PřF:C9909 Fine process chemistry - Informace o předmětu
C9909 Elements of fine process chemistry
Přírodovědecká fakultajaro 2025
- Rozsah
- 2/0/0. 2 kr. (plus ukončení). Ukončení: zk.
- Vyučující
- RNDr. Petr Beňovský, Ph.D. (přednášející)
- Garance
- doc. RNDr. Ctibor Mazal, CSc.
Ústav chemie – Chemická sekce – Přírodovědecká fakulta - Předpoklady
- Basic knowledge of organic chemistry, organic synthesis, physical chemistry
- Omezení zápisu do předmětu
- Předmět je otevřen studentům libovolného oboru.
- Cíle předmětu
- This lecture should provide much broader information about practical aspects of process chemistry that is very important in the real professional life in process chemistry companies.
- Výstupy z učení
- After successful completion of the lecture (passing the exam) a student should be able to understand factors that apply on different scales of a chemical process. A student should be able to independently decide which reaction system is suitable for a purpose, should be able to distinguish among several options and select the best one. A student is trained to apply theoretical knowledge and understand its impact to the outcome of the chemical reaction.
- Osnova
- Outline of the class; History of fine process chemistry, recent trends, future; Differences between laboratory and larger scale experiments; Scale-up/downscale considerations; Safety; Crystallization (solubility, metastable zone, nucleation, crystal growth, optical resolution, Viedma ripening, attrition enhanced deracemization, seeding, Ostwald ripening, new trends in crystallization); Polymorphism; Typical process operations (mixing, heat transfer, agglomeration, product isolation, distillation, drying, purification, work up, reactors); Continuous manufacturing, flow chemistry; Synthetic route selection; Analytical methods, Process Analytical Technology (PAT), Design of Experiments (DoE), Quality by Design (QbD); Environmental Aspects; Economy, Cost of Goods (CoG); Regulatory issues, patents. Copious example from recent literature about various topics within the whole lecture.
- Literatura
- Neal Anderson, Practical Process Research & Development, Elsevier, 2nd Ed. 2012
- Výukové metody
- Lectures
- Metody hodnocení
- Final written test
- Vyučovací jazyk
- Angličtina
- Další komentáře
- Předmět je vyučován jednou za dva roky.
- Statistika zápisu (jaro 2025, nejnovější)
- Permalink: https://is.muni.cz/predmet/sci/jaro2025/C9909