VLPF0521p Patholphysiology I - lecture

Faculty of Medicine
autumn 2023
Extent and Intensity
2/0/0. 2 credit(s). Type of Completion: z (credit).
Teacher(s)
prof. MUDr. Kateřina Kaňková, Ph.D. (lecturer)
prof. MUDr. Anna Vašků, CSc. (lecturer)
prof. RNDr. Monika Pávková Goldbergová, Ph.D. (lecturer)
prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
doc. RNDr. Sabina Ševčíková, Ph.D. (lecturer)
MUDr. Jan Máchal, Ph.D. (lecturer)
Bc. Lenka Hladíková (assistant)
Mgr. Katarína Chalásová, Ph.D. (assistant)
Mgr. Lukáš Pácal, Ph.D. (assistant)
Guaranteed by
prof. MUDr. Kateřina Kaňková, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: prof. MUDr. Kateřina Kaňková, Ph.D.
Supplier department: Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Timetable
Mon 16. 10. to Fri 27. 10. Wed 12:40–14:20 B22/116 aula, Mon 6. 11. to Fri 22. 12. Wed 12:40–14:20 B22/116 aula, Mon 18. 9. to Fri 6. 10. Wed 12:40–14:20 B22/116 aula; and Wed 11. 10. 12:40–14:20 B11/114, Wed 1. 11. 13:30–15:10 B22/116 aula
Prerequisites (in Czech)
( VLFY0422p Physiology II - lecture || VSFY0422p Physiology II - lecture ) && ( VSBC041p Biochemistry II -l || VLBC0422p Biochemistry II - lecture ) && ( VLAN0222p Anatomy II l || VSAN0333p Anatomy III - lec. ) && ( VLHE0322p Histology and embryology II -l || VSHE0322p Histology and embryology II -l ) && VLLM0421c Med.Microbiol.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the subject is to train medical students in preclinical thinking with a focus on etiology and pathogenesis of diseases and its dynamics in the context of organ system pathophysiology as well as general pathophysiology incl.: • Pathophysiology of cardiovascular system. • Pathophysiology of digestive system, nutrition deficits. • Pathophysiology of endocrine system, metabolic diseases. • Pathophysiology of hemopoietic system, neoplasias. • Rheumatic diseases. Immunologically conditioned diseases. • Pathophysiology of respiratory tract. • Pathofphysiology of kidneys, disturbances in metabolism of water and ions. • Pathophysiology of nervous system. • Pathophysiology of muscles and sensory organs.
Learning outcomes
Student discusses the etiopathogenesis of atherosclerosis at the molecular, cellular and tissue level • Student will describe the etiopathogenesis of systolic and diastolic dysfunction of myocardium and pressure and volume overload of the heart • Student distinguishes between the causes of arrhythmias • Student categorizes the clinical forms of ischemic heart disease and clinically important consequences of heart failure syndrome • Student will explain the general and special pathophysiology of shock conditions and basic types of shock • Student will sum up the most common causes of disorders of the respiratory apparatus • Student characterizes the pathophysiology of chronic bronchitis and pulmonary emphysema • Student will sum up the pathogenesis of respiratory insufficiency • Student controls the issue of regulation of renal perfusion • Student can explain the issue glomerulopathy • Student categorizes causes of acute and chronic renal failure • Student will explain the difference between acute and chronic effects of hormones • Student categorizes acute and chronic renal failure • Student will explain the difference between acute and chronic effects of hormones • Student discusses the pathophysiology of clinically significant endocrine disruption of the function • Student will describe the pathophysiology of clinically significant gastrointestinal disorders, from a clinical point of view • Student will describe the anemic syndrome including the effects of anemic hypoxia • Student discusses different classification of anemias • Student discusses the pathophysiological aspects of transfusion of blood and blood derivatives, • Student will describe the main categories of diseases of white blood cells • Student distinguishes principled differences between physiological and pathological blood clotting • Student discusses the most important hypocoagulation and hypercoagulation disorders • Student will sum up the etiopathogenesis of common diseases of the joints, • Student demonstrates a knowledge of the etiopathogenesis of diseases of the muscle and neuromuscular plate • Student rattles off examples of failures of a sensory sensation • Student demonstrates examples of common neurodegenerative diseases of CNS • Student discusses the pathophysiology of epilepsy, • Student will use knowledge of the composition of cerebrospinal fluid • Student argues the importance of stability of intracranial pressure and its components for the creation of intracranial hypertension • Student will sum up the function of autonomous (vegetative) system • Student will sum up the function of movement system and consequences of its failure • Student describes the systems important for the existence of consciousness and waking
Syllabus
  • Detailed syllabus is attached in IS as a pdf file.
Literature
    required literature
  • NEČAS, Emanuel a spol. Obecná patologická fyziologie. 1. vyd. Praha: Karolinum, 2000, 377 pp. ISBN 80-246-0051-X. info
  • NEČAS, Emanuel. Patologická fyziologie orgánových systémů. 1. vyd. Praha: Karolinum, 2003, 379 s. ISBN 9788024606750. info
  • NEČAS, Emanuel. Patologická fyziologie orgánových systémů. 1. vyd. Praha: Karolinum, 2003, s. 381-760. ISBN 9788024606743. info
  • Ivan Damjanov: Pathophysiology, ISBN 13: 978-1-4160-0229-1, Saunders Elsevier, 2009.
    recommended literature
  • PÁVKOVÁ GOLDBERGOVÁ, Monika. Patofyziologie v obrazech. Vydání první. Brno: Masarykova univerzita, 2016, 186 stran. ISBN 9788021083233. info
Teaching methods
lecture
Assessment methods
Pathophysiology course is finalised by an oral exam. Student will select questions from 4 different topics and he/she is given time to prepare answers (up to 120 min). Following topics will be represented by 1 question in oral exam: • Set P: practicals • Set G: general pathophysiology • Set S1: circulatory, respiratory, excretory and nervous system pathophysiology • Set S2: gastrointestinal, endocrine, hematopoietic and musculoskeletal system pathophysiology • Study materials include practical tutorials, recommended literature and handouts provided for lectures. Results/cumulative number of points obtained in tests can be taken into account by examiner for final grade.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 30.
Teacher's information
http://www.med.muni.cz/patfyz
Lectures are held in UKB lecture hall B22/116 every Wednesday 12:40-14:20. All lecturers will provide study material via IS. Looking forward to meeting you and working together!
The course is also listed under the following terms Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2024.
  • Enrolment Statistics (autumn 2023, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2023/VLPF0521p