LF:BVBC0221s Biochemistry sem - Course Information

BVBC0221s Biochemistry - seminar

Extent and Intensity

0/2/0. 1 credit(s). Type of Completion: z (credit).

Teacher(s)

Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
MUDr. Michaela Králíková, Ph.D. (seminar tutor)
RNDr. Hana Paulová, CSc. (seminar tutor)
Mgr. Jiří Slanina, Ph.D. (seminar tutor)
prof. RNDr. Eva Táborská, CSc. (seminar tutor)
doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)

Guaranteed by

Mgr. Marie Tomandlová, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine

Timetable

Fri 5. 3. 8:00–9:40 A16/213, Fri 12. 3. 8:00–9:40 A16/213, Fri 19. 3. 8:00–9:40 A16/213, Fri 26. 3. 8:00–9:40 A16/213, Fri 9. 4. 8:00–9:40 A16/213, Fri 16. 4. 8:00–9:40 A16/213, Fri 23. 4. 8:00–9:40 A16/213, Fri 30. 4. 8:00–9:40 A16/213, Fri 7. 5. 8:00–9:40 A16/213, Fri 14. 5. 8:00–9:40 A16/213, Fri 21. 5. 8:00–9:40 A16/213, Fri 28. 5. 8:00–9:40 A16/213, Fri 4. 6. 8:00–9:40 A16/213, Fri 11. 6. 8:00–9:40 A16/213

Prerequisites (in Czech)

BVLC011c Medical Chemistry -p && BVLC011s Med.Chem.-seminar

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ) (2)
• Dietitian (programme LF, B-NUT)

Course objectives

The student will get acquainted with the basic metabolic pathways and their signifikance.

Learning outcomes

In the end of the course will students:
- understand the properties and function of enzymes
- describes basic catabolic and anabolic pathways of carbohydrate, lipid and protein metabolism
- understand the principles of energy production, utilization and deposition at the cellular level
- explain the function of cell membranes and the transport processes on the membrane
- describe protein synthesis, understand the relationship between protein structure and function
- explain the function of hemoglobin in oxygen transport and maintaining acid-base balance

Syllabus

• Introduction into the metabolism of cells. Membrane structure and assembly. Transport across membranes.
• Enzymes - reaction rate, progress curve, the Michaelis plot and Km, enzyme inhibition.
• Coenzymes, their relationship to vitamins.
• The citric acid cycle.
• The respiratory chain and oxidative phosphorylation.
• Metabolism of glucose: Glycolysis under anaerobic and aerobic conditions and the oxidation of pyruvate.
• Gluconeogenesis. Glycogenesis and glycogenolysis.
• Metabolism of proteins. Common features of amino acid conversion. The synthesis of urea. Nitrogen balance.
• Important reactions in amino acid catabolism.
• Biosynthesis and desaturation of fatty acids. The sources of essential fatty acids. Metabolism of triacylglycerols.
• Metabolism of lipids. Biosynthesis of eicosanoids. Peroxidation of lipids.
• Metabolism of heam. Hemoglobin.
• Biosynthesis and catabolism of purine and pyrimidine nucleotides.

Literature

required literature
• Podklady k seminářům dostupné v Informačním systému

Teaching methods

Course is based on group discusion to the given topics. Complementary materials are available in section Study materials.

Assessment methods

Course-unit credit.
Conditions for giving the course-unit credit: full attendance in all lessons (or making up all missing and justified lessons) and successful accomplished of credit test.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
General note: Úspěšné absolvování je předpokladem pro přistoupení ke zkoušce v předmětu BVBC0221p.
Information on the extent and intensity of the course: 30.

• Enrolment Statistics (spring 2021, recent)
  
• Permalink: https://is.muni.cz/course/med/spring2021/BVBC0221s