VLFA08222c Pharmacology II - practice

Faculty of Medicine
spring 2025
Extent and Intensity
0/3/0. 2 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
doc. MUDr. Regina Demlová, Ph.D. (lecturer)
doc. PharmDr. Jan Juřica, Ph.D. (seminar tutor)
Mgr. Barbora Říhová, Ph.D. (lecturer)
Mgr. Petra Amchová, Ph.D. (seminar tutor)
doc. RNDr. Ladislava Bartošová, Ph.D. (seminar tutor)
PharmDr. Adéla Bártová (seminar tutor)
MVDr. Eva Dražanová, Ph.D. (seminar tutor)
Carlos Daniel Ferreira Fonseca, MSc. (seminar tutor)
PharmDr. Tomáš Hammer (seminar tutor)
PharmDr. Mária Hricková (seminar tutor)
Mgr. Petr John (seminar tutor)
Mgr. Jana Kubátová, Ph.D. (seminar tutor)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (seminar tutor)
MUDr. Alena Máchalová, Ph.D. (seminar tutor)
MUDr. Jana Nováková, Ph.D. (seminar tutor)
MUDr. Jana Pistovčáková, Ph.D. (seminar tutor)
doc. PharmDr. Jana Rudá, Ph.D. (seminar tutor)
PharmDr. Jitka Rychlíčková, Ph.D. (seminar tutor)
MUDr. Tomáš Sokop (seminar tutor)
PharmDr. Lenka Součková, Ph.D. (seminar tutor)
Mgr. Nina Zemanová, Ph.D. (seminar tutor)
doc. PharmDr. Ondřej Zendulka, Ph.D. (seminar tutor)
Renata Bláblová (assistant)
MUDr. Filip Šiška (assistant)
Mgr. Marta Vyoralová (assistant)
Guaranteed by
doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Barbora Říhová, Ph.D.
Supplier department: Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Prerequisites (in Czech)
VLFA07212p Pharmacology I
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the course is to acquiant the students with drugs from selected pharmacotherapeutic groups and to learn them how to use the drugs rationally with respect to their mode of action, indications and contraindications.
Learning outcomes
At the end of the course student should be able choose and prescribe suitable drug for the patient with known indicication. The selection will be made with respect to all factors influencing drug safety and efficacy.
Syllabus

  • aVLFA08222c - Pharmacology II practicals

    General medicine

    Spring semester

  • 1. ANTIPSYCHOTICS, ANTIPARKINSONICS
  • Classification of psychotropic medicines. Pharmacology of dopaminergic system with the focus on antipsychotics and antiparkinsonics.
  • 2. ANTIDEPRESSANTS
  • Pharmacological review of antidepressants, cognitive enhancers and psychostimulants.
  • 3. ANXIOLYTICS, HYPNOSEDATIVES, ANTICONVULSANTS
  • GABAergic neurotransmission. Anxiolytics, hypnosedatives, anticonvulsants – modes of action, drugs, indications, AE including the risk of abuse. Rules in the therapy of sleeping disorders and seizures with respect to specific subpopulations. Psychopharmacological case reports.
  • 4. ANAESTHETIC DRUGS
  • Basic pharmacological characteristics of general and local anaesthetic drugs. Premedication prior to general anaesthesia.
  • 5. VASODILATORS
  • TEST No. 1
  • Hypolipidemic drugs, antiobesity drugs, nitrates, Ca channel blockers. Risk factors of cardiovascular disorders. Pharmacotherapy of dyslipidaemia and ischaemic heart disease.
  • 6. DRUGS INFLUENCING RAAS, DIURETICS
  • ACE inhibitors, AT-II receptor antagonists, renin antagonists, diuretics, mineralocorticoid receptor antagonists. Antihypertensives.
  • 7. DRUGS INFLUENCING MYOCYTES
  • Beta-blockers and bradines, positive inotropics, Ca channel blockers - nonDHP, antiarrhythmic drugs. Drugs in heart failure. Summary of cardiovascular drugs.
  • 8. DRUGS INFLUENCING HAEMOSTASIS
  • Classification of drugs interfering with the process of haemostasis, pharmacological review of anticoagulants, antiplatelets, fibrinolytics and antianemics.
  • 9. ANTI-INFECTIVES I - ANTIBIOTICS
  • TEST No. 2
  • Pharmacological review of antibiotics, PK/PD parametres, case reports, bacterial resistance.
  • 10. ANTI-INFECTIVES II – ANTIMYCOTICS AND ANTIVIRALS. DERMATOLOGICS
  • Antibacterial drugs in respiratory infections, UTI and intensive care antibiotics. Dermatologics – classification and pharmacological review, local anti-infectives, drug prescription in dermatology.
  • 11. DRUGS OF GIT
  • PRESCRIPTION TEST
  • Pharmacological review of drugs in GIT diseases.
  • 12. CYTOSTATICS AND TARGETED DRUGS IN ONCOLOGY
  • Overview, classification and mechanisms of action of anticancer drugs. Adverse effects of cytostatics.
  • 13. THERAPY OF INTOXICATIONS
  • Principles of therapy of intoxications. Case reports.
  • 14. DRUG INTERACTIONS
  • TEST No. 3
  • Case reports on drug-drug interactions.
  • 15. PHYTOPHARMACOLOGY
  • Pharmaceutical forms of herbal medicines, herbal tea mixtures preparation and degustation. Drug-drug interactions of herbal medicines. Herbal self-treatment of selected diseases. Credits.
Literature
    required literature
  • RITTER, James, R. J. FLOWER, Graeme HENDERSON, Yoon Kong LOKE, David J. MACEWAN and H. P. RANG. Rang and Dale's pharmacology. Ninth edition. Edinburgh: Elsevier, 2020, xvi, 789. ISBN 9780702074486. info
  • RITTER, James, R. J. FLOWER, Graeme HENDERSON, Yoon Kong LOKE, David J. MacEWAN, Emma ROBINSON, James FULLERTON. Rang and Dale's pharmacology. Tenth edition. Elsevier, 2023. 850 p. ISBN 9780323873956.
    recommended literature
  • RANG, H. P., James RITTER, R. J. FLOWER and Graeme HENDERSON. Rang & Dale's pharmacology. Eighth edition. [Edinburgh]: Churchill Livingstone, 2016, xv, 760. ISBN 9780702053627. info
  • http://search.ebscohost.com/login.aspx?direct=true&db=nlebk&AN=1160493&site=ehost-live&ebv=EB&ppid=pp_cover
  • Farmakologie. Edited by Jan Švihovec - Jan Bultas - Pavel Anzenbacher - Jaroslav Chládek - J. 1. vydání. Praha: Grada Publishing, 2018, xix, 962. ISBN 9788024755588. info
  • Základy speciální receptury léčivých přípravků, Juřica a kol., 2013, http://portal.med.muni.cz/clanek-611-zaklady-specialni-receptury-lecivych-pripravku.html
  • WALLER, Derek, Anthony P. SAMPSON and Andrew W. HITCHINGS. Medical pharmacology and therapeutics. Sixth edition. London: Elsevier, 2022, vii, 742. ISBN 9780702081590. info
  • Markova farmakoterapie vnitřních nemocí. Edited by Josef Marek - Michal Vrablík. 5., zcela přepracované a d. Praha: Grada, 2019, xxiv, 868. ISBN 9788024750781. info
    not specified
  • Elektronická skripta: https://portal.med.muni.cz/disciplina-13-farmakologie
  • Knihovna kazuistik: https://is.muni.cz/auth/do/med/el/case_reports/index.html
  • Atlas léčivých rostlin, https://is.muni.cz/auth/do/med/el/lecive_rostliny/atlas.html
Teaching methods
Drug classes from the syllabus are actively reviewed by students and supported by the teacher. Possible ambiguities are discussed and learned knowledge is practised in case reports from real clinical practice. The training of drug prescription with the use of drug compendia and the computer databases.
Assessment methods
The participation in practicals is obligatory and registered. Students can miss two classes without excuse. To get credits a students have to pass 4 written tests:
Prescription test
2 RMP, the indication or pharmacotherapeutic gorup is stated together with a basic data of the patient significant for correct drug selection
3 Multiple-choice tests
15 questions, number of correct answers indicated, minimal score to pass 6 points. One of the tests can be repeated once.
The credits will be given to students who: passed the prescription test and scored at least 6 points from each of multiple-choice tests and their total score from these tests is at least 20 points.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 45.
Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024.
  • Enrolment Statistics (spring 2025, recent)
  • Permalink: https://is.muni.cz/course/med/spring2025/VLFA08222c