ZLGE061p Genetics in Dentistry - lecture

Faculty of Medicine
Spring 2010
Extent and Intensity
0/0.5/0. 1 credit(s). Type of Completion: k (colloquium).
Teacher(s)
prof. MUDr. Anna Vašků, CSc. (lecturer)
prof. MUDr. Lydie Izakovičová Hollá, Ph.D. (lecturer)
Věra Ježková (assistant)
Guaranteed by
prof. MUDr. Lydie Izakovičová Hollá, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Timetable
Mon 22. 2. to Fri 12. 3. Mon 13:00–15:30 206
Prerequisites (in Czech)
( ZLLM0422p Med.Oral.Microbiology II-lect. || ZLLM0522p Medical Microbiology II-lect. ) && ZLIM051p Immunology in Dent. - lecture && ZLBC041p Biochemistry II -lec. && ZLPF0521c Pathophysiol.I - practice
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Genome structure and its reactions on environmental effects.
Mutations in exons, intrones and promoters.
Monogenic and multigenic diseases.
Relations of multigenic diseases and environment.
Molecular biology methods – PCR, RFLP, sequencing.
Functional genomics, proteomics.
Gene therapy and pharmacogenetics.
Genetics of developmental defects of enamel and dentine.
Genetics of craniofacial malformations.
Genetic analysis of oral pathogens.
Genetics of periodontal diseases and tooth caries.
Genes involved in pathogenesis of diseases manifested in oral cavity.
Syllabus
  • Sylabus of lectures:
  • 1. Genome structure and its reactions on environmental effects. Mutations in exons, intrones and promoters. Monogenic and multigenic diseases. Relations of multigenic diseases and environment. Prof. Vašků
  • 2. Molecular biology methods – PCR, RFLP, sequencing. Functional genomics, proteomics. Gene therapy and pharmacogenetics. Prof. Vašků
  • 3. Genetics od developmental defects of enamel and dentin. Genetics of craniofacial malformations. Genetic analysis of oral patogenes. Genetics of periodontal diseases and tooth caries. Genes involved in pathogenesis of diseases manifested in oral cavity. Prof. Izakovičová Hollá
Literature
  • NUSSBAUM, Robert L., Roderick R. MCINNES, Huntington F. WILLARD, James THOMPSON and Margaret Wilson THOMPSON. Klinická genetika : Thompson & Thompson. Translated by Petr Goetz. Vyd. 1. Praha: Triton, 2004, 426, lix. ISBN 8072544756. info
  • Essential genetics :a genomics perspective. Edited by Daniel L. Hartl - Elizabeth W. Jones. 3rd ed. Boston: Jones and Bartlett Publishers, 2002, xxv, 612 s. ISBN 0-7637-1852-1. info
Teaching methods
Lecture.
Assessment methods
Oral exam - colloquium. Student respond to 2 questions - one from general and second from special genetics.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2007, Spring 2008, Spring 2009, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024, spring 2025.
  • Enrolment Statistics (Spring 2010, recent)
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