PřF:Bi4010 Essential molecular biology - Course Information
Bi4010 Essential molecular biology
Faculty of ScienceSpring 2013
- Extent and Intensity
- 2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
- Teacher(s)
- prof. RNDr. Jan Šmarda, CSc. (lecturer)
- Guaranteed by
- prof. RNDr. Jan Šmarda, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Jan Šmarda, CSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science - Timetable
- Wed 8:00–9:50 B11/306
- Prerequisites
- ! Bi4020 Molecular biology && NOW( Bi4010c Essential molecular biology )
Basic knowledge of general zoology and botany, microbiology, genetics, physiology, organic chemistry and biochemistry. - Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- there are 10 fields of study the course is directly associated with, display
- Course objectives
- This lecture is conceived as an introduction into molecular biology and it provides explanation of basic cell processes on molecular level. Structure of genome, principles of gene expression, internal cell organization and its behaviour in the context of multicellular organisms are the main topics of the lecture. At the end of the course, the student will understand molecular principles driving cellular behaviour on basic level.
- Syllabus
- 1. Structure and function of DNA, chromosomal DNA and its packaging in the chromatin fiber, the global structure of chromosomes, how genomes evolve. 2. DNA replication, repair, recombination, and transpozition. 3. Transpcription, splicing, translation, the RNA world and the origin of life. 4. Control of gene expression, regulatry proteins, genetic switches, principles of dcell differentiation, post-transriptional controls, RNA interference. 5. Internal organization of a cell, intracellular compartments, transport of molecules between cell compartments, intracellular vesicular traffic. 6. Mechanisms of cell communication, principles of cell signalling. 7. Cell cycle, principles of control of cell cycle phases, cell division and growth. 8. Programmed cell death. 9. Molecular basis of cancer. 10. Methods available for analyses of nucleic acids and proteins (study of genomes, transriptomes and proteomes, DNA manipulation, PCR, sequencing, transport of DNA to cells, flow cytometry).
- Literature
- ROSYPAL, Stanislav, Jiří DOŠKAŘ, Roman PANTŮČEK, Jana KAILEROVÁ, Jiřina RELICHOVÁ, Vladislava RŮŽIČKOVÁ, Jan ŠMARDA, Jan ŠMARDA and Jiří ŠTĚPÁN. TERMINOLOGIE MOLEKULÁRNÍ BIOLOGIE. České odborné termíny, definice a anglické ekvivalenty (Terminology of molecular biology). První vydání. Brno: Vydavatel Prof. RNDr. Stanislav Rosypal, DrSc. Vodova 80, 612 00 Brno, 2001, 300 pp. ISBN 80-902562-3-6. URL info
- ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky a : Essential cell biology (Orig.). Ústí nad Labem: Espero Publishing, xxvi, 630,. info
- Teaching methods
- lectures follwed by brief discussions
- Assessment methods
- Written test is required. At least 50% of correct answers is required to pass the exam.
- Language of instruction
- Czech
- Follow-Up Courses
- Further comments (probably available only in Czech)
- The course is taught annually.
General note: Studenti profilující své studium směrem k využití molekulárně biologických metod si mohou namísto předmětu Bi4010 zapsat jednu z dvojic předmětů Bi4020 + Bi4020c nebo Bi4020 + Bi4035, která jim bude uznána jakožto předmětový ekvivalent Bi4010. - Listed among pre-requisites of other courses
- Bi0580 Developmetal Genetics
souhlas || Bi4010 || Bi4020 - Bi0999 Molecular ecology
(Bi1030 && Bi2090 && Bi3060 && Bi4010 && Bi7900 && Bi7150) || souhlas - Bi4010c Essential molecular biology - seminar
!Bi4020c && (NOW(Bi4010) || NOW(Bi4020) || Bi4010 || Bi4020) - Bi4020 Molecular biology
!Bi4010 - Bi4025en Molecular Biology
(!Bi4020) && (!Bi4010) && !NOWANY(Bi4010,Bi4020) - Bi5000 Bioinformatics
Bi4010 || Bi4020 - Bi6270 Cytogenetics and cytogenomics
Bi3060 && Bi4020 || NOW(Bi4020) || Bi4010 - Bi6400 Methods of molecular biology
souhlas || Ex_3065 || Imp_9115 || B3120 || B4030 || B5740 || B6130 || B7940 || B4020 || Bi4010 || Bi4020 - Bi7037 Advanced Molecular Virology
Bi5710 && Bi4020 || Bi2060 && Bi4010
- Bi0580 Developmetal Genetics
- Enrolment Statistics (Spring 2013, recent)
- Permalink: https://is.muni.cz/course/sci/spring2013/Bi4010