E3230 Human Pathophysiology

Faculty of Science
autumn 2021
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer), Mgr. Jan Kučera, Ph.D. (deputy)
Mgr. Bc. Lucie Ráčková, Ph.D. (seminar tutor)
Guaranteed by
prof. MUDr. Julie Dobrovolná, Ph.D.
RECETOX – Faculty of Science
Contact Person: prof. MUDr. Julie Dobrovolná, Ph.D.
Supplier department: RECETOX – Faculty of Science
Timetable
Fri 8:00–9:50 D29/252-RCX1
Prerequisites
BKFY0121c+p a BKFY0122c+p
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the course is to provide a structured overview of the basic processes and concepts of human pathophysiology and related health outcomes, especially in the diseases with strong environmental influences.
Learning outcomes
After the completion of the course, the student will be able to: 1. Describe the general physiological processes used by the body to maintain homeostasis 2. Describe the basic ethiopathogenesis of diseases, including the bodily response to adverse environmental factors 3. Explain the ethiopathogenesis of selected diseases and give the basic definition of the disease 4. Discuss the most important civilization diseases including their mechanisms and possible therapeutic actions.
Syllabus
  • 1. Common disease categories and terminology (characteristics and classification of diseases) 2. Diagnostic methodology (examination, medical history, differential diagnosis, aging and development in the context of diagnostics) 3. Inflammation (definition, mediators, infection, examples of diseases) 4. Basic immunology (basic pathways, mediators, hypersensitivity, autoimmunity, immunodeficiency) 5. Congenital, genetic and chromosomal diseases (causes, definitions, in utero damage, multifactorial inheritance, diagnosis) 6. Transmission of diseases (epidemiology, control of diseases, factors of pathogenicity, antibiotic therapy, viral, bacterial, fungal, parasitic diseases) 7. Naoplasia (etiology, diagnosis, very brief introduction to classification of tumors) 8. Pathogenesis of cardiocirculatory diseases A (vascular diseases, cardiac diseases, coagulation disorders) 9. Pathogenesis of cardiocirculatory diseases B (congestive heart failure, ischemic heart disease, stroke, anemias, disorders of the venous system, lymphatic diseases) 10. Pathogenesis of reproductive diseases (female reproductive disorders, male reproductive disorders, pregnancy-related disorders) 11. Pathogenesis of pulmonary diseases (infectious diseases, obstructive diseases, restrictive diseases – asthma, COPD, carcinoma) 12. Gastrointestinal diseases (hepatic disorders, gastric disorders, intestinal disorders, idiopatic bowel inflammatory disease)
Literature
    required literature
  • NEČAS, Emanuel. Obecná patologická fyziologie. 2. vyd. Praha: Karolinum, 2006, 377 s. ISBN 9788024612911. info
  • FÖLSCH, Ulrich R., Kurt KOCHSIEK and Robert F. SCHMIDT. Patologická fyziologie. Translated by Richard Rokyta - Jiří Mareš. Vyd. 1. české. Praha: Grada, 2003, 586 s. ISBN 802470319X. info
Teaching methods
Education is performed as lectures with Powerpoint presentation. Understanding of mechanisms and consequences is emphasized. Students are frequently asked questions to think about actual topic. They are encouraged to ask questions and be in interaction with the lecturer.
Assessment methods
Attendance of the lectures is not mandatory but strongly recommended for complete understanding of the educated subjects. During the lectures, students are asked about subjects of past lecture. Final assessment (at the end of semester) is by written examination. It is not multiple choice test but 50 questions, which frequently require description, explanation or schematization of asked topic. Questions have 1 - 3 points according to their difficulty. Total count is 100 and to pass at least 30 points are needed.
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is also listed under the following terms Autumn 2019, Autumn 2020, Autumn 2022, Autumn 2023, Autumn 2024.
  • Enrolment Statistics (autumn 2021, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2021/E3230