F1FT1_14 Pharmacology I

Faculty of Pharmacy
Spring 2024
Extent and Intensity
3/3/0. 7 credit(s). Type of Completion: z (credit).
Teacher(s)
doc. PharmDr. Peter Kollár, Ph.D. (lecturer)
doc. PharmDr. Jan Juřica, Ph.D. (lecturer)
PharmDr. Tereza Kauerová, Ph.D. (lecturer)
doc. PharmDr. Peter Kollár, Ph.D. (seminar tutor)
PharmDr. Tereza Kauerová, Ph.D. (seminar tutor)
PharmDr. Zuzana Široká, Ph.D. (seminar tutor)
MVDr. Renata Blechová, Ph.D. (seminar tutor)
Guaranteed by
doc. PharmDr. Peter Kollár, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Supplier department: Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Timetable
Fri 23. 2. to Fri 29. 3. Fri 8:00–10:30 44-056, Fri 10. 5. to Fri 24. 5. Fri 8:00–10:30 44-056; and Fri 5. 4. 10:30–13:00 44-056, Fri 12. 4. 8:00–10:30 44-056, Fri 19. 4. 10:30–13:00 44-056, Fri 26. 4. 11:30–14:00 44-056, Fri 3. 5. 10:30–13:00 44-056
  • Timetable of Seminar Groups:
F1FT1_14/01: Mon 19. 2. to Fri 12. 4. Tue 7:45–10:15 44-056, Mon 15. 4. to Fri 26. 4. Tue 7:45–10:15 45-135, Mon 29. 4. to Fri 24. 5. Tue 7:45–10:15 44-056
F1FT1_14/02: Mon 19. 2. to Fri 12. 4. Tue 10:30–13:00 44-056, Mon 15. 4. to Fri 26. 4. Tue 10:30–13:00 45-135, Mon 29. 4. to Fri 24. 5. Tue 10:30–13:00 44-056
F1FT1_14/03: Mon 19. 2. to Fri 17. 5. Thu 7:30–10:00 45-135; and Thu 23. 5. 7:30–10:00 44-037
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
The capacity limit for the course is 160 student(s).
Current registration and enrolment status: enrolled: 122/160, only registered: 0/160, only registered with preference (fields directly associated with the programme): 0/160
fields of study / plans the course is directly associated with
Course objectives
Pharmacology is a science that studies interactions of medical substances and organisms on various morphological and physiological levels. It focuses on mechanisms and time progress of medicines in organisms (pharmacokinetics), and on medicines impact mechanisms on an organism (pharmacodynamics). Certain toxicology sections (science on toxins) constitute a part of the pharmacology in the area of undesirable effects as well.

Learning outcomes
After completing the course the student is able to clarify the basic general rules regarding the fate of the drug in the body and the mechanisms of the drug's effect on the human body. Student can also define and characterize the properties of specific drugs - mechanisms of action, pharmacological effects, pharmacokinetic properties, side effects and interactions. The student will be able to apply the acquired knowledge about the properties of drugs in a safe and effective pharmacotherapy.
Syllabus
  • Lectures spring 2024: Pharmacology I
    Friday 8:00 - 10:30

  • 1st week: 23. 2. 2024
    Pharmacokinetic processes

  • 2nd week: 1. 3. 2024
    Pharmacokinetic parameters

  • 3rd week: 8. 3. 2024
    Receptor theory. Types of receptors

  • 4th week: 15. 3. 2024
    Basic pharmacodynamic processes (Dose-drug relationship. Intercellular signaling. Drug-receptor interaction)

  • 5th week: 22. 3. 2024
    Pharmacology of the autonomic nervous system

  • 6th week: 29. 3. 2024
    Easter – Good Friday (public holiday)

  • 7th week: 5. 4. 2024
    General principles of poisoning therapy. Drug addictions (classification, mechanisms of origin, possibilities of therapy)

  • 8th week: 12. 4. 2024
    Factors influencing the effect of a drug

  • 9th week: 19. 4. 2024
    Drugs used in pain therapy (opioid and non - opioid analgesics)

  • 10th week: 26. 4. 2024
    Introduction to CNS pharmacology (CNS neurotransmitters. Classification of psychotropic drugs.)

  • 11th week: 3. 5. 2024
    CNS pharmacology

  • 12th week: 10. 5. 2024
    Antiepileptic drugs. Drugs in Parkinson´s disease.

  • 13th week: 17. 5. 2024
    Muscle relaxants. Spasmolytics.

  • 14th week: 24. 5. 2024
    Pharmacology of GIT


    SEMINARS spring 2022: Pharmacology I
    Tuesday 7:45 – 10:15, 10:30 – 13:00
    Thursday 7:30 – 10:00

  • 1st week: 20., 22. 2. 2024
    Introduction into the pharmacology

  • 2nd week: 27., 29. 2. 2024
    Preclinical and clinical drug testing

  • 3rd week: 5., 7. 3. 2024
    Mechanisms of transmembrane transport of drugs, transport of drugs across organ barriers. Routes of drug administration.

  • 4th week: 12., 14. 3. 2024
    Pharmacokinetic parameters and their clinical significance

  • 5th week: 19., 21. 3. 2024
    Farmakodynamics

  • 6th week: 26., 28. 3. 2024
    Pharmacology of vegetative nervous system

  • 7th week: 2., 4. 4. 2024
    Drugs affecting the urogenital system (Urinary incontinence, benign prostatic hyperplasia, erectile dysfunction)

  • 8th week: 9., 11. 4. 2024
    Drugs used in ophthalmology

  • 9th week: 16., 18. 4. 2024
    Drugs used in dermatology

  • 10th week: 23., 25. 4. 2024
    1st control TEST

    NSAIDs. Antirheumatics. Antiuratics.

  • 11th week: 30. 4., 2. 5. 2024
    Analgesics-antipyretics. Opioid analgesics.

  • 12th week: 7., 9. 5. 2024
    Substances affecting the central nervous system

  • 13th week: 14., 16. 5. 2024
    General and local anesthetics

  • 14th week: 21., 23. 5. 2024
    2nd control TEST
Literature
    required literature
  • Švihovec Jan a kolektiv. Farmakologie. Grada, Praha, 2018. ISBN 978-80-247-5558-8. URL info
  • RITTER, James, R. J. FLOWER, Graeme HENDERSON, Yoon Kong LOKE, David J. MACEWAN, Emma S. J. ROBINSON and James FULLERTON. Rang & Dale's pharmacology / James M. Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEvan, Emma Robinson, James Fullerton. Tenth edition. London: Elsevier, 2024, xvii, 850. ISBN 9780323873963. info
  • Lüllmann H., Mohr K., Hein L. Barevný atlas farmakologie. Grada, Praha, 2012. ISBN 978-80-247-3908-3. URL info
  • Martínková Jiřina a kolektiv. Farmakologie pro studenty zdravotnických oborů. Grada, Praha, 2018. ISBN 978-80-247-4157-4. URL info
    recommended literature
  • Whalen K. Lippincott Illustrated Reviews: Pharmacology, 7th edition. Lippincott Williams & Wilkins, USA, 2018. ISBN 978-1496384133. info
  • Trevor A, Katzung B, Masters S., Knuidering-Hall M. Katzung & Trevor's Pharmacology Examination and Board Review. McGraw-Hill Medical, 2012. ISBN 0071789235. info
  • Katzung BG. Basic and Clinical Pharmacology. McGraw-Hill Medical, 2011. ISBN 978-0071764018. info
  • Lincová Dagmar, Farghali, Hassan a kol. Základní a aplikovaná farmakologie. Galén, Praha, 2007. ISBN 9788072623730. info
  • Květina J. a kol. Farmakologie pro farmaceuty 2. díl. VFU Brno, 2003. info
  • Květina J. aa kol. Farmakologie pro farmaceuty 3. díl. VFU Brno, 2000. info
  • Květina J. a kol. Farmakologie pro farmaceuty 1. díl. VFU Brno, 1999. info
Teaching methods
lectures, seminars
Assessment methods
The criterion for passing the course is to obtain a credit. The condition for obtaining the credit is the fulfillment of attendance at seminars according to the rules below, which are also saved in the Study Materials of the course in the section Organizational Instructions, and successful completion of both two tests during semester. Test questions will be prepared from the topics that are specified in the course syllabus. The tests will include questions with a choice of more correct answers from the options offered. The student get 1 point for a completely correctly answered question. No points will be deducted for an unfilled or incorrectly answered question. The condition for passing the test is to achieve at least 55% of the maximum possible number of points. In case of unsuccessful completion of any of the tests, it will be possible to repeat it, no more than twice in the term announced in the examination period of the same semester (according to the MU Study and Examination Regulations, Article 18). Completion of the credit from the subject Pharmacology I is one of the conditions for taking the exam from the subject Pharmacology II.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2025.
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