–18:30 A19/231, J. Rychlíčková
Prerequisites (in Czech)
aVLPF0622p Pathophysiology II - lecture && aVLPA0622c Pathology II - practice
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aims of the course are:
to recognize the basic pharmacological terminology and legislation related to the use of drugs and thei prescription
to understand to differences between single drug dosage forms
to understand to the prescription of drugs
to understand to the basics of pharmacokinetics
to understand to the basic facts about the discussed drugs
Learning outcomes
At the end of the course the student knows:
single pharmacoterapeutical drug classes
single drug dosage forms
the modes of action, adverse reactions and basic indications of single drugs of discussed drugs
how to prescribe selected medical preparation or a drug in particular drug dosage form
Syllabus

  • aVLFA0721c - Pharmacology I - practical lessons

    General medicine

    Autumn semester 2022

  • 19. 9. – 23. 9. 2022
  • Topic 1: INFORMATION ON DRUGS
  • Organisation of practical courses and lectures, our system of evaluation. Repetition of basic pharmacologic terminology. Sub-branches of pharmacology. Sources of information concerning drugs and recommended textbooks. Work with relevant databases (Brevíř, SÚKL, EMA, AISLP), and ATC classification.
  • 26. 9. – 30. 9. 2022
  • Topic 2: ROUTES OF DRUG ADMINISTRATION, DRUG DOSAGE FORMS
  • Brief characteristics of the individual drug dosage forms. Clinical significance of the way of drug administration. Overview of the drug dosage forms.
  • 3. 10. – 7. 10. 2022
  • Topic 3: PRESCRIPTION OF MEDICINAL PRODUCTS
  • General rules of drug prescription. Prescription of the ready-made preparations.
  • 10. 10. – 14.10. 2022
  • Topic 4: PHARMACOKINETICS I
  • Pharmacokinetic processes, parameters and calculations.
  • 17. 10. – 21. 10. 2022
  • Topic 5: PHARMACOKINETICS II
  • Pharmacokinetic case reports, simulation of plasma concentrations course, dosage optimization and use of software tools, factors affecting course and value of drug´s plasma concentrations.
  • 24. 10. – 27. 10. 2022
  • Topic 6: PHARMACODYNAMICS
  • MULTIPLE-CHOICE TEST 1 (Topics 1-5).
  • Mechanisms of drug effects - classification, examples. Dose-response curves.
  • 31. 10. – 4. 11. 2022
  • Topic 7: FACTORS AFFECTING DRUG EFFECTS
  • Pharmacotherapy in childhood, in pregnancy, in breastfeeding women, in the elderly. Beer's list, STOPP-START, FORTA.
  • 7. 11. – 11. 11. 2022
  • Topic 8: PHARMACOVIGILANCE, ADVERSE DRUG REACTIONS
  • PRESCRIPTION TEST
  • Classification and characteristics of adverse drug effects. Pharmacovigilance in clinical practice, sources of information on drug safety.
  • 14. 11. – 18. 11. 2022
  • Topic 9: PHARMACOLOGY OF SYMPATHETIC NERVOUS SYSTEM
  • Receptors of the sympathetic nervous system (alpha, beta) and their subtypes and organ distribution. Classification and basic pharmacological characteristics of drugs influencing the sympathetic nervous system (pharmacodynamics - both direct and indirect mechanisms of drug action, systems of second messengers).
  • 21. 11. – 25. 11. 2022
  • Topic 10: PHARMACOLOGY OF PARASYMPATHETIC NERVOUS SYSTEM, SPASMOLYTIC DRUGS, MUSCLE RELAXANTS
  • Drugs affecting the parasympathetic nervous system - classification, basic pharmacological characteristics. Spasmolytic drugs.
  • 28. 11. – 2. 12. 2022
  • Topic 11: ANALGESICS, PHARMACOTHERAPY OF GOUT
  • Basic pharmacological characteristics of opioid and non-opioid analgesic drugs, antirheumatoid drugs and drugs used in gout.
  • 5. 12. – 9. 12. 2022
  • Topic 12: GLUCOCORTICOIDS, THYROID HORMONES
  • MULTIPLE-CHOICE TEST 2 (Topics 6-10).
  • Repetition of basic pharmacological characteristics of glucocorticoids and thyroid hormones.
  • 12. 12. – 16. 12. 2022
  • Topic 13: H1-ANTIHISTAMINES, THERAPY OF DISEASES WITH BRONCHIAL OBSTRUCTION, THERAPY OF COUGH
  • H1-antihistamines, drugs used for therapy of diseases with bronchial obstruction, inhalation drug dosage forms. Drugs used for the therapy of cough.
  • 19. 12. – 23. 12. 2022
  • Topic 14: PHARMACOTHERAPY OF DIABETES MELLITUS
  • Anti-diabetic drugs - basic pharmacological characteristics. Drugs used in the therapy of specific and acute conditions in diabetology. Combinations of insulins, insulin regimens.
  • 2. 1. – 6. 1. 2023
  • Topic 15: SEX HORMONES
  • MULTIPLE-CHOICE TEST 3 (Topics 11-14).
  • Endocrine therapy, hormone replacement therapy, hormonal contraceptive drugs. Uterotonics and tocolytics. Hormones of HPA axis.
Literature
    required literature
  • Practicals in Pharmacology, 2009, Náhradní obsah: http://portal.med.muni.cz/article-491-practicals-in-pharmacology.html
  • RITTER, James, R. J. FLOWER, Graeme HENDERSON, Yoon Kong LOKE, David J. MACEWAN and H. P. RANG. Rang and Dale's pharmacology. Ninth edition. Edinburgh: Elsevier, 2020, xvi, 789. ISBN 9780702074486. info
  • http://search.ebscohost.com/login.aspx?direct=true&db=nlebk&AN=1160493&lang=cs&site=ehost-live
    not specified
  • Pharmaceutical practice. Edited by Judith A. Rees - Ian Smith - Jennie Watson. 5th ed. Edinburgh: Churchill Livingstone Elsevier, 2014, xvii, 552. ISBN 9780702051432. info
  • Waller, Derek - Renwick, Andrew G. - Hillier, Keith. Medical pharmacology and therapeutics. 3rd ed. New York : Elsevier Saunders, 2009. ix, 744 p. ISBN 0-7020-2991-2.
  • Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8
  • Pharmacology. Edited by Michelle Alexia Clark. 5th ed. Baltimore: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2012, xii, 612. ISBN 9781451113143. info
  • LÜLLMANN, Heinz, Lutz HEIN and Klaus MOHR. Color atlas of pharmacology. Translated by Detlef Bierger, Illustrated by Jürgen Wirth. 4th ed. Stuttgart: Thieme, 2011, x, 393. ISBN 9783137817048. info
Bookmarks
https://is.muni.cz/ln/tag/LF:aVLFA0721c!
Teaching methods
Classes take place periodically in the afternoon. The lectures are followed by practical exercises with discussion.

The lectures discuss the basic issues of the subject. This knowledge is further deepened via specific practical tasks in exercises.

Materials for self-study and preparation for exercises will be available in the interactive syllabus/study materials for each topic, including references to the relevant chapters in the textbook.

2 absences from practical lessons are possible.
Assessment methods
3 continuous multiple-choice tests (time limit: 15 min) and 1 prescription test in a paper form. MCQ tests will not be repeated. The prescription test can be repeated only twice.

Each multiple-choice test contains 15 questions. The number of correct answers is given. Student gets 1 point for each completely correct answer, i.e. maximum 15 points for each multiple-choice test; total 45 points for all three MCQ tests.

The prescription test consists of two read-made preparations. For both preparations, the active substance, the drug dosage form and the number of original packages to be prescribed will be listed. The prescription handbook will be available for the test.

To obtain credits, the student has to pass the prescription test successfully and also get at least 6 points from each single multiple-choice test and at least 20 points (minimum) from all three MCQ tests.

Note: Together with the new accreditation of the Pharmacology subject for students of General Medicine, a system of continuous assessment of the student was introduced, when the results achieved in multiple-choice tests in practical lessons and colloquium will be taken into account and included in the final mark from the subject.
Language of instruction
English
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 45.
The course is also listed under the following terms Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2023, autumn 2024.
  • Enrolment Statistics (autumn 2022, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2022/aVLFA0721c