VSFY0321s Physiology tutorial

Faculty of Medicine
Autumn 2005
Extent and Intensity
0/1/0. 4 credit(s). Type of Completion: z (credit).
Teacher(s)
MUDr. Mohamed Al-Kubati, CSc. (seminar tutor)
prof. MUDr. Marie Nováková, Ph.D. (seminar tutor)
MUDr. Zuzana Nováková, Ph.D. (seminar tutor)
doc. MUDr. Robert Roman, Ph.D. (seminar tutor)
doc. MUDr. Zdeněk Wilhelm, CSc. (seminar tutor)
MUDr. Bc. Eva Závodná, Ph.D. (seminar tutor)
Guaranteed by
prof. MUDr. Bohumil Fišer, CSc.
Department of Physiology – Theoretical Departments – Faculty of Medicine
Prerequisites (in Czech)
VSLC011p Med.Chem.- lecture && VSBI0222p Biology II - lecture && ( STBF011p Biophysics || VLBF011p Biophysics ) && VSBC0221s Biochemistry I-sem.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Syllabus
  • Program of TUTORIAL I: Intercellular contact Mechanical, electrical and humoral coupling, ligands and receptors. Second messengers. Resting membrane potential Na/K ATP-ase, diffusion currents, electro-chemical gradient, equilibrium potential. Physiological importance of resting membrane potential. Action potential Local responses, selective conductivity of membrane channels, mechanism of depolarization, transpolarization and repolarization. Principles of muscle contraction Contractile proteins, troponin and tropomyosin, role of calcium, mechanism of relaxation. Differences between smooth, skeletal and heart muscle. Program of TUTORIAL II: Interpretation of the ECG curve a) Electric field of the heart as a vector ( source, determinants, projection on the body surface ) b) Limb and chest leads ( bipolar, unipolar ) c) Construction of the mean electrical axis of the heart ( Eindhoven triangle, paralelogram ) d) Diagnostic value of ECG Cardiac cycle a) Phases of cardiac cycle and their time course ( polygram, intracardiac pressures, heart volume, heart sounds ) b) Phases of cardiac cycle in pressure / volume representation ( effect of changes in preload and afterload ) Autoregulation of cardiac functions a) Starling principle b) Effect of frequency on contractility c) Effect of frequency on the duration of action potential ( Q-T interval ) Program of TUTORIAL III: Heart as a muscle a) Cardiac contractility and its measurement b) Stroke scheme, cardiac output, ejection fraction c) Cardiac energetics Coronary circulation a) Anatomy and functional features ( specialties ) b) Regulation of coronary flow c) Coronary reserve and ischaemic heart disease Rheology ( of blood circulation ) a) Resistance and capacitance vessels b) Poisseuiles law, Laplaces law c) Blood pressure in separate ( different ) parts of blood circulation Program of TUTORIAL IV: Immune mechanisms 1) Development of the immune system. T lymphocytes, B lymphocytes, memory T and B cells, antigen presenting cells. Clones. 2) Cellular immunity. Major histocompatibility complex. NK cells, T4 helper cells, T8 killer cells, T8 suppressor cells. 3) Humoral immunity. Immunoglobulins IgG, IgA, IgM, IgE. 4) The complement system. C1 - C9. Properdin. 5) Lymphokines and cytokines. IL 1, IL 2, IL 3. Colony stimulating factors, GM - CSF. Interferons. Tumor necrosis factor.
Assessment methods (in Czech)
Účast na 4 seminářích v zimním a na 4 v letním semestru je předpokladem k udělení zápočtu. Znalosti z praktické výuky jsou důležitou součástí i ústní zkoušky!!!
Language of instruction
Czech
Further comments (probably available only in Czech)
Information on completion of the course: Absolvování seminářů je podmínkou k udělění zápočtu.
The course is taught annually.
The course is taught: in blocks.
The course is also listed under the following terms Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015.
  • Enrolment Statistics (Autumn 2005, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2005/VSFY0321s