aVLFA0721p Pharmacology I - lecture

Faculty of Medicine
autumn 2019
Extent and Intensity
2/0/0. 2 credit(s). Type of Completion: k (colloquium).
Teacher(s)
doc. MUDr. Regina Demlová, Ph.D. (lecturer)
doc. PharmDr. Jan Juřica, Ph.D. (lecturer)
Mgr. Petra Amchová, Ph.D. (lecturer)
doc. RNDr. Ladislava Bartošová, Ph.D. (lecturer)
MUDr. Lea Janáková, Ph.D. (lecturer)
Mgr. Jana Kubátová, Ph.D. (lecturer)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (lecturer)
Mgr. Kristýna Nosková, Ph.D. (lecturer)
MUDr. Jana Nováková, Ph.D. (lecturer)
MUDr. Jana Pistovčáková, Ph.D. (lecturer)
doc. PharmDr. Jana Rudá, Ph.D. (lecturer)
PharmDr. Jitka Rychlíčková, Ph.D. (lecturer)
Mgr. Barbora Říhová, Ph.D. (lecturer)
prof. MUDr. Dalibor Valík, Ph.D., DABCC (lecturer)
prof. RNDr. Lenka Zdražilová Dubská, Ph.D. (lecturer)
doc. PharmDr. Ondřej Zendulka, Ph.D. (lecturer)
Renata Bláblová (assistant)
Mgr. Martin Brož (alternate examiner)
PharmDr. Eva Klásková (alternate examiner)
Mgr. Kateřina Nebeská (alternate examiner)
Květoslava Sedlářová (alternate examiner)
Guaranteed by
doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Timetable
Tue 17. 9. 18:00–19:40 B11/114, Tue 24. 9. 18:00–19:40 B11/114, Tue 1. 10. 18:00–19:40 B11/114, Tue 8. 10. 18:00–19:40 B11/114, Tue 15. 10. 17:30–19:10 343, Tue 22. 10. 17:30–19:10 343, Tue 29. 10. 17:30–19:10 343, Tue 5. 11. 17:30–19:10 343, Tue 12. 11. 17:30–19:10 343, Tue 19. 11. 17:30–19:10 343, Tue 26. 11. 17:30–19:10 343, Tue 3. 12. 17:30–19:10 343, Tue 10. 12. 17:30–19:10 343, Tue 17. 12. 17:30–19:10 343, Tue 24. 12. 17:30–19:10 343, Tue 31. 12. 17:30–19:10 343, Tue 7. 1. 17:30–19:10 343
Prerequisites (in Czech)
aVLPF0622c Pathological Phys. II - prac. && aVLPA0622c Pathology II - practice
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aims of the course are:
to explain the basic pharmacodynamic and pharmacokinetic processes and principles
to explain the basic principles of therapy of intoxications
to describe the factors that influence the drug effect
Learning outcomes
Student after the course:
knows basic pharmacodynamic principles
knowns basic pharmacokinetic principles
knows basic factors that influence the effect of drugs
is able to suggest therapeutic measures in case of drug intoxication
Syllabus

  • aVLFA0721p - Pharmacology I - Lectures

    General medicine

    Autumn semester 2019

  • 17. 9. 2019 18:00-19:40, UKB A11/114
  • PHARMACOLOGY AND ITS SUB-BRANCHES
  • Course content: Definition of pharmacology and its sub-branches of pharmacology. Drug, medical product – basic pharmacological terminology. Sources of research and development of new drugs. Principles of correct drug use – types of pharmacotherapy and rational pharmacotherapy.
  • 24. 9. 2019 18:00-19:40, UKB A11/114
  • OVERVIEW OF DRUG DOSAGE FORMS
  • Course content: Classification and overview of drug dosage forms for ready-made production and individual preparation, advantages and disadvantages of the particular types of drug dosage forms in clinical use, typical auxiliary substances (excipients). Drug dosage forms with controlled release.
  • 1. 10. 2019 18:00-19:40, UKB A11/114
  • ROUTES OF DRUG ADMINISTRATION
  • Course content: Classification of routes of administration, description of the individual ways with examples of drugs. Overview of innovative administration routes.
  • 8. 10. 2019 18:00-19:40, UKB A11/114
  • PHARMACOKINETICS I
  • Course content: General principles of drug's fate in the organism. Overview of the basic pharmacokinetic processes and parameters.
  • 15. 10. 2019 18:00-19:40, UKB A11/114
  • PHARMACOKINETICS II
  • Course content: Single, continual and repeated drug administration. Principles of therapeutic drug monitoring. Compartment models. Fundamentals of population pharmacokinetics.
  • 22. 10. 2019 18:00-19:40, UKB A11/114
  • PHARMACODYNAMICS
  • Course content: Mechanisms of drugs effects – classification, examples. Receptor theory – types of ligands and receptors. Change in drug effect after repeated administration.
  • 29. 10. 2019 18:00-19:40, UKB A11/114
  • PHARMACOVIGILANCE AND DRUG'S SAFETY
  • Course content: Adverse effects of drugs - classification and characteristics. Pharmacovigilance in clinical research and practice. Therapeutic index, therapeutic range. Drug anamnesis, polypharmacy and introduction to drug interactions.
  • 5. 11. 2019 18:00-19:40, UKB A11/114
  • FACTORS AFFECTING DRUG'S EFFECTS
  • Course content: Classification, overview and examples of factors affecting drug effects. Fundamentals of pharmacogenetics.
  • 12. 11. 2019 18:00-19:40, UKB A11/114
  • PHARMACOLOGY OF AUTONOMIC NERVOUS SYSTEM
  • Course content: Overview of pharmacology of sympathetic and parasympathetic nervous system – neurotransmission, receptors. Basic indications of substances affecting ANS.
  • 19. 11. 2019 18:00-19:40, UKB A11/114
  • BASIC PRINCIPLES OF BIOLOGICAL THERAPY, BIOLOGICAL THERAPY OF RHEUMATOID AND GOUTY ARTHRITIS
  • Course content: Definition of terms, advantages and disadvantages of biological treatment in comparison to conventional therapy. Fundamental principles of technologies used in production of biological medical products, their classification and examples of clinical use. Overview of biological drugs used in rheumatoid and gouty arthritis.
  • 26. 11. 2019 18:00-19:40, UKB A11/114
  • ANALGESIC DRUGS
  • Course content: Classification of analgesic drugs. Basic pharmacological characteristics and examples of use of opioid analgesics, non-steroidal anti-inflammatory drugs and analgesic-antipyretic drugs.
  • 3. 12. 2019 18:00-19:40, UKB A11/114
  • GENERAL AND LOCAL ANAESTHETIC AGENTS
  • Course content: Classification and pharmacological characteristics of general and local anaesthetic drugs.
  • 10. 12. 2019 18:00-19:40, UKB A11/114
  • PHARMACOTHERAPY OF DIABETES MELLITUS
  • Course content: Insulins and anti-diabetic drugs – classification and basic pharmacological characteristics.
  • 17. 12. 2019 18:00-19:40, UKB A11/114
  • PHARMACOLOGY OF SEX HORMONES
  • Course content: Analogues and antagonists FSH, LH. Oestrogens, antioestrogens, gestagens, antigestagens, androgens, antiandrogens basic pharmacological characteristics (classification, basic substances, therapeutic indications/contraindications, adverse effects).
  • 7. 1. 2020 18:00-19:40, UKB A11/114
  • IMMUNOPHARMACOLOGY - IMMUNOSUPPRESSANTS AND IMMUNOMODULATORS, BIOLOGICS
  • Course content: Overview of drugs affecting immune system - classification, therapeutic use, basic pharmacological characteristics.
Literature
    required literature
  • Practicals in Pharmacology, 2009, Náhradní obsah: http://portal.med.muni.cz/article-491-practicals-in-pharmacology.html
  • http://search.ebscohost.com/login.aspx?direct=true&db=nlebk&AN=1160493&lang=cs&site=ehost-live
  • RANG, H. P., James RITTER, R. J. FLOWER and Graeme HENDERSON. Rang & Dale's pharmacology. Eighth edition. [Edinburgh]: Churchill Livingstone, 2016, xv, 760. ISBN 9780702053627. info
    recommended literature
  • Pharmaceutical practice. Edited by Judith A. Rees - Ian Smith - Jennie Watson. 5th ed. Edinburgh: Churchill Livingstone Elsevier, 2014, xvii, 552. ISBN 9780702051432. info
  • WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015, xi, 664. ISBN 9781451191776. info
    not specified
  • Waller, Derek - Renwick, Andrew G. - Hillier, Keith. Medical pharmacology and therapeutics. 3rd ed. New York : Elsevier Saunders, 2009. ix, 744 p. ISBN 0-7020-2991-2.
  • Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8
  • Pharmacology. Edited by Michelle Alexia Clark. 5th ed. Baltimore: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2012, xii, 612. ISBN 9781451113143. info
Bookmarks
https://is.muni.cz/ln/tag/LF:aVLFA0721p!
Teaching methods
lectures, presentations by professionals in the sectors
Assessment methods
Colloquium - ROPOT test - 40 multiple-choice questions with 3 - 5 answer options. The number of correct answers is given.

Student gets 2 points for each completely correct answer, i.e. maximum 80 points for the whole multiple-choice test. Time limit: 60 min. The MCQ test can be repeated only twice.

To pass the colloquium successfully the student has to obtain at least 40 points.
Language of instruction
English
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2017, autumn 2018, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (autumn 2019, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2019/aVLFA0721p