aZLPF0521c Patologická fyziologie I - cvičení

Lékařská fakulta
podzim 2023
Rozsah
0/2/0. 30. 2 kr. Ukončení: z.
Vyučující
RNDr. Jan Balvan, Ph.D. (cvičící)
MUDr. Vendula Bartáková, Ph.D. (cvičící)
MUDr. Kamil Ďuriš, Ph.D. (cvičící)
doc. MUDr. Jaromír Gumulec, Ph.D. (cvičící)
MUDr. Michal Jurajda, Ph.D. (cvičící)
MUDr. Jan Máchal, Ph.D. (cvičící)
prof. RNDr. Michal Masařík, Ph.D. (cvičící)
Mgr. Lukáš Pácal, Ph.D. (cvičící)
prof. RNDr. Monika Pávková Goldbergová, Ph.D. (cvičící), prof. MUDr. Julie Dobrovolná, Ph.D. (zástupce)
prof. MUDr. Anna Vašků, CSc. (cvičící)
Bc. Lenka Hladíková (pomocník)
Garance
prof. MUDr. Anna Vašků, CSc.
Ústav patologické fyziologie – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: prof. MUDr. Anna Vašků, CSc.
Dodavatelské pracoviště: Ústav patologické fyziologie – Teoretická pracoviště – Lékařská fakulta
Rozvrh
Po 30. 10. 7:00–12:20 A18/205, Út 31. 10. 7:00–12:20 A18/205, St 1. 11. 7:00–12:20 A18/205, Čt 2. 11. 7:00–12:20 A18/205, Pá 3. 11. 7:00–12:20 A18/205
Předpoklady
aZLFY0422p Fyziologie II - přednáška && ( aZLBC041c Biochemie II - cvičení || aZLBC0422c Biochemie II - cvičení ) && ( aZLBC041s Biochemie II seminář || aZLBC0422s Biochemie II seminář )&& ( aZLAN0222s Anatomie II - sem. || aZLAN0333s Anatomie III - seminář ) && ( aZLAN0222c Anatomie II - pitvy || aZLAN0333c Anatomie III - pitvy ) && aZLHE0322c Histologie a embryol. II -cv. && aZLLT0222s Zákl. lék. terminologie II -s
Physiology, biochemistry
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
The objective of the practical exercises and seminars from pathological physiology is to provide students basic idea about pathological states and experimental work. Students will also acquire practical skills necessary for their subsequent (future) study and work.
Výstupy z učení
Student characterizes state of healthy and disease
Student calls main sources of interindividual variability
Student demonstrates understanding of an influence of external factors on disease development, especially in oral cavity
Student characterizes base features of complex diseases
Student summarises importance of epigenetics
Student describes pathophysiology of stress reaction
Student defines homeostasis term
Student identifies disorder of growth and development from ontogenetic point of view
Student describes results of hypoxia including HIF 1 program
Student explains a difference between local and systemic inflammation
Student explains pathogenesis of oedema
Student discusses etiopathogenesis of the most important ion homeostasis disturbances, especially those of Ca++, Mg++ and K+
Student distinguishes base acid base balance disturbances and possibilities of their compensation
Student applies knowledge of volume and tonicity regulation
Student discusses a role of platelets and physiological endothelium during antiaggregation state and understands base principles of antiaggregation therapy
Student knows principles and performance of base coagulation tests
Student explains wound healing process with examples of pathological healing, especially in oral cavity
Student explains an importance of micronutrients abnormalities, especially considering oral cavity state
Student knows results of abnormal vitamin levels, especially in oral cavity
Student explains mechanism of genomic and non- genomic effects of soluble in lipids vitamins
Student discusses pathophysiology of protein metabolism
Student understands the base principles of regulation of glucose
Student interprets knowledge of immune recognition of own and foreign structure on examples of specifically organ and systemic disorders
Student interprets immunological knowledge of hypersensitive mechanisms in pathophysiology of atopic and allergic changes
Student describes onset, signs and results of heart and vessels remodelling
Student applies chronobiology knowledge for explication of different pathophysiological changes
Osnova
  • Pathophysiology of ventilation disorders and pulmonary gas exchange – spirometry.
  • Cell cycle, oncogenes and supressor genes, cancer development.
  • Essential hypertension (seminar), resting and ambulatory blood pressure (and heart rate) measurements, postural changes, effect of isometric and aerobic exercise.
  • Secondary hypertension (seminar), exp. induced renal ischemia (quantification of renal renin expression).
  • Atherosclerosis (seminar), principles and demonstration of peripheral blood flow examination using ultrasonography.
  • Exp. induced acute renal insufficiency in lab. animal – measurement of GFR based on kinetics of renal inulin excretion.
  • Statistical analysis of experiments (introduction).
  • Exp. induced acute radiation syndrome in lab. animal – haematological consequences.
  • Arrhytmias (seminar), demonstration of selected types of arrhythmias.
  • Acid-base balance, Credits.
Literatura
Výukové metody
practical training
Metody hodnocení
Credit. Practical exercises are compulsory (one absence cen be tellerated, another ones can be excused only in case of sick leave). During the term, tutors can continuously test knowledge in written tests or students can be asked to elaborate special papers.Term tuition (blocks) is completed by credit, conditions for awarding credit are: i) participation in the practical exercises, ii) further individually chosen tutor's criteria.
Vyučovací jazyk
Angličtina
Informace učitele
Students have to follow the safety rules during the practicals. Student can - with tutor's approval - substitute the particular practical with another group in case he/she has a justifiable reason for it.
Další komentáře
Studijní materiály
Předmět je vyučován každoročně.
Studenti opakující 3. ročník nemusejí znovu absolvovat praktika, budou jim uznány zápočty, ke zkoušce mohou přijít v nejbližším zkouškovém období.
Nachází se v prerekvizitách jiných předmětů

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Předmět je zařazen také v obdobích podzim 2017, podzim 2018, podzim 2019, podzim 2020, podzim 2021, podzim 2022, podzim 2024.