LF:aVLFA0721c Pharmacology I - practice

aVLFA0721c Pharmacology I - practice

Faculty of Medicine
autumn 2024

Extent and Intensity

0/3/0. 2 credit(s). Type of Completion: z (credit).
In-person direct teaching

Teacher(s)

Guaranteed by

doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: doc. Mgr. MVDr. Leoš Landa, Ph.D.
Supplier department: Department of Pharmacology – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

aVLFA0721c/30: Tue 24. 9. 16:00–18:30 A16/308, Tue 1. 10. 16:00–18:30 A16/308, Tue 8. 10. 16:00–18:30 A16/308, Tue 15. 10. 16:00–18:30 A16/308, Tue 22. 10. 16:00–18:30 A16/308, Tue 29. 10. 16:00–18:30 A16/308, Tue 5. 11. 16:00–18:30 A16/308, Tue 12. 11. 16:00–18:30 A16/308, Tue 19. 11. 16:00–18:30 A16/308, Tue 26. 11. 16:00–18:30 A16/308, Tue 3. 12. 16:00–18:30 A16/308, Tue 10. 12. 16:00–18:30 A16/308, Tue 17. 12. 16:00–18:30 A16/308, Tue 7. 1. 16:00–18:30 A16/308, Tue 14. 1. 16:00–18:30 A16/308, J. Juřica
aVLFA0721c/31: Tue 24. 9. 16:00–18:30 A19/326, Tue 1. 10. 16:00–18:30 A19/326, Tue 8. 10. 16:00–18:30 A19/326, Tue 15. 10. 16:00–18:30 A19/326, Tue 22. 10. 16:00–18:30 A19/326, Tue 29. 10. 16:00–18:30 A19/326, Tue 5. 11. 16:00–18:30 A19/326, Tue 12. 11. 16:00–18:30 A19/326, Tue 19. 11. 16:00–18:30 A19/326, Tue 26. 11. 16:00–18:30 A19/326, Tue 3. 12. 16:00–18:30 A19/326, Tue 10. 12. 16:00–18:30 A19/326, Tue 17. 12. 16:00–18:30 A19/326, Tue 7. 1. 16:00–18:30 A19/326, Tue 14. 1. 16:00–18:30 A19/326, J. Pistovčáková
aVLFA0721c/32: Thu 26. 9. 13:30–16:00 A16/217, Thu 3. 10. 13:30–16:00 A16/217, Thu 10. 10. 13:30–16:00 A16/217, Thu 17. 10. 13:30–16:00 A16/217, Thu 24. 10. 13:30–16:00 A16/217, Thu 31. 10. 13:30–16:00 A16/217, Thu 7. 11. 13:30–16:00 A16/217, Thu 14. 11. 13:30–16:00 A16/217, Thu 21. 11. 13:30–16:00 A16/217, Thu 28. 11. 13:30–16:00 A16/217, Thu 5. 12. 13:30–16:00 A16/217, Thu 12. 12. 13:30–16:00 A16/217, Thu 19. 12. 13:30–16:00 A16/217, Thu 9. 1. 13:30–16:00 A16/217, Thu 16. 1. 13:30–16:00 A16/217, J. Rudá
aVLFA0721c/33: Mon 23. 9. 16:00–18:30 A19/326, Mon 30. 9. 16:00–18:30 A19/326, Mon 7. 10. 16:00–18:30 A19/326, Mon 14. 10. 16:00–18:30 A19/326, Mon 21. 10. 16:00–18:30 A19/326, Mon 4. 11. 16:00–18:30 A19/326, Mon 11. 11. 16:00–18:30 A19/326, Mon 18. 11. 16:00–18:30 A19/326, Mon 25. 11. 16:00–18:30 A19/326, Mon 2. 12. 16:00–18:30 A19/326, Mon 9. 12. 16:00–18:30 A19/326, Mon 16. 12. 16:00–18:30 A19/326, Mon 6. 1. 16:00–18:30 A19/326, Mon 13. 1. 16:00–18:30 A19/326, L. Landa
aVLFA0721c/34: Mon 23. 9. 16:00–18:30 A16/308, Mon 30. 9. 16:00–18:30 A16/308, Mon 7. 10. 16:00–18:30 A16/308, Mon 14. 10. 16:00–18:30 A16/308, Mon 21. 10. 16:00–18:30 A16/308, Fri 1. 11. 13:30–16:00 A19/118, Mon 4. 11. 16:00–18:30 A16/308, Mon 11. 11. 16:00–18:30 A16/308, Mon 18. 11. 16:00–18:30 A16/308, Mon 25. 11. 16:00–18:30 A16/308, Mon 2. 12. 16:00–18:30 A16/308, Mon 9. 12. 16:00–18:30 A16/308, Mon 16. 12. 16:00–18:30 A16/308, Mon 6. 1. 16:00–18:30 A16/308, Mon 13. 1. 16:00–18:30 A16/308, O. Zendulka

Prerequisites (in Czech)

aVLPF0622p Pathophysiology II - lecture && aVLPA0622c Pathology II - practice

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

General Medicine (programme LF, M-GM)
General Medicine (eng.) (programme LF, M-VL)

Course objectives

The aims of the course are:
to recognize the basic pharmacological terminology and legislation related to the use of drugs and thei prescription
to understand to differences between single drug dosage forms
to understand to the prescription of drugs
to understand to the basics of pharmacokinetics
to understand to the basic facts about the discussed drugs

Learning outcomes

At the end of the course the student knows:
single pharmacoterapeutical drug classes
single drug dosage forms
the modes of action, adverse reactions and basic indications of single drugs of discussed drugs
how to prescribe selected medical preparation or a drug in particular drug dosage form

Syllabus

aVLFA0721c - Pharmacology I - practical lessons

General medicine

Autumn semester 2024
23. 9. – 27. 9. 2024
Topic 1: INFORMATION ON DRUGS
Organisation of practical courses and lectures, our system of evaluation. Repetition of basic pharmacologic terminology. Sub-branches of pharmacology. Sources of information concerning drugs and recommended textbooks. Work with relevant databases (Brevíř, SÚKL, EMA, AISLP), and ATC classification.
30. 9. – 4. 10. 2024
Topic 2: ROUTES OF DRUG ADMINISTRATION, DRUG DOSAGE FORMS
Brief characteristics of the individual drug dosage forms. Clinical significance of the way of drug administration. Overview of the drug dosage forms.
7. 10. – 11. 10. 2024
Topic 3: PRESCRIPTION OF MEDICINAL PRODUCTS
General rules of drug prescription. Prescription of the ready-made preparations.
14. 10. – 18.10. 2024
Topic 4: PHARMACOKINETICS I
Pharmacokinetic processes, parameters and calculations.
21. 10. – 25. 10. 2024
Topic 5: PHARMACOKINETICS II
Pharmacokinetic case reports, simulation of plasma concentrations course, dosage optimization and use of software tools, factors affecting course and value of drug´s plasma concentrations.
28. 10. – 1. 11. 2024
Topic 6: PHARMACODYNAMICS
MULTIPLE-CHOICE TEST 1 (Topics 1-5).
Mechanisms of drug effects - classification, examples. Dose-response curves.
4. 11. – 8. 11. 2024
Topic 7: FACTORS AFFECTING DRUG EFFECTS
Pharmacotherapy in childhood, in pregnancy, in breastfeeding women, in the elderly. Beers list, STOPP-START, FORTA, PLLR.
11. 11. – 15. 11. 2024
Topic 8: PHARMACOVIGILANCE, ADVERSE DRUG REACTIONS
PRESCRIPTION TEST
Classification and characteristics of adverse drug effects. Pharmacovigilance in clinical practice, sources of information on drug safety.
18. 11. – 22. 11. 2024
Topic 9: PHARMACOLOGY OF SYMPATHETIC NERVOUS SYSTEM
Receptors of the sympathetic nervous system (alpha, beta) and their subtypes and organ distribution. Classification and basic pharmacological characteristics of drugs influencing the sympathetic nervous system (pharmacodynamics - both direct and indirect mechanisms of drug action, systems of second messengers).
25. 11. – 29. 11. 2024
Topic 10: PHARMACOLOGY OF PARASYMPATHETIC NERVOUS SYSTEM, SPASMOLYTIC DRUGS, MUSCLE RELAXANTS
Drugs affecting the parasympathetic nervous system - classification, basic pharmacological characteristics. Spasmolytic drugs.
2. 12. – 6. 12. 2024
Topic 11: GLUCOCORTICOIDS, DRUGS USED FOR TREATMENT OF HYPO/HYPERTHYROIDISM
MULTIPLE-CHOICE TEST 2 (Topics 6-10).
Repetition of basic pharmacological characteristics of glucocorticoids and drugs used for treatment of thyroid gland diseases.
9. 12. – 13. 12. 2024
Topic 12: ANALGESICS, PHARMACOTHERAPY OF GOUT
Basic pharmacological characteristics of opioid and non-opioid analgesic drugs, antirheumatoid drugs and drugs used in gout.
16. 12. – 20. 12. 2024
Topic 13: H1-ANTIHISTAMINES, THERAPY OF DISEASES WITH BRONCHIAL OBSTRUCTION, THERAPY OF COUGH
H1-antihistamines, drugs used for therapy of diseases with bronchial obstruction, inhalation drug dosage forms. Drugs used for the therapy of cough.
6. 1. – 10. 1. 2025
Topic 14: PHARMACOTHERAPY OF DIABETES MELLITUS
Anti-diabetic drugs - basic pharmacological characteristics. Drugs used in the therapy of specific and acute conditions in diabetology. Combinations of insulins, insulin regimens.
13. 1. – 17. 1. 2024
Topic 15: SEX HORMONES
MULTIPLE-CHOICE TEST 3 (Topics 11-14).
Endocrine therapy, hormone replacement therapy, hormonal contraceptive drugs. Uterotonics and tocolytics. Hormones of HPA axis.

Literature

required literature

Practicals in Pharmacology, 2009, Náhradní obsah: http://portal.med.muni.cz/article-491-practicals-in-pharmacology.html
RITTER, James, R. J. FLOWER, Graeme HENDERSON, Yoon Kong LOKE, David J. MACEWAN, Emma S. J. ROBINSON and James FULLERTON. Rang & Dale's pharmacology / James M. Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEvan, Emma Robinson, James Fullerton. Tenth edition. London: Elsevier, 2024, xvii, 850. ISBN 9780323873963. info

recommended literature

ZENDULKA, Ondřej, Jan JUŘICA, Leoš LANDA, Alena MÁCHALOVÁ, Gabriela DOVRTĚLOVÁ, Hana KOSTKOVÁ, Jana MERHAUTOVÁ and Kristýna NOSKOVÁ. Soubor kazuistik z farmakologie (Library of case reports). Brno: Masarykova univerzita, 2016. Elportál. ISSN 1802-128X. URL URL URL info
WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015, xi, 664. ISBN 9781451191776. info

not specified

Pharmaceutical practice. Edited by Judith A. Rees - Ian Smith - Jennie Watson. 5th ed. Edinburgh: Churchill Livingstone Elsevier, 2014, xvii, 552. ISBN 9780702051432. info
Waller, Derek - Renwick, Andrew G. - Hillier, Keith. Medical pharmacology and therapeutics. 3rd ed. New York : Elsevier Saunders, 2009. ix, 744 p. ISBN 0-7020-2991-2.
Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8
Pharmacology. Edited by Michelle Alexia Clark. 5th ed. Baltimore: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2012, xii, 612. ISBN 9781451113143. info
LÜLLMANN, Heinz, Lutz HEIN and Klaus MOHR. Color atlas of pharmacology. Translated by Detlef Bierger, Illustrated by Jürgen Wirth. 4th ed. Stuttgart: Thieme, 2011, x, 393. ISBN 9783137817048. info

Bookmarks

https://is.muni.cz/ln/tag/LF:aVLFA0721c!

Teaching methods

Classes take place periodically in the afternoon. The lectures are followed by practical exercises with discussion.

The lectures discuss the basic issues of the subject. This knowledge is further deepened via specific practical tasks in exercises.

Materials for self-study and preparation for exercises will be available in the interactive syllabus/study materials for each topic, including references to the relevant chapters in the textbook.

2 absences from practical lessons are possible.

Assessment methods

3 continuous multiple-choice tests (time limit: 15 min) and 1 prescription test in a paper form. MCQ tests will not be repeated. The prescription test can be repeated only twice.

Each multiple-choice test contains 15 questions. The number of correct answers is given. Student gets 1 point for each completely correct answer, i.e. maximum 15 points for each multiple-choice test; total 45 points for all three MCQ tests.

The prescription test consists of two read-made preparations. For both preparations, the active substance, the drug dosage form and the number of original packages to be prescribed will be listed. The prescription handbook will be available for the test.

To obtain credits, the student has to pass the prescription test successfully and also get at least 6 points from each single multiple-choice test and at least 20 points (minimum) from all three MCQ tests.

Note: Together with the new accreditation of the Pharmacology subject for students of General Medicine, a system of continuous assessment of the student was introduced, when the results achieved in multiple-choice tests in practical lessons and colloquium will be taken into account and included in the final mark from the subject.

Language of instruction

English

Further comments (probably available only in Czech)

The course is taught annually.
Information on the extent and intensity of the course: 45.

The course is also listed under the following terms Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023.

Enrolment Statistics (recent)
Permalink: https://is.muni.cz/course/med/autumn2024/aVLFA0721c

LF:aVLFA0721c Pharmacology I - practice - Course Information

aVLFA0721c Pharmacology I - practice

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