C7878 Biotechnological processes

Faculty of Science
Spring 2025
Extent and Intensity
2/0/0. 4 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
prof. Mgr. Tomáš Kašparovský, Ph.D. (lecturer)
Ing. Matouš Čihák (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
Mgr. Kateřina Dadáková, Ph.D. (lecturer)
Ing. Jan Červený, Ph.D. (lecturer)
Mgr. Jiří Kučera, Ph.D. (lecturer)
Guaranteed by
prof. Mgr. Tomáš Kašparovský, Ph.D.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: Mgr. Jiří Kučera, Ph.D.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Mon 17. 2. to Sat 24. 5. Thu 14:00–15:50 C05/114
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Overview and characterization of selected modern biotechnological processes expanding existing study programs.
Learning outcomes
After completing the course, the student will be able to better understand selected modern biotechnologies utilizing microbial, plant, and animal cell cultures.
Syllabus
  • Microbial Pharmaceutical Biotechnology: Introduction to pharmaceutical production. Selection of production systems. Optimization of fermentation. Separation and purification of intracellular and extracellular products. Drying of fermentation products and final processing. Finalization of obtained products. Biotransformation. Good Manufacturing Practice documentation.
  • Animal Cell Biotechnology: Introduction to animal cells and their characteristics. Potency and differentiation, Hayflick limit, immortalized cell lines, cultivation and differentiation. Use of animal cells for pharmaceutical production. Use of stem cells in drug screening and production. Animal cells and cell therapy. Special applications and future perspectives (3D cultivation, organoids, 3D bioprinting, in vitro tissue and organ substitutes).
  • Plant and Photosynthetic Biotechnology: Introduction to plant cell physiology. Methods for the development of GMO crops, their applications, and risks. Plant-based production of biotechnologically significant compounds. Evolution of photosynthesis and endosymbiosis. Structure of pigments and energy conversion mechanisms. Carbon dioxide fixation and genetic improvement of photosynthesis. Photosynthetic microorganisms and cultivation methods. Optimization of production and control of cultivation processes.
Literature
  • Applied plant cell biology : cellular tools and approaches for plant biotechnology. Edited by Peter Nick - Zdeněk Opatrný. Berlin: Springer, 2014, xiv, 481. ISBN 9783642417863. info
  • Air pollution and plant biotechnology. Edited by P. Bhaskar. 1st ed. Delhi, India: Manglam Publications, 2009, vii, 291 p. ISBN 9788190678537. info
  • Agricultural biotechnology. Edited by Hemant Rawat. Jaipur, India: Oxford Book Co., 2008, 277 p. ISBN 9788189473235. info
  • Advances in biotechnology. Edited by S. N. Jogdand. Rev. ed. Mumbai [India]: Himalaya Pub. House, 2007, 311 p. ISBN 9788183182676. info
  • BARSANTI, Laura and Paolo GUALTIERI. Algae : anatomy, biochemistry, and biotechnology. Boca Raton, Fla.: CRC Press, 2006, 301 s. ISBN 0849314674. info
  • Basic biotechnology. Edited by Colin Ratledge - Bjørn Kristiansen. 3rd ed. Cambridge: Cambridge University Press, 2006, xiv, 666. ISBN 9780521549585. info
Teaching methods
Lectures from selected chapters of modern biotechnology. Discussion on detailed issues.
Assessment methods
Final written exam.
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is also listed under the following terms Autumn 2019, Autumn 2020, autumn 2021, Spring 2023, Spring 2024, Spring 2026.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/sci/spring2025/C7878