Bi2MP_BZZL Cellular bases of life actions

Faculty of Education
Spring 2013
Extent and Intensity
0/0/2. 3 credit(s). Type of Completion: k (colloquium).
Teacher(s)
Mgr. Martina Jančová, Ph.D. (seminar tutor)
Guaranteed by
Mgr. Martina Jančová, Ph.D.
Department of Biology – Faculty of Education
Contact Person: Mgr. Martina Jančová, Ph.D.
Supplier department: Department of Biology – Faculty of Education
Timetable of Seminar Groups
Bi2MP_BZZL/OS01: Wed 9:20–11:00 učebna 2, M. Jančová
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
At the end of this course, students should be able to:
- distinguish noncellular and cellular (pro- and eukaryotic) organisms.
- describe memory, membrane and cytoskeletal principles of the cells.
- understand and explain basic processes which take place at the cellular level in living organisms - the grounds of cellular and molecular biology and genetics.
- illustratively explain the center of a genetic code, its redundancy and universality by way of selected examples.
- describe in detail the expression of genetic information, particularly transcription and translation.
- explain nucleosome structure of chromosome.
- describe the course of cell cycle and analyse the importance of its parts; student can relate the significance of understanding the cell cycle conception for applied science and for man’s healthy life – cancer treatment, stem cells, organs transplantation, pharmacogenetics.
- explain the terms: telomere, apoptosis, necrosis and elucidate an importance of these structures and processes for cellular (organism’s) senescence and death.
- describe the organization of membrane and cytoskeletal structures and understand their functions in eukaryotic cell.
- illustratively explain the process of signals reception and their processing by cell as well matter transport inside and out of an eukaryotic cell.
- understand cell position in multicellular (human) organism.
Syllabus
  • Taxonomy of organisms (noncellular and cellular organisms - differencies and basic division).
  • Cell theory and principles of cells functional organization (memory, membrane and cytoskeletal principles).
  • Differencies between pro- and eukaryotic cells.
  • Cell cycle. Cell necrosis, cell apoptosis. Destiny of cells in multicellular (human) organism.
  • Memory principle. Central dogma of molecular biology (replication, transcription, reverse transcription, translation).
  • Expression of genetic information, genetic code, posttranscriptional and posttranslational modifications.
  • News from molecular genetics: human genes for sports performance, for issue of pathological addictions leading to obesity, etc.
  • Membrane principle. General structure of biomembranes. Membrane transfer (diffusion, osmosis, membrane channels, carrier proteins, endo- and exocytosis). Membrane receptors. Signaling cascades. Types of interactions between a cell and a virus.
  • Plasmatic membrane. Individual organelles of eukaryotic cells - their structure and function in cells.
  • Cytoskeletal principle. Microtubules, actin microfilaments and intermediate filaments - their structure and function in cells.
  • Molecular motors. Movement at the cellular level. Nuclear skeleton, membrane skeleton, exoskeleton.
  • Cell in light and electron microscope. Fluorescent microscopy – principle, application. Direct and indirect fluorescence. Visualization of cell structures by use of fluorescent microscopy.
Literature
    recommended literature
  • Buněčné základy životních dějů. Edited by Václav Kubišta. 1. vyd. Praha: Scientia, 1998, 210 s., il. ISBN 80-7183-109-3. info
    not specified
  • ALBERTS, Bruce. Základy buněčné biologie :úvod do molekulární biologie buňky. 1. vyd. Ústí nad Labem: Espero, 1999, xxvi, 630. ISBN 80-902906-0-4. info
  • NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
  • ZÁVODSKÁ, Radka. Biologie buněk : základy cytologie, bakteriologie, virologie. 1. vyd. Praha: Scientia, 2006, 160 s. ISBN 8086960153. info
  • KUBIŠTA, Václav. Obecná biologie : úvodní učební text biologie pro 1. ročník gymnázií. 3. upr. vyd. Praha: Fortuna, 2000, 103 s. ISBN 8071687146. info
  • BERGER, Josef. Biologie buněk. 1. vyd. České Budějovice: KOPP, 2000, 211 s. ISBN 80-7232-119-6. info
  • HEJTMÁNEK, Milan. Cvičení z biologie. 2. vyd. Brno: Univerzita J.E. Purkyně, 1988, 200, xiii. ISBN 80-210-0179-8. info
  • ROSYPAL, Stanislav, Jiří DOŠKAŘ, Roman PANTŮČEK, Jana KAILEROVÁ, Jiřina RELICHOVÁ, Vladislava RŮŽIČKOVÁ, Jan ŠMARDA, Jan ŠMARDA and Jiří ŠTĚPÁN. TERMINOLOGIE MOLEKULÁRNÍ BIOLOGIE. České odborné termíny, definice a anglické ekvivalenty (Terminology of molecular biology). První vydání. Brno: Vydavatel Prof. RNDr. Stanislav Rosypal, DrSc. Vodova 80, 612 00 Brno, 2001, 300 pp. ISBN 80-902562-3-6. URL info
Teaching methods
Powerpoint presentations, educational videos and animations, making of cell's model.
Assessment methods
Colloquium,oral.
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is also listed under the following terms Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, Spring 2019.
  • Enrolment Statistics (Spring 2013, recent)
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