LF:aZLFA0621p Pharmacology I - lect. - Course Information

aZLFA0621p Pharmacology I - lecture

Extent and Intensity

1/0/0. 1 credit(s). Type of Completion: z (credit).
In-person direct teaching

Teacher(s)

doc. MUDr. Regina Demlová, Ph.D. (lecturer)
doc. PharmDr. Jan Juřica, Ph.D. (lecturer)
Mgr. Petra Amchová, Ph.D. (lecturer)
doc. RNDr. Ladislava Bartošová, Ph.D. (lecturer)
Mgr. Jana Kubátová, Ph.D. (lecturer)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (lecturer)
MUDr. Jana Pistovčáková, Ph.D. (lecturer)
doc. PharmDr. Jana Rudá, Ph.D. (lecturer)
PharmDr. Jitka Rychlíčková, Ph.D. (lecturer)
Mgr. Barbora Říhová, Ph.D. (lecturer)
PharmDr. Lenka Součková, Ph.D. (lecturer)
Mgr. Kristýna Nosková, Ph.D. (alternate examiner)

Guaranteed by

doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: doc. Mgr. MVDr. Leoš Landa, Ph.D.
Supplier department: Department of Pharmacology – Theoretical Departments – Faculty of Medicine

Prerequisites (in Czech)

aZLPA0521c Pathology I - practice && aZLPF0521c Pathophysiol. I - practice && aZLCP051c Clin. Introd. in Surgery-prac.

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Dentistry (programme LF, M-DENT)
• Dentistry (eng.) (programme LF, M-ZL)

Course objectives

At the end of the course, the student should be able to understand integration in the field of biomedical sciences such as chemistry, physiology, molecular biology, pathology and pathological physiology clarifying mechanisms of drugs effects and under which conditions they may elicit therapeutic, adverse, and toxic effects. Students will be familiar with principles of pharmacovigilance.

Learning outcomes

At the end of the course student will be able:
to understand integration in the field of biomedical sciences such as chemistry, physiology, molecular biology, pathology and pathological physiology clarifying mechanisms of drugs effects and under which conditions they may elicit therapeutic, adverse, and toxic effects, and what is the relation to the dose given and route of administration.
to undertstand the principles of intoxication treatment and issue of drug addiction.

Syllabus

• LECTURES

• Spring semester 2024

• 1^st week
• Historical aspects of pharmacology. Pharmacology - definitions, terminology, subspecializations. The active substance, pharmacon - drug. Effective pharmacotherapy.
• 2^nd week
• Pharmacodynamics. Mechanisms of drug action, non-specific, specific. Receptor and binding sites subtypes, their function.
• 3^rd week
• Drug delivery approaches. Classification of administration routes. Factors related to administration route selection. Characteristic of administration routes. Innovative administration routes.
• 4^th week
• Pharmacokinetics. Drug absorption, distribution, metabolism and elimination. Changes of drug effects after the repeated administration.
• 5^th week
• General principles of poisoning management. Specific antidotes in poisoning therapy. General principles of drug addiction.
• 6^th week
• Drug addiction to the individual substances.
• 7^th week
• Factors affecting drug effects. Influence of accompanying diseases on drugs effects.
• 8^th week
• Glucocorticoids. Natural and synthetic corticosteroids, steroid receptor, mechanism of action, pharmacological use and side effects. Immunomodulatory agents. Treatment of hyper/hypothyroidism.

Literature

required literature
• RITTER, James, R. J. FLOWER, Graeme HENDERSON, Yoon Kong LOKE, David J. MACEWAN and H. P. RANG. Rang and Dale's pharmacology. Ninth edition. Edinburgh: Elsevier, 2020, xvi, 789. ISBN 9780702074486. info
• Selected chapters from general pharmacology for students of general medicine and dentistry at FM MU, https://portal.med.muni.cz/discipline-13-pharmacology

recommended literature
• WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015, xi, 664. ISBN 9781451191776. info

not specified
• Pharmaceutical practice. Edited by Judith A. Rees - Ian Smith - Jennie Watson. 5th ed. Edinburgh: Churchill Livingstone Elsevier, 2014, xvii, 552. ISBN 9780702051432. info

Teaching methods

Students are expected to follow the provided lectures.

Assessment methods

There is no testing of knowledge in this part of study as students are expected to continue pharmacological course in the subsequent semester.

Language of instruction

English

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 15.

Teacher's information

Information for the students:

Termination in the Spring semester: credit.

There is no testing of knowledge in this part of study.

Office hours of the secretariat of the Department of Pharmacology, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00 Brno - Bohunice:

daily 13.00 - 14.00 pm, tel.: 54949 3070.

• Enrolment Statistics (spring 2025, recent)
  
• Permalink: https://is.muni.cz/course/med/spring2025/aZLFA0621p