PřF:Bi5420 General virology - Course Information
Bi5420 General virology
Faculty of ScienceSpring 2016
- Extent and Intensity
- 2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
- Teacher(s)
- prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)
- Guaranteed by
- prof. RNDr. Jan Šmarda, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Ivo Rudolf, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science - Timetable
- Thu 12:00–13:50 B11/235
- Prerequisites
- ( Bi4020 Molecular biology || NOW( Bi4020 Molecular biology )) && ( Bi4090 General microbiology || NOW( Bi4090 General microbiology ))
Course has been established for students of orientation Biology (special biology, molecular biology and genetics) and also to other potential participants interested in virology. - Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- Molecular Biology and Genetics (programme PřF, B-EXB)
- Special Biology (programme PřF, B-EXB)
- Special Biology (programme PřF, B-EXB, specialization Mikrobiology a Molecular Biotechnology)
- Course objectives
- At the end of the course, participant should repeat, translate and apply general terms operating in virology, describe basic structure of viruses, define and translate strategy of replication of viral genome and interpret current taxonomy of viruses. Participant of the course should also characterize important viral diseases of plants, invertebrates and vertebrates including humans and interpret state of the art methods and diagnostic tools used in virology. Participant will employ acquired skills in basic and applied research in virology or in diagnostic laboratories.
- Syllabus
- Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication of viral genome - on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases (definition of terms: disease, virulence, viraemia, persistent and latent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive approach); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis - handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important agents; prions and prion ´s diseases.
- Literature
- recommended literature
- King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
- COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
- HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info
- not specified
- CARTER, John B. and Venetia A. SAUNDERS. Virology : principles and applications. 2nd ed. Chichester: Wiley, 2013, xxix, 364. ISBN 9781119991434. info
- NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
- MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
- FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
- RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
- ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info
- Teaching methods
- Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection. Students are continuously informed with "News in the field of Virology".
- Assessment methods
- Final evaluation is based on written test (Success rate 60%).
- Language of instruction
- Czech
- Follow-Up Courses
- Further comments (probably available only in Czech)
- Study Materials
The course is taught annually. - Listed among pre-requisites of other courses
- Bi7035 Special Virological Techniques
Bi5420 - Bi7035c Special Virological Techniques - practical course
Bi5420 && NOW(Bi7035) - Bi7036 Genetics and Taxonomy of Viruses
Bi4020 && Bi5420 - Bi7038 Ecoepidemiology of Viruses
Bi5420 - Bi7043 Veterinary Virology
Bi5420 - Bi7044 Food and Environmental Virology
Bi5420 - Bi7055 Principles of Antiviral Therapy
Bi5420 && Bi4020 && Bi4090 && Bi5220 - Bi7056 Development and production of vaccines and antivirals
Bi5420 && Bi4020 && Bi4090 && Bi5220
- Bi7035 Special Virological Techniques
- Enrolment Statistics (Spring 2016, recent)
- Permalink: https://is.muni.cz/course/sci/spring2016/Bi5420