FaF:FDTMU_FAF Mechanisms of Drug Release and - Course Information

FDTMU_FAF Mechanisms of Drug Release and Their Statistical Evaluation

Extent and Intensity

1/1/0. 25 credit(s). Type of Completion: zk (examination).

Teacher(s)

doc. Mgr. Jan Muselík, Ph.D. (lecturer)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (lecturer)

Guaranteed by

prof. PharmDr. Mgr. David Vetchý, Ph.D.
Faculty of Pharmacy

Prerequisites (in Czech)

FAKULTA(FaF)

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Pharmaceutical Technology (programme FaF, D-FT) (2)
• Pharmaceutical Technology (programme FaF, D-FTA)

Course objectives

Expanding the knowledge of the student focusing on in vitro and in vivo mechanisms of drug release and their statistical evaluation, obtained mainly from world databases containing knowledge from scientific publications especially of foreign research experts and institutions and increasing the ability of the student to process this knowledge into research texts focusing on the content of the study program.

Learning outcomes

After completing the course the student will:
- have theoretical knowledge in the field of dissolution testing - be able to interpret the dissolution profile of a drug from a dosage form - theoretically and practically master the use of mathematical models to infer the kinetics and mechanism of drug release - estimate the effect of polymer blends on drug release - be able to make sophisticated comparisons of dissociation profiles

Syllabus

• Dissolution testing of drug forms
  Modeling and comparison of dissolution profiles
  Mathematical comparison of dissolution profiles
  The effect of polymer blends on the release profiles
  A simple equation for description of solute release - Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs
  Design and evaluation of matrix-based controlled release tablet
  Formulation study and drug release mechanism
  Drug release evaluation
  

Teaching methods

consultation with the teacher

Assessment methods

Oral examination

Language of instruction

Czech

Further comments (probably available only in Czech)

The course can also be completed outside the examination period.
The course is taught each semester.

Teacher's information

Teaching is by way of consultation.
Current literature will be sent to the student by the guarantor upon request.

• Enrolment Statistics (Spring 2025, recent)
  
• Permalink: https://is.muni.cz/course/pharm/spring2025/FDTMU_FAF