VLBI0222p Medical Biology II - lecture

Faculty of Medicine
spring 2023
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
Mgr. Kateřina Francová, Ph.D. (lecturer)
Mgr. Kateřina Straková, Ph.D. (lecturer)
doc. Mgr. Jiří Šána, Ph.D. (lecturer)
Jana Růžičková (assistant)
Guaranteed by
prof. RNDr. Ondřej Slabý, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Ing. Lívia Eiselleová, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Mon 13. 2. to Wed 10. 5. Wed 8:00–9:40 B22/116 aula
Prerequisites
VLBI0121c Biology I -pract. && VLBI0121p Biology I - lect.
Knowledge of high-school biology, previous lectures, and practical classes on the subject are prerequisites for studying the course. Expected knowledge for each lecture is specified in the course syllabus. The literature recommended to study for each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding of the basic principles of human genetics
- understanding of the mechanisms of cancer development
- acquaintance with the basics of genomics, immunogenetics, epigenetics, gene therapy, tissue engineering and evolutionary biology
Learning outcomes
After completing the course, the student will be able to:
- explain and apply basic principles of human genetics
- explain the role of medical biology in the development of modern therapies (e.g. molecular therapies for cancer)
- explain the basic principles of current methods used in gene therapy and cell therapies
- understand the significance of the human microbiome in human health and disease
- be knowledgeable in basic modern approaches to studying various diseases and to personalised medicine (genomics)
Syllabus
  • Introduction to Genetics I – Genetics in Medicine, Mendelian Inheritance, Autosomal and Gonosomal Inheritance, Chromosome Abnormalities
  • Introduction to Genetics II – Multifactorial Inheritance, Genetic Linkage, Population Genetics
  • Human Genome
  • Epigenetics – Interaction of Genes and Environment
  • Immunogenetics
  • Cancer Biology I – Carcinogenesis, Hallmarks of Cancer
  • Cancer Biology II – Application of Cancer Biology into Cancer Diagnostics and Therapy
  • Bacterial and Viral Genomics
  • Gene Therapy
  • Human Microbiome
  • Stem Cells and Tissue Engineering
  • Introduction to Human Ontogeny (Pre- and Postnatal Development)
  • Evolutionary Biology
Literature
    required literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • D. Peter Snustad Michael J. Simmons. Genetika. Brno, 2017. ISBN 9788021086135. info
Teaching methods
lecture every week
Assessment methods
The course of Medical Biology II builds on the knowledge gained from Medical Biology I and is completed with an oral exam based on topics discussed at lectures and practices of both semesters.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses

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Teacher's information
https://is.muni.cz/auth/el/med/jaro2023/VLBI0222p/index-ebtzDw.qwarp
Lectures take place every week. We recommend following the Interactive syllabus of the course, where students can find all relevant information (schedule, substitutions, public holidays etc.), and also corresponding study literature for each week, and links to animations and videos relevant to the topic https://is.muni.cz/auth/el/med/jaro2023/VLBI0222p/index-ebtzDw.qwarp
The course is also listed under the following terms Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2024, spring 2025.
  • Enrolment Statistics (spring 2023, recent)
  • Permalink: https://is.muni.cz/course/med/spring2023/VLBI0222p