FAFO2_13 Dosage Forms and Biopharmacy II

Faculty of Pharmacy
Spring 2022
Extent and Intensity
3/6/0. 11 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. PharmDr. Aleš Franc, Ph.D. (lecturer)
doc. PharmDr. Jan Gajdziok, Ph.D. (lecturer)
doc. PharmDr. Kateřina Kubová, Ph.D. (lecturer)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (lecturer)
PharmDr. Jakub Vysloužil, Ph.D. (lecturer)
doc. PharmDr. Aleš Franc, Ph.D. (seminar tutor)
doc. PharmDr. Jan Gajdziok, Ph.D. (seminar tutor)
doc. PharmDr. Kateřina Kubová, Ph.D. (seminar tutor)
PharmDr. Jakub Vysloužil, Ph.D. (seminar tutor)
PharmDr. Miroslava Pavelková, Ph.D. (seminar tutor)
Guaranteed by
doc. PharmDr. Kateřina Kubová, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Timetable
Thu 9:15–11:45 18-122
  • Timetable of Seminar Groups:
FAFO2_13/01: Thu 12:30–14:00 18-122, Thu 14:00–17:30 18-138
FAFO2_13/02: Thu 12:30–17:30 18-107
Prerequisites
Dosage Forms and Biopharmacy I
Students can study this course only after completing the course Dosage Forms and Biopharmacy I
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 20 student(s).
Current registration and enrolment status: enrolled: 0/20, only registered: 0/20
fields of study / plans the course is directly associated with
Course objectives
One of the main obligatory pharmaceutical disciplines dealing with preparation, manufacturing and quality control of medicaments including technological procedures, equiment, excipients and appropriate analytical devices. It covers the influence of the application form on drug bioavailability.
Learning outcomes
After completing the course, student will: - theoretically know the classification, requirements, excipients, technological process of preparation and production of solid dosage forms, including their evaluation; - theoretically know the classification, requirements, excipients, technological process of preparation and production of dosage forms with controlled drug release, including their evaluation; - know the basic aspects of dosage forms in relation to the drug bioavailability - practically know the preparation of semisolid and solid dosage forms in pharmacy conditions;
Syllabus
  • Topic of lecture

    Semisolid dosage forms – ointments
    Semisolid dosage forms - creams, gels, pastes
    Dosage forms for rectal application
    Dosage forms for vaginal application.
    Pharmaceutical incompatibilities in dosage forms.
    Granules, granulation methods. Evaluation of powders and granules.
    Tablets, their production, and evaluation.
    Coated products, their production and evaluation.
    Oral dosage forms with controlled drug release
    Pharmaceutical aerodispersions.
    Validation in pharmaceutical technology
    Regulatory authorities evaluation of dosage forms
    Development of new drugs from galenical perspective

    Practical labs

    Semisolid dosage forms - ointments
    Semisolid dosage forms - creams
    Semisolid dosage forms - pastes, gels
    Rectal and vaginal dosage forms - theoretical aspect of preparation, calibration coefficient
    Preparation of rectal suppositories
    Preparation of vaginal globules
    Incompatibilities in liquid, semisolid and solid dosage forms - theoretical aspect of preparation
    Technological processes in preparation of difficult prescriptions
    Alternative training
    Wet and melt granulations
    Tablets preparation by direct compression
    Evaluation of solid dosage forms
    Credit test
Literature
    required literature
  • The texts which are available during the lectures. info
    recommended literature
  • European Pharmacopoeia 9. info
  • Handbook of Pharmaceutical Excipients. Great Britain, 2006. ISBN 1-58212-058-7. info
Teaching methods

1Lectures
2Lab training
3 Homework
Assessment methods

1.Written credit test
2.Systematic observation of student during lab training
3.Practical test of student skills
3.Oral examination
Language of instruction
English
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
Teacher's information
Lectures are recommended due to the lack of suitable literature. Students can study this course only after completing the course Dosage Forms and Biopharmacy I
The course is also listed under the following terms Spring 2020, Spring 2021, Spring 2023, Spring 2024, Spring 2025.
  • Enrolment Statistics (Spring 2022, recent)
  • Permalink: https://is.muni.cz/course/pharm/spring2022/FAFO2_13