VSAG021 Modern technologies for genome analysis

Faculty of Medicine
autumn 2020
Extent and Intensity
1/0. 2 credit(s). Type of Completion: z (credit).
Teacher(s)
Mgr. Vojtěch Bystrý, Ph.D. (lecturer)
prof. MUDr. Mgr. Marek Mráz, Ph.D. (lecturer)
MVDr. Boris Tichý, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Šárka Pospíšilová, Ph.D.
Department of Internal Medicine, Hematology and Oncology – Joint workplaces with the University Hospital Brno - workplaces of the Bohunice and Mater. Hospital – Faculty of Medicine
Supplier department: Department of Internal Medicine, Hematology and Oncology – Joint workplaces with the University Hospital Brno - workplaces of the Bohunice and Mater. Hospital – Faculty of Medicine
Course Enrolment Limitations
The course is offered to students of any study field.
The capacity limit for the course is 10 student(s).
Current registration and enrolment status: enrolled: 1/10, only registered: 0/10, only registered with preference (fields directly associated with the programme): 0/10
Course objectives
At the end of the course students should get familiar with the modern molecular-biology techniques and explain the principles of next generation sequencing technologies
Learning outcomes
After taking the course, student will be able to: - apply CRISPR technology in his research - describe the principle of next generation sequencing (NGS) - design NGS experiment - analyze NGS data
Syllabus
  • 1. CRISPR - principles and application 2. Next generation sequencing (NGS) – technological aspects of different NGS platforms 3. Library preparation for NGS 4. Methods for non-coding RNA analysis – miRNA, lncRNA, examples of applications in oncology 5. Data analysis – bioinformatics and statistics 6. Applications and experiment design
Literature
  • Koubková L, Vojtěšek B, Vyzula R. Next generation sequencing -  application in clinical practice. Klin Onkol. 2014;27 Suppl 1:S61-8.
Teaching methods
Lectures.
Assessment methods
written test
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Spring 2011, Spring 2013, Spring 2014, Spring 2015, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (autumn 2020, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2020/VSAG021