LF:aZLFA0621p Farmakologie I - přednáška

aZLFA0621p Farmakologie I - přednáška

Lékařská fakulta
jaro 2020

Rozsah

1/0/0. 30. 0 kr. Ukončení: z.

Vyučující

Garance

doc. MUDr. Regina Demlová, Ph.D.
Farmakologický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: doc. MUDr. Regina Demlová, Ph.D.
Dodavatelské pracoviště: Farmakologický ústav – Teoretická pracoviště – Lékařská fakulta

Předpoklady

aZLPA0521c Patologie I - cvičení && aZLPF0521c Patol. fyziologie I - cv. && aZLCP051c Chirurgická propedeutika -cv.

Omezení zápisu do předmětu

Předmět je určen pouze studentům mateřských oborů.

Mateřské obory/plány

Zubní lékařství (angl.) (program LF, M-ZL)
Zubní lékařství (program LF, M-ZL)

Cíle předmětu

At the end of the course student should be able to understand integration in the field of biomedical sciences such as chemistry, physiology, molecular biology, pathology and pathological physiology clarifying mechanisms of xenobiotic (including drugs) effects and under which conditions they and their combinations may elicit therapeutic, adverse, and toxic effects, and what is the relation to the dose given, administration route, status of the organism (differences in pediatrics and geriatrics). They will be familiar with the requirements of "Good Clinical Practice" for development of new drugs, and duties of physicians in cooperation with the pharmaceutical industry and principles of pharmacovigilance.

Výstupy z učení

At the end of the course student will be able:
- to understand integration in the field of biomedical sciences such as chemistry, physiology, molecular biology, pathology and pathological physiology clarifying mechanisms of xenobiotic (including drugs) effects and under which conditions they and their combinations may elicit therapeutic, adverse, and toxic effects, and what is the relation to the dose given, administration route, status of the organism (differences in pediatrics and geriatrics).
- be familiar with the requirements of "Good Clinical Practice" for development of new drugs, and duties of physicians in cooperation with the pharmaceutical industry and principles of pharmacovigilance.

Osnova

LECTURES
Spring semester 2020
1^st week
Historical aspects of pharmacology. Pharmacology — definitions, terminology, subspecializations. The active substance, pharmacon - drug. Effective pharmacotherapy.
2^nd week
Mechanisms of drug action, non-specific, specific. Receptor and binding sites subtypes, autoreceptors, heteroreceptors, their function.
3^rd week
Basic principles of Pharmacokinetics. Drug absorption, distribution, metabolism and elimination. Changes of drug effects after the repeated administration.
4^th week
Adverse drug effects. Physiological and pathological factors influencing drug effects. Influence of concomitant diseases on drug effect, polypragmasia.
5^th week
Specificities of pharmacotherapy in pediatric population and in elderly.
6^th week
General principles of poisoning management. Specific antidotes in poisoning therapy.
7^th week
Types of addiction, therapy of substance abuse.
8^th week
Drug interactions at different levels. Assessment of their seriousness.

Literatura

povinná literatura

RANG, H. P., James RITTER, R. J. FLOWER a Graeme HENDERSON. Rang & Dale's pharmacology. Eighth edition. [Edinburgh]: Churchill Livingstone, 2016, xv, 760. ISBN 9780702053627. info
http://search.ebscohost.com/login.aspx?direct=true&db=nlebk&AN=1160493&lang=cs&site=ehost-live

doporučená literatura

http://portal.med.muni.cz/article-491-practicals-in-pharmacology.html
WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015, xi, 664. ISBN 9781451191776. info

neurčeno

Pharmaceutical practice. Edited by Judith A. Rees - Ian Smith - Jennie Watson. 5th ed. Edinburgh: Churchill Livingstone Elsevier, 2014, xvii, 552. ISBN 9780702051432. info
Waller, Derek - Renwick, Andrew G. - Hillier, Keith. Medical pharmacology and therapeutics. 3rd ed. New York : Elsevier Saunders, 2009. ix, 744 p. ISBN 0-7020-2991-2.
Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8

Výukové metody

According to schedule given students are expected to attend lectures read by habilitated pharmacology teacher.

Metody hodnocení

There is no testing of knowledge in this part of study as students are expected to continue pharmacological course in the subsequent semester.

Vyučovací jazyk

Angličtina

Informace učitele

Informace pro studenty studující v češtině:

V jarním semestru je předmět ukončen zápočtem. Požadavky k získání zápočtu - viz ZLFA0621c.
Po získání zápočtu studenti přechází do pokračující výuky v dalším semestru bez povinnosti ověření znalostí v tomto semestru.
Úřední hodiny sekretariátu Farmakologického ústavu LF MU, Kamenice 5, 625 00 Brno - Bohunice:
denně 13.00 - 14.00 hod, tel.: 05-4949 3070.

Information for the students studying in English:

In spring semester is subject of the terminated credit. Requirements for obtaining credit - see ZLFA0621c.
There is no testing of knowledge in this part of study as students are expected to continue pharmacological course in the subsequent semester.
Office hours of the secretariat of the Department of Pharmacology, Faculty of medicine, Masaryk University, Kamenice 5, 625 00 Brno - Bohunice:
daily 13.00 - 14.00 pm, tel.: 05-4949 3070.

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Studijní materiály
Předmět je vyučován každoročně.
Výuka probíhá každý týden.

Předmět je zařazen také v obdobích jaro 2018, jaro 2019, jaro 2021, jaro 2022, jaro 2023, jaro 2024, jaro 2025.

Statistika zápisu (jaro 2020, nejnovější)
Permalink: https://is.muni.cz/predmet/med/jaro2020/aZLFA0621p

LF:aZLFA0621p Farmakologie I - přednáška - Informace o předmětu

aZLFA0621p Farmakologie I - přednáška

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