LF:VSBC041s Biochemistry II -s - Course Information

VSBC041s Biochemistry II -seminar

Faculty of Medicine
Spring 2012

Extent and Intensity

0/2/0. 2 credit(s). Type of Completion: z (credit).

Teacher(s)

Guaranteed by

prof. RNDr. Eva Táborská, CSc.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

VSBC041s/01: Wed 13:35–15:15 A16/213
VSBC041s/02: Wed 13:35–15:15 A16/213
VSBC041s/03: Wed 13:35–15:15 A16/213, J. Tomandl
VSBC041s/04: Wed 13:35–15:15 A16/213, J. Tomandl
VSBC041s/05: Wed 7:30–9:10 A16/213
VSBC041s/06: Wed 7:30–9:10 A16/213
VSBC041s/07: Wed 7:30–9:10 A16/213
VSBC041s/08: Wed 7:30–9:10 A16/213
VSBC041s/09: Wed 10:00–11:40 A16/213
VSBC041s/10: Mon 8:30–10:10 A16/213
VSBC041s/11: Wed 15:30–17:10 A16/213
VSBC041s/12: Wed 15:30–17:10 A16/213
VSBC041s/13: Wed 10:00–11:40 A16/213
VSBC041s/14: Mon 8:30–10:10 A16/213
VSBC041s/15: Mon 15:15–16:55 B09/324
VSBC041s/16: Mon 15:15–16:55 B09/324
VSBC041s/17: Wed 15:30–17:10 A16/213
VSBC041s/18: Wed 15:30–17:10 A16/213
VSBC041s/19: Tue 16:00–17:40 A16/213
VSBC041s/20: Tue 16:00–17:40 A16/213
VSBC041s/30: No timetable has been entered into IS.
VSBC041s/31: No timetable has been entered into IS.
VSBC041s/32: No timetable has been entered into IS.
VSBC041s/33: No timetable has been entered into IS.
VSBC041s/35: No timetable has been entered into IS.

Prerequisites (in Czech)

VSLC011p Med.Chem.- lecture && VSBI0222p Biology II-lect. && ( VSBF011p Biophysics || VLBF011p Biophysics-lect. || STBF011p Biophysics ) && VSBC0221s Biochemistry I sem && VSFY0321c Physiology I - practice && VSFY0321s Physiology I - seminar

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

Stomatology (programme LF, M-ST)
General Medicine (eng.) (programme LF, M-VL)
General Medicine (programme LF, M-VL)

Course objectives

Seminars are complementary to Biochemistry lecture (VSBC041p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome.

Syllabus

methods in clinical chemistry (photometry, nephelometry, turbidimetry, electrophoretic methods). Laboratory tests in clinical biochemistry. Sources of error, assessing the significance of a test result. Enzyme assays in clinical diagnostics. Plasma lipoproteins, interconversion of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion. Blood glucose (sources, comsumption, regulation). Diabetes mellitus. 1st written test (Sources of error of biochemical tests, assessing the significance of results. Digestion, absorption and transport of lipids, lipoproteins, cholesterol, metabolism of lipids at the tissue and organ level, metabolism of steroid hormones, metabolism of glucose in the absorptive, postabsorptive state, and in prolonged fasting (the liver, adipose tissue, and muscle), diabetes and impairments of saccharide metabolism.) *) Catabolism of proteins and of amino acid nitrogen. Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of fixed ammonia, the glutamine cycle. Nitrogenous compounds excreted into the urine. Protein intake and nitrogen balance. Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, postabsorptive state, and prolonged starvation. The liver functions – the role in metabolism of nutrients, hormones, and vitamins. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinaemia. Biotransformation of xenobiotics. 2nd written test (Proteins in nutrition, nitrogen metabolism, integration of intermediary metabolism of nutrients, biochemical functions of the liver, catabolism of haemoglobin, metabolism of xenobiotics.) Neurotransmitter and hormone receptors. Water and mineral metabolism. Electrolyte composition of blood plasma, buffer bases. Respiration – transport of oxygen and CO2. The role of the kidney and the liver in acid-base balance. Blood acid-base parameters, the values indicating particular type of disturbance. 3rd written test (Neurotransmitter and hormone receptors, water and mineral metabolism, iontograms, acid-base balance.) Major functions of the kidney. Glomerular filtration. Tubular resorption and secretion. Urine - normal constituents, amounts of nitrogenous compounds excreted per 24 h. The proteinuria types. Urinary sediment, renal stones. Biochemistry of muscle tissue. Energy resources in working muscle. Nitroxide and smooth muscles, mechanism of action. Written test for the students who did not reach the required result in preceding tests. Consultation. Credits.

Literature

TOMANDL, Josef, Eva TÁBORSKÁ, Markéta BOČKOVÁ, Hana BOCHOŘÁKOVÁ, Jiří DOSTÁL, Petr KAPLAN, Vladimír PALYZA, Hana PAULOVÁ, Jaromír SLÁMA, Jaroslava TALLOVÁ and Ingrid WILHELMOVÁ. Semináře z biochemie II (Seminary of biochemistry II.). 2. přeprac. vydání. Brno: Masarykova univerzita, 1998, 147 pp. ISBN 80-210-1895-X. info
Biochemistry :seminars. Edited by Josef Tomandl - Eva Táborská. 1. vyd. Brno: Masarykova univerzita, 1996, 146 s. ISBN 80-210-1417-2. info

Teaching methods

Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.

Assessment methods

course-unit credit. Conditions for giving the course-unit credit. Full attendance in all lessons. Three short tests are written during the semester. Students that will obtain 70% points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 12 points. Students that will not fulfill this limit will be allowed to repeat the test once. Remedial dates for writing the credit test will be scheduled till 15.6.2008. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry I.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught each semester.
Information on course enrolment limitations: mimo studenty LF, max 5 posluchačů z MU, po dohodě s vedoucím ústavu

Listed among pre-requisites of other courses

VLLM0522c Medical Microbiology II - practice
VLLM0421c && (VLBC0422c || VSBC041c) && (VLBC0422s || VSBC041s)

Teacher's information

http://www.med.muni.cz/toCP1250.cs/biochem/vyuka.html

The course is also listed under the following terms Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2013, Spring 2014, Spring 2015, Spring 2016.

Enrolment Statistics (Spring 2012, recent)
Permalink: https://is.muni.cz/course/med/spring2012/VSBC041s

LF:VSBC041s Biochemistry II -s - Course Information

VSBC041s Biochemistry II -seminar

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