ZLFA0722p Pharmacology II - lecture

Faculty of Medicine
autumn 2024
Extent and Intensity
1/0/0. 2 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
doc. RNDr. Ladislava Bartošová, Ph.D. (lecturer)
PharmDr. Mária Hricková (lecturer)
MUDr. Alena Máchalová, Ph.D. (lecturer)
Mgr. Barbora Říhová, Ph.D. (lecturer)
doc. PharmDr. Ondřej Zendulka, Ph.D. (lecturer)
Renata Bláblová (assistant)
Mgr. Marta Vyoralová (assistant)
Mgr. Petra Amchová, Ph.D. (alternate examiner)
doc. MUDr. Regina Demlová, Ph.D. (alternate examiner)
PharmDr. Valentína Focková, PhD. (alternate examiner)
doc. PharmDr. Jan Juřica, Ph.D. (alternate examiner)
Mgr. Jana Kubátová, Ph.D. (alternate examiner)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (alternate examiner)
MUDr. Jana Nováková, Ph.D. (alternate examiner)
doc. PharmDr. Jana Rudá, Ph.D. (alternate examiner)
PharmDr. Lenka Součková, Ph.D. (alternate examiner)
Mgr. Martina Vranková (alternate examiner)
Guaranteed by
doc. PharmDr. Ondřej Zendulka, Ph.D.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: doc. PharmDr. Ondřej Zendulka, Ph.D.
Supplier department: Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Timetable
Thu 19. 9. 13:00–14:40 Virtuální místnost, Thu 26. 9. 13:00–14:40 Virtuální místnost, Thu 3. 10. 13:00–14:40 Virtuální místnost, Thu 10. 10. 13:00–14:40 Virtuální místnost, Thu 17. 10. 13:00–14:40 Virtuální místnost, Thu 24. 10. 13:00–14:40 Virtuální místnost, Thu 31. 10. 13:00–14:40 Virtuální místnost, Thu 7. 11. 13:00–14:40 Virtuální místnost
Prerequisites
ZLFA0621c Pharmacology I - pract. && ZLPA0622c Pathology II - practice && ZLPF0622c Pathophys. II - practice && ZLOR0641c Orthodontics I -pract. && ZLPD0631c Periodontology I - practice
The student has completed courses a ZLFA0722c, aZLFA0621c, aZLFA0621p, aZLPA0622c, aZLPF0622c, aZLOR0641c, and aZLPD0631c
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Upon completion of the course, students can choose the formally correct prescription of drugs using the terminology of valid pharmacopoeia and the preparation of dosage forms of individually prepared and ready-made medicinal products. They should understand the principles of "pharmacological thinking" in drug selection, dosage, pharmacokinetic parameter calculations, choice and technique of administration routes. They should be proficient in the basic pharmacological profile of selected drug groups.
Learning outcomes
Upon completion of the course, the student will:
- be familiar with medicinal product databases and be able to search for specific medicinal products
- distinguish between different routes of administration and dosage forms of a drug and their advantages and disadvantages
- be able to prescribe RMP and IPP
- know the basic pharmacokinetic processes and parameters and can determine the type of mechanism of action of specific drugs
- know the basic pharmacological profile of the drug groups discussed - can recognize drug-drug interactions and can evaluate its severity
Syllabus

  • Basics of Pharmacology II – lectures

    Dentistry

    Autumn semester 2024

    records available online

  • 16. 9. 2024
  • 1. ANALGESICS, PHARMACOTHERAPY OF MIGRAINE AND GOUT
  • Content of the lecture: Classification of analgesics. Basic pharmacologic profile of opioid analgesics, nonsteroid antiinflammatory drugs and analgesics-antipyretics. Basic principles of the therapy of pain, co-analgesics. Drugs used in the therapy of migraine and gout.
  • 23. 9. 2024
  • 2. Psychotropic drugs
  • Content of the lecture: Basic pharmacologic profile of antipsychotics, antiparkinsonics, antidepressants, psychostimulants, anxiolytics, hypnosedatives, and anticonvulsants.
  • 30. 9. 2024
  • 3. GENERAL AND LOCAL ANAESTHETICS, MUSCLE RELAXANTS
  • Content of the lecture: Classification and basic pharmacologic profile of general and local anaesthetic and muscle relaxants. Overview of drugs used in premedication and post-anaesthetic care.
  • 7. 10. 20224
  • 4. ANTIINFECTIVES – ANTIBIOTICS, ANTIMYCOTICS AND ANTIVIRAL AGENTS
  • Content of the lecture: Principles of rational antimicrobial therapy, bacterial resistance, basic pharmacological profile of antibiotics, antimycotics and antiviral agents.
  • 14. 10. 2024
  • 5. DRUGS OF ORAL CAVITY
  • Content of the lecture: Summary of the basic principles of the therapy of diseases of the oral cavity. Overview of drug groups.Farmakoterapie vybraných onemocnění dutiny ústní. Phytotherapy in dentistry.
  • 21. 10. 2024
  • 6. DRUGS OF THE CARDIOVASCULAR SYSTEM I
  • Content of the lecture: Drugs targeting RAAS (ACEi, sartans, kirens), diuretics, aldosterone and mineralocorticoid receptor antagonists. Antihypertensives of the first and second choice, combination of antihypertensives, vasodilators (calcium channel bloskers, nitrates and NO donors).
  • 28. 10. 2024
  • 7. DRUGS OF THE CARDIOVASCULAR SYSTEM II
  • Content of the lecture: Inotropics and antiarrhythmics. Basic pharmacological profiles of anticoagulants, antiplatelets, fibrinolytic, antifibrinolytic, and hemostatics.
  • 4. 11. 2024
  • 8. PHARMACOTHERAPY OF THE TUMOUR DISEASE
  • Content of the lecture: Introduction, principles of the cytostatic therapy, overview of the mechanisms of tumour resistance, TDM and genotyping in oncology. Basic pharmacologic profile of cytostatics. Principles of targeted therapy in oncology – monoclonal antibodies, inhibitors of tyrosine kinases, targeted immunotherapy.
Literature
    required literature
  • RITTER, James, R. J. FLOWER, Graeme HENDERSON, Yoon Kong LOKE, David J. MacEWAN, Emma ROBINSON, James FULLERTON. Rang and Dale's pharmacology. Tenth edition. Elsevier, 2023. 850 p. ISBN 9780323873956.
  • Landa Leoš, Jan Juřica, Kristýna Nosková, Ondřej Zendulka: Vybrané kapitoly z obecné farmakologie pro studenty všeobecného a zubního lékařství na LF MU. Multimediální podpora výuky klinických a zdravotnických oborů :: Portál Lékařské fakulty Masarykovy
  • NOVÁKOVÁ, Jana, Barbora ONDRÁČKOVÁ and Alexandra ŠULCOVÁ. Základy receptury léčivých přípravků pro praktická cvičení z farmakologie - obor Zubní lékařství. Brno: Multimediální podpora výuky klinických a zdravotnických oborů: Portál Lékařské fakulty Masarykovy univerzity, 2010, 96 pp. ISSN 1801-6103. URL info
    recommended literature
  • Essentials of Pharmacology and Therapeutics for Dentistry, 1st Edition, 2024, Frank J. Dowd and Angelo Mariotti
    not specified
  • Farmakologie pro studenty bakalářských oborů na LF MU, Máchalová a kol., 2015, http://portal.med.muni.cz/clanek-644-farmakologie-pro-studenty-bakalarskych-oboru-na-lf-mu.html
  • http://search.ebscohost.com/login.aspx?direct=true&db=nlebk&AN=1160493&lang=cs&site=ehost-live
  • ŠVIHOVEC, Jan a kol. Farmakologie, Praha: Grada, 2018. ISBN 978-80-247-5558-8. www.grada.cz/farmakologie-(1)-8687
  • MARTÍNKOVÁ, Jiřina. Farmakologie pro studenty zdravotnických oborů. 2., zcela přeprac. a doplň. Praha: Grada, 2014. ISBN 9788024713564. info
Teaching methods
In the practicals, the topics discussed are practised as group and individual activities supplemented by the teacher's explanations and discussions. An essential part of the teaching is the students' home preparation for individual lessons and self-study. Students can check their readiness for the lesson by taking the ROPOT before each class. Study materials are available in the form of interactive syllabi.
Assessment methods
The final exam consists of written and oral part.
The final evaluation of the course also contains results of the tests from practicals of both semesters and results of the colloquium test.
The final mark is calculated by the following method:
The relative weight of the mark from tests: 30 %
The relative weight of the mark from the oral exam: 70 %

Written part of the final exam is represented by the ROPOT test that consists of 30 questions (3 points each) undertaken on the day of the final exam. The minimum to pass the test is at least 54 points. If the student fails in the ROPOT, the final exam classification is F. The test can be repeated twice. If students fail in all three attempts in the ROPOT, they can ask the guarantee of the course for a commission oral examination, and the minimal score from the test is used to calculate the final mark.
The ROPOT test has not to be repeated once the student passes it, and in repeated oral examination, the exam starts with the oral part.
In the oral part, the student draws one question of each of three examination question sets and answers the additional questions of the examiner. The relative weights of each examination dataset are as follows: General pharmacology: 25 %; Special pharmacology: 25 %; Selected chapters from special pharmacology: 30 %; Additional questions given by examiner: 20 %. In case a student fails in one of the partial questions, the final mark will be F also.


The mark for the tests is given as follows:
A = 181-210 points
B = 161-180 points
C = 141-160 points
D = 126-140 points
E = 110-125 points
F = less than 110 points
Náhradní absolvování
The course is available online. The credits will be given after final examination.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 15.
Listed among pre-requisites of other courses

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Teacher's information
The lectures of the course ZLFA0722p are in the form of records inserted into the interactive syllabi of the course ZLFA0722c; questions, comments, and consultations can be given during the following seminars or by email directly to the author of the record. The list of exam questions can be found in the Study materials of this course and are also uploaded to the Interactive syllabi of course ZLFA0722c.
The course is also listed under the following terms Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023.
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