Bi9325 Human molecular genetics

Faculty of Science
autumn 2017
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
doc. RNDr. Petr Kuglík, CSc. (lecturer)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
Hana Zelená (assistant)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Mon 18. 9. to Fri 15. 12. Tue 13:00–14:50 B11/305
  • Timetable of Seminar Groups:
Bi9325/01: No timetable has been entered into IS.
Bi9325/02: No timetable has been entered into IS.
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Medical genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of Special biology || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || Bi6088 Bc. state exam Klin.Gen.Diagn. || SOUHLAS)
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the principles of human pharmacogenetics, gene therapy and forensic genetics.
Syllabus
  • Structure and expression of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.
  • Enrolment Statistics (autumn 2017, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2017/Bi9325