VSBC041s Biochemistry II - seminar

Faculty of Medicine
Spring 2014
Extent and Intensity
0/2/0. 2 credit(s). Type of Completion: z (credit).
Teacher(s)
doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
prof. MUDr. Vladimír Palyza, CSc. (seminar tutor)
RNDr. Hana Paulová, CSc. (seminar tutor)
Mgr. Jiří Slanina, Ph.D. (seminar tutor)
prof. RNDr. Eva Táborská, CSc. (seminar tutor)
doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
PharmDr. Lenka Adámková, Ph.D. (assistant)
RNDr. Hana Bochořáková (assistant)
Ing. Martina Čarnecká, Ph.D. (assistant)
Mgr. Jana Gregorová, Ph.D. (assistant)
MUDr. Miroslava Hlaváčová, Ph.D. (assistant)
MUDr. Michaela Králíková, Ph.D. (assistant)
Mgr. Milena Matejovičová, Ph.D. (assistant)
Ing. Jitka Melounová, Ph.D. (assistant)
Lenka Nerudová (assistant)
doc. Mgr. Ondřej Peš, Ph.D. (assistant)
Ing. Jana Simonová, Ph.D. (assistant)
PharmDr. Kristýna Šebrlová, Ph.D. (assistant)
Mgr. Marie Tomandlová, Ph.D. (assistant)
Guaranteed by
prof. RNDr. Eva Táborská, CSc.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Timetable of Seminar Groups
VSBC041s/01: Wed 13:35–15:15 A16/213, J. Tomandl
VSBC041s/02: Wed 13:35–15:15 A16/213, J. Tomandl
VSBC041s/03: Wed 13:35–15:15 A16/213, H. Paulová
VSBC041s/04: Wed 13:35–15:15 A16/213, H. Paulová
VSBC041s/05: Wed 7:30–9:10 A16/213, J. Slanina
VSBC041s/06: Wed 7:30–9:10 A16/213, J. Slanina
VSBC041s/07: Wed 7:30–9:10 A16/213, H. Paulová
VSBC041s/08: Wed 7:30–9:10 A16/213, H. Paulová
VSBC041s/09: Wed 10:00–11:40 A16/213, H. Paulová
VSBC041s/10: Mon 8:30–10:10 A16/213, J. Dostál
VSBC041s/11: Wed 15:30–17:10 A16/213, J. Dostál
VSBC041s/12: Wed 15:30–17:10 A16/213, J. Dostál
VSBC041s/13: Wed 10:00–11:40 A16/213, H. Paulová
VSBC041s/14: Mon 15:15–16:55 B09/324, J. Slanina
VSBC041s/15: Mon 15:15–16:55 B09/324, J. Slanina
VSBC041s/16: Mon 8:30–10:10 A16/213, J. Dostál
VSBC041s/17: Wed 15:30–17:10 A16/213
VSBC041s/18: Wed 15:30–17:10 A16/213
VSBC041s/30: No timetable has been entered into IS. J. Dostál
VSBC041s/31: No timetable has been entered into IS. J. Dostál
VSBC041s/32: No timetable has been entered into IS. J. Dostál
VSBC041s/33: No timetable has been entered into IS. J. Dostál
VSBC041s/34: No timetable has been entered into IS. J. Dostál
VSBC041s/35: No timetable has been entered into IS. J. Dostál
VSBC041s/36: No timetable has been entered into IS. J. Dostál
VSBC041s/37: No timetable has been entered into IS. J. Dostál
Prerequisites (in Czech)
VSLC011p Med. Chemistry - lecture && VSBI0222p Biology II -lect. && ( VSBF011p Biophysics || VLBF011p Biophysics -lect. || STBF011p Biophysics ) && VSBC0221s Biochemistry I sem && VSFY0321c Physiology I - practice && VSFY0321s Physiology I - seminar
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Seminars are complementary to Biochemistry lecture (VSBC041p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome.
Syllabus
  • methods in clinical chemistry (photometry, nephelometry, turbidimetry, electrophoretic methods). Laboratory tests in clinical biochemistry. Sources of error, assessing the significance of a test result. Enzyme assays in clinical diagnostics. Plasma lipoproteins, interconversion of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion. Blood glucose (sources, comsumption, regulation). Diabetes mellitus. 1st written test (Sources of error of biochemical tests, assessing the significance of results. Digestion, absorption and transport of lipids, lipoproteins, cholesterol, metabolism of lipids at the tissue and organ level, metabolism of steroid hormones, metabolism of glucose in the absorptive, postabsorptive state, and in prolonged fasting (the liver, adipose tissue, and muscle), diabetes and impairments of saccharide metabolism.) *) Catabolism of proteins and of amino acid nitrogen. Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of fixed ammonia, the glutamine cycle. Nitrogenous compounds excreted into the urine. Protein intake and nitrogen balance. Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, postabsorptive state, and prolonged starvation. The liver functions – the role in metabolism of nutrients, hormones, and vitamins. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinaemia. Biotransformation of xenobiotics. 2nd written test (Proteins in nutrition, nitrogen metabolism, integration of intermediary metabolism of nutrients, biochemical functions of the liver, catabolism of haemoglobin, metabolism of xenobiotics.) Neurotransmitter and hormone receptors. Water and mineral metabolism. Electrolyte composition of blood plasma, buffer bases. Respiration – transport of oxygen and CO2. The role of the kidney and the liver in acid-base balance. Blood acid-base parameters, the values indicating particular type of disturbance. 3rd written test (Neurotransmitter and hormone receptors, water and mineral metabolism, iontograms, acid-base balance.) Major functions of the kidney. Glomerular filtration. Tubular resorption and secretion. Urine - normal constituents, amounts of nitrogenous compounds excreted per 24 h. The proteinuria types. Urinary sediment, renal stones. Biochemistry of muscle tissue. Energy resources in working muscle. Nitroxide and smooth muscles, mechanism of action. Written test for the students who did not reach the required result in preceding tests. Consultation. Credits.
Literature
    required literature
  • Podklady pro semináře jsou ve studijních materiálech předmětu VSBC041s. The seminar files are available in IS, Study materials VSBC041s.
Teaching methods
Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
Assessment methods
course-unit credit. Conditions for giving the course-unit credit. Full attendance in all lessons. Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 14 points. All absences must be made before writing the credit test. Students are allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry I.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught each semester.
Information on course enrolment limitations: mimo studenty LF, max 5 posluchačů z MU, po dohodě s vedoucím ústavu
Listed among pre-requisites of other courses
Teacher's information
http://www.med.muni.cz/toCP1250.cs/biochem/vyuka.html
The course is also listed under the following terms Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2015, Spring 2016.
  • Enrolment Statistics (Spring 2014, recent)
  • Permalink: https://is.muni.cz/course/med/spring2014/VSBC041s