F1SU1_13 Physical and Colloid Chemistry

Faculty of Pharmacy
Spring 2020
Extent and Intensity
2/2/0. 6 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. Mgr. Jan Muselík, Ph.D. (lecturer)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (lecturer)
doc. Mgr. Jan Muselík, Ph.D. (seminar tutor)
Mgr. Sylvie Pavloková, Ph.D. (seminar tutor)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (seminar tutor)
PharmDr. Jiří Zeman, Ph.D. (seminar tutor)
Guaranteed by
prof. PharmDr. Mgr. David Vetchý, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the discipline is to make students familiar with basic knowledge of the physical chemistry, which constitutes part of the theoretical basis, necessary for understanding of processes delivered within disciplines in further stages of the study. Lectures are divided according to basic part of physical and colloid chemistry such as thermodynamics, kinetics of chemical reactions, behaviour of solutions, electrochemistry, phase balances, behaviour of phase interfaces, behaviour of colloid systems. In laboratories students learn the experimental technique of physical chemistry while in seminars students will get acquaintance with physical chemistry calculations, which are integral parts of knowledge required in the discipline.
Syllabus
  • LECTURES:
  • Thermodynamics.
  • Solubility: solubility gas/liquid, liquid/liquid, solid/liquid. Solubility of salts, poor soluble electrolytes, weak electrolytes and their salts.
  • Electrochemistry.
  • Phase equilibrium.
  • Phase interfaces.
  • Diffusion, dissolution and their importance in drug development.
  • Kinetics: rates and orders of reactions. Influence of temperature and other factors on reaction rates. The importance of kinetics in formulation and development of pharmaceuticals.
  • Rheology: Newtonian systems, non-Newtonian systems, thixotropy, determination of rheologic properties, viscoelasticity, application in pharmacy.
  • Colloids.

    PRACTICAL TRAINING:
  • States of matter and thermodynamics - calculations
  • Phase equilibria, chemical kinetics and electrochemistry - calculations
  • Density determination by pycnometric method
  • Partitioning of succinic acid in the system butanol-water
  • Determination of upper critical dissolution temperature of the mixture phenol-water
Literature
    recommended literature
  • Atkins, P.W. Physical Chemistry. Oxford Univ.Press, Oxford, 1997. info
  • Kišová, L. , Trnková, L. Příklady z fyzikální chemie. PřF MU Brno, 1993. info
  • Fischer, O. a kol. Fyzikální chemie. SPN Praha, 1983. info
  • Vodrážka, Z. Fyzikální chemie pro biologické vědy. Academia, Praha, 1983. info
  • Moore, W.J. Fyzikální chemie. SNTL, Praha, 1979. info
  • Brdička, R., Dvořák, J. Základy fyzikální chemie. Academia, 1977. info
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
Participate in exercises and seminars in the full range given by the syllabus, properly write protocols from laboratory exercises. Demonstrate ongoing knowledge during seminars and exercises. Part of the credit is a written test for calculations and a test of knowledge of the content of practical training.
The course is also listed under the following terms Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.
  • Enrolment Statistics (Spring 2020, recent)
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