LF:aVLBI0121c Biology I - pract.

aVLBI0121c Biology I - practice

Faculty of Medicine
Autumn 2017

Extent and Intensity

0/3/0. 3 credit(s). Type of Completion: z (credit).

Teacher(s)

Guaranteed by

prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

aVLBI0121c/30: Thu 7:30–10:00 B07/214
aVLBI0121c/31: Mon 12:30–15:00 B07/214
aVLBI0121c/32: Fri 10:10–12:40 B07/214
aVLBI0121c/33: Tue 8:30–11:00 B07/214
aVLBI0121c/34: Thu 15:00–17:30 B07/214
aVLBI0121c/35: Tue 14:20–16:50 B07/214
aVLBI0121c/36: Wed 13:40–16:10 B07/214
aVLBI0121c/37: Wed 8:00–10:30 B07/214
aVLBI0121c/38: Mon 9:50–12:20 B07/214
aVLBI0121c/39: Mon 15:10–17:40 B07/214

Prerequisites

Knowledge of high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_ENG.qwarp) or similar is required.

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

General Medicine (eng.) (programme LF, M-VL)
General Medicine (programme LF, M-VL) (2)

Course objectives

The main objectives of the course are:
- learning to operate the light microscope while observing prokaryotic and eukaryotic cells and various cell structures and processes
- understanding the methods of risk evaluation for monogenic hereditary diseases with autosomal inheritance in patients based on family anamneses

Learning outcomes

After completing the course the student will be able to:
- operate the light microscope
- perform some of the basic cytochemical staining techniques in observation of bacterial and human cells
- explain the basic principles and use of electron microscopy
- describe the basic techniques and applications of tissue and cell cultures
- deduce the impact of selected DNA mutations on the primary structure of proteins
- explain the methodology of assembling and examining the karyotype and its use, and to evaluate basic numerical and structural aberrations in assigned human karyotypes
- evaluate the risk of numerical and structural aberrations resulting from meiotic non-disjunctions and chromosomal translocations
- evaluate the risk of monogenic hereditary diseases with autosomal inheritance in patients based on assigned family anamneses of the diseases

Syllabus

Week 1: Instructions. Non-cellular organisms and infectious agents
Week 2: Prokaryotic cells and their medical significance
Week 3: Microscopic observation of eukaryotic cells
Week 4: In vitro culture of human cells - significance for medical research
Week 5: Plasma membrane - osmosis, cell fusion
Week 6: Principles of electron microscopy, cellular ultrastructure
Week 7: DNA structure and replication. Control test 1 (knowledge of the weeks 1 to 6 - lectures, seminars, practices)
Week 8: Transcription and translation
Week 9: Methods of cell cycle studying
Week 10: Mitosis observation under light microscope
Week 11: Biological significance of meiosis - gametogenesis
Week 12: Human karyotype and chromosomal abnormalities
Week 13: no practice - dissection week
Week 14: Genetic disorders - autosomal inheritance Control test 2 (knowledge of the weeks 7 to 13 - lectures, seminars, practices)

Literature

required literature

Actual protocols for practices are provided in electronic form in the Information System of the Masaryk University (IS): Study Materials of the course aVLBI0121c

Teaching methods

laboratory practice, class discussion

Assessment methods

Practical classes are mandatory.
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed 2 written control tests during the semester. In case you do not pass one of the control tests and its re-sit, you have to pass the final test (so-called Credit test) based on knowledge of the entire semester lectures, seminars and practices.
In case of student’s late arrival to the practice or poor activity at the practice, student is required to write an essay in the length of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices (excused or unexcused). Find the instructions for essay writing in the Course-related instructions in the IS.
In case of 3 absences, (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced to the Information System), it is addressed individually and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
In case of 4 or more unexcused absences, course-unit credit is not awarded.

Language of instruction

English

Follow-Up Courses

Further comments (probably available only in Czech)

The course is taught annually.

Listed among pre-requisites of other courses

Teacher's information

https://is.muni.cz/auth/el/1411/podzim2017/aVLBI0121c/index.qwarp

The course is also listed under the following terms Autumn 2015, Autumn 2016, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.

Enrolment Statistics (Autumn 2017, recent)
Permalink: https://is.muni.cz/course/med/autumn2017/aVLBI0121c

LF:aVLBI0121c Biology I - pract. - Course Information

aVLBI0121c Biology I - practice

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