aBFBI011 Biologie

Lékařská fakulta
podzim 2020
Rozsah
2/0/0. 30. 3 kr. Ukončení: zk.
Vyučující
Mgr. Kateřina Straková, Ph.D. (přednášející)
Ing. Lívia Eiselleová, Ph.D. (přednášející)
prof. MUDr. Iva Slaninová, Ph.D. (přednášející)
Mgr. Kateřina Cetkovská, Ph.D. (přednášející)
Mgr. Kateřina Francová, Ph.D. (přednášející)
prof. RNDr. Ondřej Slabý, Ph.D. (přednášející)
Jana Růžičková (pomocník)
Garance
prof. MUDr. Iva Slaninová, Ph.D.
Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: Mgr. Kateřina Straková, Ph.D.
Dodavatelské pracoviště: Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Rozvrh
Pá 13:00–14:50 B11/211
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
The main objectives of the course are:
- understanding the chemical composition, structure and properties of the main cellular components
- understanding the basic processes in the cell, and understanding the principles of pathology of these processes in cancer and genetic diseases
- understanding the basic principles of heredity
Výstupy z učení
After completing the course the student will be able to:
- describe the composition, structure and functions of prokaryotic and eukaryotic cells
- Explain the principles of intercellular communication and cell differentiation
- Explain the principles of regulation and purpose of cell division (mitosis and meiosis)
- explain basic principles of heredity and nature of human genetic diseases, describe basic methods of gene diagnostics
- Explain the principles of tumour transformation
Osnova
  • Week 1: Introduction. Basic properties of living organisms. Proteins and their functions
  • Week 2: Bacteria and viruses. Human microbiome
  • Week 3: Architecture and functions of eukaryotic cells, biomembranes
  • Week 4: Nucleic acids. Structure of chromosomes. DNA replication
  • Week 5: From genes to proteins – expression of genetic information. Transcription and translation
  • Week 6: Cell signalling. Cell differentiation. Stem cells
  • Week 7: Cytoskeletal system of cells and principles of cell organization in tissues
  • Week 8: Cell cycle and mitosis, regulation of cell division
  • Week 9: DNA damage and repair, cell death
  • Week 10: Meiosis and gametogenesis. Genetics I - karyotype, chromosomal aberrations
  • Week 11: Genetics II - principle of dominance and recessivity, Mendelian and non-Mendelian inheritance
  • Week 12: Methods of gene studying. Gene diagnostics, gene therapy
  • Week 13: Malignant transformation of cells. Cancer
  • Week 14: substitution lecture
Literatura
    doporučená literatura
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014, xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013, 1 online r. ISBN 9781118689028. info
Výukové metody
lecture and class discussion
Metody hodnocení
The course is completed with a written examination test. The test comprises of 30 questions: 15 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 15 given terms for a written explanation. At least 15 points out of 30 are needed to pass. The exam tests the understanding of the discussed knowledge.
The exam requires knowledge of high-school biology at the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_ENG.qwarp) or similar, and the knowledge discussed at the lectures.
Vyučovací jazyk
Angličtina
Navazující předměty
Informace učitele
https://is.muni.cz/auth/el/1411/podzim2017/aBFBI011/index.qwarp
All important information about the course organisation, study material, etc. you can find in the Interactive syllabus of the course: https://is.muni.cz/auth/el/1411/podzim2017/aBFBI011/index.qwarp.
In case of any lack of understanding from the lectures we recommend to study the recommended textbooks at the extent of the syllabus or come to discuss the problem in the consulting hours.
Další komentáře
Předmět je vyučován každoročně.
Předmět je zařazen také v obdobích podzim 2015, podzim 2016, podzim 2017, podzim 2018, podzim 2019, podzim 2021.