Bi4090 General microbiology

Faculty of Science
Spring 2025
Extent and Intensity
3/0/0. 3 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
doc. Mgr. Monika Vítězová, Ph.D. (lecturer)
Guaranteed by
doc. Mgr. Monika Vítězová, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: doc. Mgr. Monika Vítězová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Prerequisites
! Bi5710 Microbiology && ! Bi2060 Basic microbiology && !NOW( Bi5710 Microbiology ) && !NOW( Bi2060 Basic microbiology )
Examination from organic chemistry and biochemistry.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Students will be introduced with an overview of main groups of microorganisms - viruses, bacteria (including cyanobacteria), archaea and fungi. The student will understand the content of the following chapters: Structure and function of virus particle. Organization and function of prokaryotic cell. Eukaryotic microorganisms. Microbial growth. Nutritional requirements of microorganisms. Energetic metabolism of chemoorganotrophs, chemolithotrophs and photosynthetic microorganisms. Genetics and molecular biology of microorganisms. Microbial communities. Microorganisms in environment. Exploitation of microorganisms in industry. Main taxonomic groups of bacteria, archea and fungi. Microbial diseases and their control.
Learning outcomes
At the end this course, students should be able to: ;
- understand and explain dissimilarity between prokaryotic and eukaryotic microorganisms ;
- comprehend relationship among microorganisms ;
- elucidate relation amongst microorganisms and environment ;
- document contribution of microorganisms to environmental changes ;
- illustrate use of microorganisms in biotechnology
Syllabus
  • Main groups of microorganisms - viruses, bacteria, archaea and fungi, their phylogenetic position. Prokaryotic microorganisms - bacteria and archaea, prokaryotic cell, significant taxonomic groups and their ecology, motility and chemotaxis of bacteria. Sporulation. Eukaryotic microorganisms - fungi (molds and yeasts) - structure and function of the cell, ecology and significance. Viruses - structure and function of virus particles, life cycle, main important representatives. Microbial nutrition, growth and control - life cycle of prokaryotic cell, growth curve, kinetics of bacterial growth. Influence of environmental factors on growth - temperature, pH, extreme environment, adaptation of microorganisms, antimicrobial agents, antibiotics and mechanisms of their effect, disinfection and sterilization. Metabolism of microorganisms - bacteria and archaea - nutrition and energetic metabolism, anabolism. Nitrogen fixation, methanogenesis, production of secondary metabolites. Metabolism of chemolithotrophs and photosynthetic microorganisms. Genetics and molecular biology of microorganisms - specific characteristics of prokaryotic organisms. Transfer of genetic information by prokaryotic organisms - transformation, conjugation, transduction. Plasmids. Microorganisms in biotechnology and genetic engineering. Quorum sensing. Microorganisms in the environment. Microflora of human body. Microbial diseases and their control. Factors of virulence. Important infection diseases. Microorganisms in agriculture and industry - food, chemical industry, waste management.
Literature
    required literature
  • NĚMEC, Miroslav and Dagmar MATOULKOVÁ. Základy obecné mikrobiologie (Introduction to General Microbiology). 1. vyd. Brno: Masarykova univerzita, 2015, 256 pp. ISBN 978-80-210-7923-6. info
    recommended literature
  • MADIGAN, Michael T., Kelly S. BENDER, Daniel H. BUCKLEY, W. Matthew SATTLEY and David Allan STAHL. Brock biology of microorganisms. Fifteenth edition, global ed. New York: Pearson, 2019, 1058 stran. ISBN 9781292235103. info
  • KUSHKEVYCH, Ivan. Bacterial Physiology and Biochemistry. Cambridge, Massachusetts: Academic Press, 2022, 380 pp. 1st. ISBN 978-0-443-18738-4. Available from: https://dx.doi.org/10.1016/C2022-0-00345-7. URL info
  • VOTAVA, Miroslav. Lékařská mikrobiologie speciální (Medical microbiology special). 1st ed. Brno: NEPTUN, Březová 18, 637 00 Brno, 2003, 495 pp. ISBN 80-902896-6-5. info
Teaching methods
Lecture - Power Point presentations.
Assessment methods
Written examination consisting of 30 questions, each correct answer can earn 1 point, minimal number of points to pass successfully the examination is 18.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses

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Teacher's information
The course content is an overview of the basic knowledge of general and applied microbiology with a focus on the growth, nutrition, metabolism and control of microorganisms and the practical significance and use of microorganisms.
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024.
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