LF:BVBC0221p Biochemistry - lect. - Course Information
BVBC0221p Biochemistry - lecture
Faculty of Medicinespring 2022
- Extent and Intensity
- 2/0/0. 3 credit(s). Type of Completion: zk (examination).
- Teacher(s)
- Mgr. Marie Tomandlová, Ph.D. (lecturer)
doc. RNDr. Jiří Dostál, CSc. (lecturer)
doc. RNDr. Josef Tomandl, Ph.D. (lecturer)
MUDr. Michaela Králíková, Ph.D. (assistant)
Bc. Ivana Ševčíková (assistant)
RNDr. Hana Paulová, CSc. (alternate examiner)
Mgr. Jiří Slanina, Ph.D. (alternate examiner)
prof. RNDr. Eva Táborská, CSc. (alternate examiner) - Guaranteed by
- Mgr. Marie Tomandlová, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine - Timetable
- Wed 16. 2. 8:00–9:50 B11/234, Wed 23. 2. 8:00–9:50 B11/234, Wed 2. 3. 8:00–9:50 B11/234, Wed 9. 3. 8:00–9:50 B11/234, Wed 16. 3. 8:00–9:50 B11/234, Wed 23. 3. 8:00–9:50 B11/234, Wed 30. 3. 8:00–9:50 B11/234, Wed 6. 4. 8:00–9:50 B11/234, Wed 13. 4. 8:00–9:50 B11/234, Wed 20. 4. 8:00–9:50 B11/234, Wed 27. 4. 8:00–9:50 B11/234, Wed 4. 5. 8:00–9:50 B11/234, Wed 11. 5. 8:00–9:50 B11/234, Wed 18. 5. 8:00–9:50 B11/234, Wed 25. 5. 8:00–9:50 B11/234
- Prerequisites (in Czech)
- BVLC011s Med.Chem.-seminar && BVLC011c Medical Chemistry -p
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- Nutritive therapist (programme LF, B-SZ) (2)
- Dietitian (programme LF, B-NUT)
- Course objectives
- The aim of the course is to obtain knowledge on essential metabolic processes on the cell level. The course provides the essential knowledge for future understanding of metabolism on organe and inter-organe level and its disturbances.
- Learning outcomes
- In the end of the course will students:
- understand the properties and function of enzymes
- describes basic catabolic and anabolic pathways of carbohydrate, lipid and protein metabolism, and their relationships
- understand the principles of energy production, utilization and deposition at the cellular level
- explain the function of cell membranes and the transport processes on the membrane
- describe protein synthesis, understand the relationship between protein structure and function
- explain the function of hemoglobin in oxygen transport and maintaining acid-base balance - Syllabus
- Enzymes. Characteristic features of biocatalysis, enzyme structure and function, nomenclature and classification of enzymes. Kinetics of enzyme catalyzed reactions. Assays of enzyme activity. Factors affecting catalytic aktivity of enzymes, types of enzyme inhibition.
- Enzyme cofactors, review of structures and functions. Metabolism - basic concepts and design. Biological oxidations, generation of high-energy compounds.
- Interrelationships among the major pathways involved in energy metabolism. The citric acid cycle. Oxidative phosphorylation.
- Saccharide metabolism: the glycolytic pathway.
- Gluconeogenesis. Glycogen biosynthesis and breakdown.
- The pentose phosphate pathway.Interconversions of monosaccharides and of their derivatives.
- Protein and amino acid metabolism. The common reactions in amino acid degradation. The ureosynthetic cycle.
- Metabolic breakdown of individual amino acids.
- Biosynthesis and breakdown of fatty acids, ketogenesis. Synthesis of triacylglycerols.
- Metabolism of phospholipids and glycolipids. Synthesis of eicosanoids. Biosynthesis and transformations of cholesterol, biosynthesis of bile acids.
- Metabolism of haem. Haemoglobin, myoglobin. Hemoglobinopathy.
- Biosynthesis and catabolism of purine and pyrimidine nucleotides. DNA replication.
- DNA transcription. Regulation of gene expression.
- Protein synthesis and post-translational processing.
- Literature
- required literature
- LEDVINA, Miroslav, Alena STOKLASOVÁ and Jaroslav CERMAN. Biochemie pro studující medicíny. 3. vydání. Praha: Univerzita Karlova, nakladatelství Karolinum, 2020, 269 stran. ISBN 9788024647487. info
- recommended literature
- MATOUŠ, Bohuslav. Základy lékařské chemie a biochemie. 1. vyd. Praha: Galén, 2010, xv, 540. ISBN 9788072627028. info
- KOOLMAN, Jan and Klaus-Heinrich RÖHM. Barevný atlas biochemie. Grada. Praha, 2012, 498 pp. ISBN 978-80-247-2977-0. info
- FERRIER, Denise R. Biochemistry. Seventh edition. Philadelphia: Wolters Kluwer, 2017, viii, 567. ISBN 9781496363541. info
- Teaching methods
- Teaching form is lecture.
- Assessment methods
- Oral examination.
Students draw a total of three questions. - Language of instruction
- Czech
- Follow-Up Courses
- Further comments (probably available only in Czech)
- Information on completion of the course: přistoupení ke zkoušce je podmíněno úspěšným ukončením předmětů BVLC011p a BVBC0221s.
The course is taught annually.
Information on the extent and intensity of the course: 30. - Listed among pre-requisites of other courses
- BVBV0321s Nutritional Biochemistry - seminary
BVLC011p && BVBC0221p - BVLV0321c Nutrition therapy I - exercises
BKFY0222p&&BVBC0221p&&BVDP0221 - BVLV0321p Nutrition therapy I - lecture
BKFY0222p&&BVBC0221p&&BVDP0221 - BVPF0321p Pathophysiology I - lecture
BKFY0222p && BVBC0221p - BVPX0321 Practical training I
BVKP0222&&BVZO021p&&BKFY0222p&&BVBC0221p - BVTO0311c Medical toxicology - laboratory course
BVBC0221p||VSBC0221p&&BVEK011p - BVTO0311p Medical toxicology - lecture
BVBC0221p||VSBC0221p&&BVEK011p - BVVL0421p Internal Medicine I
BVPF0321p&&BVZI0321&&BVBC0221p - BVVP0321c Nutrition in health promotion and public health I - exercises
BVCP0222p&&BVCP0222c&&BKFY0222p&&BVBC0221p&&BKUV011p
- BVBV0321s Nutritional Biochemistry - seminary
- Enrolment Statistics (spring 2022, recent)
- Permalink: https://is.muni.cz/course/med/spring2022/BVBC0221p