EMHE0221p Histology and Embryology I - lecture

Faculty of Medicine
spring 2025
Extent and Intensity
2/0/0. 1 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
MUDr. Jana Dumková, Ph.D. (lecturer)
doc. MVDr. Aleš Hampl, CSc. (lecturer)
Mgr. Hana Kotasová, Ph.D. (lecturer)
MUDr. Eva Mecová (lecturer)
doc. RNDr. Petr Vaňhara, Ph.D. (lecturer)
MUDr. Ivana Baltasová (seminar tutor)
Guaranteed by
doc. MVDr. Aleš Hampl, CSc.
Department of Histology and Embryology – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Histology and Embryology – Theoretical Departments – Faculty of Medicine
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
"The course consists of two relatively independent disciplines – histology and embryology. By the end of this course, the student will be able to: In the histology part: Understand and explain cell structure, the basic structural principles and functions of connective tissues, the basic characteristics of epithelial tissue, the differences in the structure of various types of muscle tissue, describe the structure and function of nervous tissue, identify individual tissues in histological sections; Describe the microscopic structure of individual human organs and explain the relationships between tissues within organs; Apply the principle of correlation between structure and function at the tissue and organ level; In the embryology part: Describe the development of gametes and explain the principles of meiosis and the regulation of gametogenesis; Accurately describe early embryonic development and explain the development and significance of accessory embryonic structures; Characterize the different stages of embryonic development; Based on the knowledge of the normal course of development of individual organ systems, explain the mechanism of the formation of certain conditions."
Learning outcomes
"By the end of this course, the student will be able to: In the histology part: - Understand and explain cell structure, the basic structural principles and functions of connective tissues, the basic characteristics of epithelial tissue, and the differences in the structure of various types of muscle tissue; - Describe the structure and function of nervous tissue; - Identify individual tissues in histological sections; describe the microscopic structure of individual human organs; - Explain the relationships between tissues within organs; apply the principle of correlation between structure and function at the tissue and organ level; In the embryology part: - Describe the development of gametes and explain the principles of meiosis and the regulation of gametogenesis; - Accurately describe early embryonic development and explain the development and significance of accessory embryonic structures; - Characterize the different stages of embryonic development; - Based on the knowledge of the normal course of development of individual organ systems, explain the mechanism of the formation of certain developmental defects."
Syllabus
  • 1. Introduction. Subject and significance of histology, its classification. Border areas of histology. History, present, and future of the field and the Institute of Histology and Embryology at the Faculty of Medicine, Masaryk University. Cytology: Cell - definition, general structure, compartmentalization. Cell nucleus - ultrastructure and functional significance, chromosomes, nucleolus. 2. Ultrastructure and function of cellular organelles. Cellular inclusions and pigments. Cytoskeleton - microfilaments, intermediate filaments, and microtubules. Modifications of cell surfaces and intercellular junctions. Cell cycle and cell division. Cell differentiation, cell migration, organization of cells into tissues and organs - general aspects. 3. Embryology: Definition of embryology, its significance, and its connection to other medical fields. Human gametes, their structure and development. Meiosis. Regulation of germ cell development. Ovarian and menstrual cycles, their interrelationships. Fertilization. Cleavage. Activation of the embryonic genome. Nuclear transfer. Morula and blastocyst. Embryonic stem cells. 4. Implantation, abnormal implantation sites. Changes in the blastocyst during implantation. Differentiation of the embryoblast and development of extraembryonic structures. Germ disc. Development of the middle germ layer and notochord, differentiation of embryonic mesoderm. Embryo folding. Development of the umbilical cord. Development of the external shape of the embryo. 5. General histology. Definition of tissue, classification of tissues. Connective tissues - characteristics, basic structural components. Connective tissue. 6. Connective tissues: cartilage and bone tissue. Development of bone tissue – ossification. 7. Epithelial tissue - characteristics, classification of epithelia, regeneration. Overview of covering epithelia and glandular epithelium. Characteristics of glandular cells. 8. Nervous tissue - characteristics, development, regeneration. Neurons - structure and function. Synapses. Neuroglia and nerve fiber sheaths. Saltatory conduction of nerve impulses. 9. Muscle tissue - characteristics, development, regeneration. Smooth muscle tissue. Striated skeletal and cardiac muscle tissue. Ultrastructure of myofibrils, mechanism of muscle contraction. Innervation and blood supply of muscles. 10. Morphology of blood elements. Erythrocytes, leukocytes, thrombocytes. White blood cell count. Prenatal and postnatal hematopoiesis. Development of erythrocytes, leukocytes, and thrombocytes. 11. Microscopic anatomy and special embryology. Cardiovascular system. Structure of the heart, conduction system. General structure of the blood vessel wall. Types of capillaries. Angiogenesis. 12. Primitive circulatory system. Development of the heart and blood vessels. Fetal circulation.
Literature
    recommended literature
  • ČECH, Svatopluk, Drahomír HORKÝ and Miroslava SEDLÁČKOVÁ. Přehled embryologie člověka. 4. dotisk 1. vyd. Brno: Masarykova univerzita, 2018, 187 pp. ISBN 978-80-210-5414-1. info
  • ČECH, Svatopluk and Drahomír HORKÝ. Histologie a mikroskopická anatomie pro bakaláře (Histology and microscopical anatomy for bachelors). 1. dotisk 2., přepr. vyd. Brno: Masarykova univerzita, 2017, 138 pp. ISBN 978-80-210-5544-5. info
  • ČECH, Svatopluk and Drahomír HORKÝ. Přehled obecné histologie (An Overview of General Histology). 3. dotisk 2., přeprac. vyd. Brno: Masarykova univerzita, 2017, 127 pp. ISBN 978-80-210-5543-8. info
  • MESCHER, Anthony L. Junqueira's basic histology : text and atlas. Fourteenth edition. New York: McGrawHill Education, 2016, xi, 560. ISBN 9781259250989. info
  • LÜLLMANN-RAUCH, Renate. Histologie. Translated by Radomír Čihák. 1. české vyd. Praha: Grada, 2012, xx, 556. ISBN 9788024737294. info
  • SADLER, T. W. Langmanova lékařská embryologie. 1. české vyd. Praha: Grada, 2011, xviii, 414. ISBN 9788024726403. info
  • VACEK, Zdeněk. Embryologie : učebnice pro studenty lékařství a oborů všeobecná sestra a porodní asistentka. 1. vyd. Praha: Grada, 2006, 255 s. ISBN 9788024712673. info
    not specified
  • KAPELLER, Karol and Viera POSPÍŠILOVÁ. Embryológia človeka : učebnica pre lekárske fakulty. 1. vyd. Martin: Osveta, 2001, 370 s. ISBN 8080630720. info
Teaching methods
lecture
Assessment methods
“Students take the exam only after completing the course Histology and Embryology II - Lecture. Information about the exam process and the syllabus of requirements can be found on the institute’s website: http://www.med.muni.cz/histology/education”
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught: every week.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses
The course is also listed under the following terms spring 2021, spring 2022, spring 2023, spring 2024.
  • Enrolment Statistics (spring 2025, recent)
  • Permalink: https://is.muni.cz/course/med/spring2025/EMHE0221p