aVLPF0622c Pathophysiology II - practice

Lékařská fakulta
jaro 2021
Rozsah
0/3/0. 45. 3 kr. Ukončení: z.
Vyučující
MUDr. Vendula Bartáková, Ph.D. (cvičící)
MUDr. Kamil Ďuriš, Ph.D. (cvičící)
doc. MUDr. Jaromír Gumulec, Ph.D. (cvičící)
Ing. Hana Holcová Polanská, Ph.D. (cvičící)
Mgr. Katarína Chalásová, Ph.D. (cvičící)
MUDr. Michal Jurajda, Ph.D. (cvičící)
prof. MUDr. Kateřina Kaňková, Ph.D. (cvičící)
Mgr. Andrea Knight, Ph.D. (cvičící)
MUDr. Jan Máchal, Ph.D. (cvičící)
prof. RNDr. Michal Masařík, Ph.D. (cvičící)
MUDr. Stanislav Matoušek, Ph.D. (cvičící)
MUDr. Petr Müller, Ph.D. (cvičící)
Mgr. Lukáš Pácal, Ph.D. (cvičící)
prof. RNDr. Monika Pávková Goldbergová, Ph.D. (cvičící)
Mgr. Jana Šístková, Ph.D. (cvičící)
MUDr. Michal Šitina, Ph.D., M.Sc. (cvičící)
prof. MUDr. Anna Vašků, CSc. (cvičící)
Věra Ježková (pomocník)
Mgr. Šárka Lakomá (pomocník)
Mgr. Lucie Válková, Ph.D. (pomocník)
Garance
prof. MUDr. Kateřina Kaňková, Ph.D.
Ústav patologické fyziologie – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: prof. MUDr. Kateřina Kaňková, Ph.D.
Dodavatelské pracoviště: Ústav patologické fyziologie – Teoretická pracoviště – Lékařská fakulta
Rozvrh seminárních/paralelních skupin
aVLPF0622c/30: Čt 13:00–15:30 A18/112, M. Jurajda, J. Máchal
aVLPF0622c/31: Čt 13:00–15:30 A18/112, M. Jurajda, J. Máchal
aVLPF0622c/32: St 14:00–16:30 A18/112
aVLPF0622c/33: St 14:00–16:30 A18/112
aVLPF0622c/34: Út 10:00–12:30 A18/112
aVLPF0622c/35: Út 10:00–12:30 A18/112
aVLPF0622c/36: Po 13:00–15:30 A18/112, M. Jurajda, J. Máchal
aVLPF0622c/37: Po 13:00–15:30 A18/112, M. Jurajda, J. Máchal
Předpoklady
aVLPF0521c Pathophysiology I - practice && aVLBC0422p Biochemie II - předn. && aVLFY0422p Fyziologie II - přednáška
Fyziologie, biochemie
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
The objective of the practical exercises and seminars from pathological physiology is to provide students basic idea about pathological states and experimental work. Students will also acquire practical skills necessary for their subsequent(future) study and work.
Výstupy z učení
Student will explain the pharmacological options affecting the secretion of gastric juice in the context of experimentally induced gastric ulcer in experimental animal model (inhibition of proton pump, H2 receptor blockade);
Student will explain the pharmacological options affecting the secretion of gastric juice in the context of experimentally induced gastric ulcer in experimental animal model (inhibition of proton pump, H2 receptor blockade);
Student demonstrates the principle of load test (oGTT) in an animal model of experimentally induced diabetes (alloxan);
Student shall identify clinically relevant parameters describe nutritional status (calorimetry, BMI, WHR index, the weight, the skin-fold thickness, bioimpedance, DEXA) ;
Student demonstrates the examination of the quality of the skin barrier, through the examination of resistance and conductivity of the skin or a chemical (Burckhardt´s) examination with regard to the composition of the skin barrier;
Student demonstrates onset of obstruction icterus induced by ligation of ductus choledochus. He understands etiopathogenesis of other types of icterus (hemolytic, hepatic) and diagnostics of them using heme metabolites in urine, blood and stool using mitochondrial/cytoplasmatic membranes liver enzymes;
Student describes etiopathogenesis of venous thrombosis using data from experimental animal model;
Student will explain the importance and principles of DNA d iagnostics to detect I/D polymorphism using PCR methodology ACE
Osnova
  • Pathophysiology of GIT (tutorial). Exp. induced diabetes mellitus preparation. Exp. induced diabetes mellitus – diagnosis by glucose tolerance test Overview of molecular biology exp. methods used in pathophysiology (tutorial & demonstration of selected lab. methods) Obstructive jaundice I - preparation Exp. induced jaundice in lab. animal Radiation Radiation II, haematological microscopy Haematology, blood transfusion (tutorial) Exp. induced changes of blood flow in splanchnic region in experimental animal Exp. induced vein thrombosis Anaphylactic reaction, pathophysiology of circulatory shock (tutorial) Statistical evaluation of experiments (advanced methods), practical analysis of exp. data (using stat. software) Neuropathophysiology I - – cerebrovascular disorders, intracranial hypertension (bleeding, liquor, …) (tutorial) Pathophysiology of skin disorders
Literatura
Výukové metody
practical exercises in lab, seminars
Metody hodnocení
Practicals are compulsory (the only permited reason for not attending is a student's sick leave). Students can be given written tests or individual home work by tutor's throughout the term. Student's participation in the practicals throughout the term is certified by a credit given upon the following conditions: (i) complete attendance, (ii) complete protocols from the exp. practicals, (iii) indicidual criteria announced by the principal tutor.
Vyučovací jazyk
Angličtina
Informace učitele
http://www.med.muni.cz/patfyz/patfyzc.html
Students have to be wearing lab coats during the practicals and follow the safety rules when working experimentally. Student can - with tutor's approval - substitute the particular practical in a given week with another group in case he/she has a justifiable reason for it.
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Studijní materiály
Předmět je vyučován každoročně.
Nachází se v prerekvizitách jiných předmětů
Předmět je zařazen také v obdobích jaro 2018, jaro 2019, jaro 2020, jaro 2022, jaro 2023, jaro 2024, jaro 2025.