LF:BVBC0221s Biochemistry I sem - Course Information

BVBC0221s Biochemistry I - seminar

Extent and Intensity

0/2. 1 credit(s). Type of Completion: z (credit).

Teacher(s)

PharmDr. Lenka Adámková, Ph.D. (seminar tutor)
RNDr. Hana Bochořáková (seminar tutor)
Ing. Martina Čarnecká, Ph.D. (seminar tutor)
doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
Mgr. Jana Gregorová, Ph.D. (seminar tutor)
MUDr. Michaela Králíková, Ph.D. (seminar tutor)
Mgr. Milena Matejovičová, Ph.D. (seminar tutor)
Ing. Jitka Melounová, Ph.D. (seminar tutor)
prof. MUDr. Vladimír Palyza, CSc. (seminar tutor)
RNDr. Hana Paulová, CSc. (seminar tutor)
doc. Mgr. Ondřej Peš, Ph.D. (seminar tutor)
Ing. Jana Simonová, Ph.D. (seminar tutor)
Mgr. Jiří Slanina, Ph.D. (seminar tutor)
PharmDr. Kristýna Šebrlová, Ph.D. (seminar tutor)
prof. RNDr. Eva Táborská, CSc. (seminar tutor)
doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
Lenka Nerudová (assistant)

Guaranteed by

prof. RNDr. Eva Táborská, CSc.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine

Timetable

Fri 7:30–9:10 B11/234

Prerequisites (in Czech)

BVLC011c Medical Chemistry -p && BVLC011s Med.Chem.-seminar && ZC011 Handling chemical substances

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ) (2)

Course objectives

Seminars are complementary to Biochemistry lecture. At the end of the course student understand and can describe the major metabolic pathways and their significance.

Syllabus

• Introduction into the metabolism of cells (differences between prokatyotic and eukaryotic cell, compartmentation of metabolic processes, enzyme markers of cell fractions, non-covalent interactions in the cell and their significance). Structure of hemoglobin and its relationship to the function. Hb types in the blood of healthy subjects, HbCO and MetHb, abnormal Hb types. Enzymes - reaction rate, progress curve, the Michaelis plot and Km, enzyme inhibition. Coenzymes, their relationship to vitamins. Written test I (Biochemical methods, hemoglobin, enzymology, coenzymes.) Membrane structure and assembly. Transport across membranes. Metabolism of glucose: Glycolysis under anaerobic and aerobic conditions and the oxidation of pyruvate. Gluconeogenesis. Glycogenesis and glycogenolysis. Metabolism of proteins. Common features of amino acid conversion. The synthesis of urea. Nitrogen balance. Important reactions in amino acid catabolism. Written test II (Membranes, transport across membranes, metabolism of saccharides and amino acids.) Biosynthesis and desaturation of fatty acids. The sources of essential fatty acids. Metabolism of triacylglycerols. Metabolism of phospholipids. Biosynthesis of eicosanoids. Peroxidation of lipids. Written test III (Metabolism of lipids.) The citric acid cycle. The respiratory chain and oxidative phosphorylation. Replication. Transcription. Translation.

Literature

required literature
• TOMANDL, Josef, Eva TÁBORSKÁ, Jiří DOSTÁL, Hana BOCHOŘÁKOVÁ, Jaromír SLÁMA and Vladimír PALYZA. Biochemie I - Semináře (Biochemistry I - Seminars). 3. přepracované. Brno: Masarykova univerzita, 2012, 83 pp. ISBN 978-80-210-5740-1. info
• TOMANDL, Josef, Eva TÁBORSKÁ, Jiří DOSTÁL, Hana BOCHOŘÁKOVÁ, Jaromír SLÁMA and Vladimír PALYZA. Biochemistry I- Seminars. 2nd revised ed. Brno: Masarykova univerzita, 2012, 83 pp. ISBN 978-80-210-5741-8. info

Teaching methods

Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.

Assessment methods

Conditions for giving the course-unit credit Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester, limit 14 points. Students that will not fulfill this limit will be allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry I.

Language of instruction

Czech

Further Comments

The course is taught annually.

• Enrolment Statistics (Spring 2013, recent)
  
• Permalink: https://is.muni.cz/course/med/spring2013/BVBC0221s