LF:VLKB091 Clinical chemistry - Course Information

VLKB091 Clinical chemistry

Extent and Intensity

0/2/0. 1 credit(s). Type of Completion: k (colloquium).

Teacher(s)

doc. MUDr. Milan Dastych, CSc., MBA (lecturer)
MUDr. Michaela Králíková, Ph.D. (lecturer)
prof. MUDr. Vladimír Palyza, CSc. (lecturer)
doc. MUDr. Jaromír Sláma, CSc. (lecturer)
prof. MUDr. Vladimír Soška, CSc. (lecturer)
Mgr. Jiří Slanina, Ph.D. (assistant)

Guaranteed by

prof. MUDr. Vladimír Palyza, CSc.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Contact Person: Lenka Nerudová

Timetable

Mon 1. 10. to Mon 3. 12. Mon 14:45–17:25 206

Prerequisites (in Czech)

( VLFA0822p Pharmacology II - L || VLFA0722p Pharmacology - L ) && VLVL7X61c Internal medicine part 1

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• General Medicine (eng.) (programme LF, M-VL)
• General Medicine (programme LF, M-VL)

Syllabus

• Analytical sources of variation, accuracy and precision. Diagnostic accuracy, sensitivity, specificity, and efficiency of diagnostic tests. Reference ranges, decision values. Collection and processing of specimens, special requirements, general safety rules.
• Assessment and monitoring of nutritional status. Blood plasma proteins. Acute-phase reactants. Principles of nutritional support, enteral and parenteral nutrition. Dietary constituents providing a sufficient energy intake.
• Energy output, nitrogen balance. Indications for nutritional support. Oxygen, transport and metabolism, tissue hypoxia.
• Disorders of lipid and lipoprotein metabolism.
• Ischemic heart disease, congestive cardiac failure. Potassium and magnesium homeostasis.
• Iron and essential microelements metabolism.
• Disturbances of water and sodium balance. Plasma and urine osmolality. Plasma electrolytes in acid-base disorders.
• Assessment of acid-base balance. Investigating an acid-base status, indications for blood acid-base and oxygen measurements, interpretation of results.
• Laboratory evaluation of kidney function. Biochemical monitoring of acute and chronic renal failure, and of patients receiving haemodialysis. Urine sediment.
• Investigation of liver and biliary tract diseases. Signs of the liver injury, differentiating of hyperbilirubinaemias, syndrome of biliary obstruction.
• Clinical biochemistry of the GIT. Gastric acid secretion, maldigestion and malabsorption, assessment of pancreatic function.
• Disorders of saccharide metabolism, diabetes mellitus.
• Calcium and phosphate metabolism. Biochemical markers of bone metabolism (in the assessment of osteoporosis).
• Uric acid, hyperuricaemia. Renal tract stones.
• Laboratory assessment of thyroid and adrenal functions.
• Tumour markers. Biological causes of variation of test results, effects of drugs on chemical tests.

Literature

• RACEK, Jaroslav. Klinická biochemie (Clinical chemistry). 1st ed. Praha: Galén, 1999, 316 pp. ISBN 80-7262-023-1. info
• SCHNEIDERKA, Petr. Vybrané kapitoly z klinické biochemie (Selected Chapters from Clinical Chemistry). 1st ed. Praha: Karolinum, 1998, 120 pp. ISBN 80-7184-505-1. info
• MASOPUST, Jaroslav. Klinická biochemie. Požadování a hodnocení biochemických vyšetření. (Clinical chemistry.). 1st ed. Praha: Karolinum, 1998, 832 pp. část I. a část II. ISBN 80-7184-649-3. info
• LAKER, M.F. Clinical Biochemistry for Medical Students. 1st ed. London: Saunders Co. Ltd., 1996, 357 pp. ISBN 0-7020-1690-X. info
• WHITBY, L.G., A.F. SMITH, G.J. BECKETT and S.W. WALKER. Lecture Notes on Clinical Biochemistry. 5th ed. Oxford: Blackwell Scientific Publications, 1993, 438 pp. ISBN 0-632-03687-7. info

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.
Information on course enrolment limitations: kromě studentů LF maximálně 3 studenti MU v jednom běhu

Listed among pre-requisites of other courses

• VLCH11Xpp Surgery - Pre-graduation Practice
  VLSP03X && VLPD1033c && (VLPG9X1 || VLPG1022p) && VLAM9X1p && VLNE9X1p && (VLON9X1p || VLON091) && VLPY9X1p && VLCH9X33c && (VLIN9X22p || VLIN9X22) && VLVL101 && VLOZ1044 && VLAM9X1p && VLPX102t && VLAJ0222 && (VLLT0222 || VLLT0222s) && VLTZ0754 && vycet(3, VLADV071, VLAF091, VLAL081, VLIA081, VLKB091, VLKF091, VLNO071, VLPM071, VLPM081, VLRL081, VLTL081, VLAT081) && VLCH0731p && VLDI7X1p && VLDV7X1p && VLFA07212p && VLKG7X1p && VLOR7X1c && VLPD7X31p && VLSD7X1p && VLCH0832p && VLFA08222p && VLOL7X1 && VLOT7X1p && VLPX084t && VLST7X1p && VLVL7X61 && VLAM9X1p && VLCH091 && VLDD91CH && VLIN9X22p && VLNE9X1p && VLON9X1p && VLOZ0943p && VLPD0932p && VLPG9X1 && VLPY9X1p && VLDD101I && VLOZ1044 && VLPD1033c && VLPX102t && VLSP03X && VLVL101 && VLVL9X62 && VLVL9X63c && VLVL9X64c && VLVL9X65c  
• VLCH11XX Surgery - State Exam
  VLSP03X && VLPD1033c && (VLPG9X1 || VLPG1022p) && VLAM9X1p && VLNE9X1p && (VLON9X1p || VLON091) && VLPY9X1p && VLCH9X33c && (VLIN9X22p || VLIN9X22) && VLVL101 && VLOZ1044 && VLAM9X1p && VLPX102t && VLAJ0222 && (VLLT0222 || VLLT0222s) && VLTZ0754 && vycet(3, VLADV071, VLAF091, VLAL081, VLIA081, VLKB091, VLKF091, VLNO071, VLPM071, VLPM081, VLRL081, VLTL081, VLAT081) && VLCH0731p && VLDI7X1p && VLDV7X1p && VLFA07212p && VLKG7X1p && VLOR7X1c && VLPD7X31p && VLSD7X1p && VLCH0832p && VLFA08222p && VLOL7X1 && VLOT7X1p && VLPX084t && VLST7X1p && VLVL7X61 && VLAM9X1p && VLCH091 && VLDD91CH && VLIN9X22p && VLNE9X1p && VLON9X1p && VLOZ0943p && VLPD0932p && VLPG9X1 && VLPY9X1p && VLDD101I && VLOZ1044 && VLPD1033c && VLPX102t && VLSP03X && VLVL101 && VLVL9X62 && VLVL9X63c && VLVL9X64c && VLVL9X65c  
• VLPD11Xpp Paediatrics - Pre-graduation Practice
  VLSP03X && VLPD1033c && (VLPG9X1 || VLPG1022p) && VLAM9X1p && VLNE9X1p && (VLON9X1p || VLON091) && VLPY9X1p && VLCH9X33c && (VLIN9X22p || VLIN9X22) && VLVL101 && VLOZ1044 && VLAM9X1p && VLPX102t && VLAJ0222 && (VLLT0222 || VLLT0222s) && VLTZ0754 && vycet(3, VLADV071, VLAF091, VLAL081, VLIA081, VLKB091, VLKF091, VLNO071, VLPM071, VLPM081, VLRL081, VLTL081, VLAT081) && VLCH0731p && VLDI7X1p && VLDV7X1p && VLFA07212p && VLKG7X1p && VLOR7X1c && VLPD7X31p && VLSD7X1p && VLCH0832p && VLFA08222p && VLOL7X1 && VLOT7X1p && VLPX084t && VLST7X1p && VLVL7X61 && VLAM9X1p && VLCH091 && VLDD91CH && VLIN9X22p && VLNE9X1p && VLON9X1p && VLOZ0943p && VLPD0932p && VLPG9X1 && VLPY9X1p && VLDD101I && VLOZ1044 && VLPD1033c && VLPX102t && VLSP03X && VLVL101 && VLVL9X62 && VLVL9X63c && VLVL9X64c && VLVL9X65c && VLCH0731p && VLDI7X1p && VLDV7X1p && VLFA07212p && VLKG7X1p && VLOR7X1c && VLPD7X31p && VLSD7X1p && VLCH0832p && VLFA08222p && VLOL7X1 && VLOT7X1p && VLPX084t && VLST7X1p && VLVL7X61 && VLAM9X1p && VLCH091 && VLDD91CH && VLIN9X22p && VLNE9X1p && VLON9X1p && VLOZ0943p && VLPD0932p && VLPG9X1 && VLPY9X1p && VLDD101I && VLOZ1044 && VLPD1033c && VLPX102t && VLSP03X && VLVL101 && VLVL9X62 && VLVL9X63c && VLVL9X64c && VLVL9X65c  
• VLPD11XX Paediatrics - State Exam
  VLSP03X && VLPD1033c && (VLPG9X1 || VLPG1022p) && VLAM9X1p && VLNE9X1p && (VLON9X1p || VLON091) && VLPY9X1p && VLCH9X33c && (VLIN9X22p || VLIN9X22) && VLVL101 && VLOZ1044 && VLAM9X1p && VLPX102t && VLAJ0222 && (VLLT0222 || VLLT0222s) && VLTZ0754 && vycet(3, VLADV071, VLAF091, VLAL081, VLIA081, VLKB091, VLKF091, VLNO071, VLPM071, VLPM081, VLRL081, VLTL081, VLAT081) && VLCH0731p && VLDI7X1p && VLDV7X1p && VLFA07212p && VLKG7X1p && VLOR7X1c && VLPD7X31p && VLSD7X1p && VLCH0832p && VLFA08222p && VLOL7X1 && VLOT7X1p && VLPX084t && VLST7X1p && VLVL7X61 && VLAM9X1p && VLCH091 && VLDD91CH && VLIN9X22p && VLNE9X1p && VLON9X1p && VLOZ0943p && VLPD0932p && VLPG9X1 && VLPY9X1p && VLDD101I && VLOZ1044 && VLPD1033c && VLPX102t && VLSP03X && VLVL101 && VLVL9X62 && VLVL9X63c && VLVL9X64c && VLVL9X65c  
• VLPG11XX Obstetric and Gynaecology - State Exam
  VLSP03X && VLPD1033c && (VLPG9X1 || VLPG1022p) && VLAM9X1p && VLNE9X1p && (VLON9X1p || VLON091) && VLPY9X1p && VLCH9X33c && (VLIN9X22p || VLIN9X22) && VLVL101 && VLOZ1044 && VLAM9X1p && VLPX102t && VLAJ0222 && (VLLT0222 || VLLT0222s) && VLTZ0754 && vycet(3, VLADV071, VLAF091, VLAL081, VLIA081, VLKB091, VLKF091, VLNO071, VLPM071, VLPM081, VLRL081, VLTL081, VLAT081) && VLDD101I && VLCH0731p && VLDI7X1p && VLDV7X1p && VLFA07212p && VLKG7X1p && VLOR7X1c && VLPD7X31p && VLSD7X1p && VLCH0832p && VLFA08222p && VLOL7X1 && VLOT7X1p && VLPX084t && VLST7X1p && VLVL7X61 && VLAM9X1p && VLCH091 && VLDD91CH && VLIN9X22p && VLNE9X1p && VLON9X1p && VLOZ0943p && VLPD0932p && VLPG9X1 && VLPY9X1p && VLDD101I && VLOZ1044 && VLPD1033c && VLPX102t && VLSP03X && VLVL101 && VLVL9X62 && VLVL9X63c && VLVL9X64c && VLVL9X65c  
• VLPL11Xpp Practical Medicine and Geriatrics
  VLSP03X && VLPD1033c && (VLPG9X1 || VLPG1022p) && VLAM9X1p && VLNE9X1p && (VLON9X1p || VLON091) && VLPY9X1p && VLCH9X33c && (VLIN9X22p || VLIN9X22) && VLVL101 && VLOZ1044 && VLAM9X1p && VLPX102t && VLAJ0222 && (VLLT0222 || VLLT0222s) && VLTZ0754 && vycet(3, VLADV071, VLAF091, VLAL081, VLIA081, VLKB091, VLKF091, VLNO071, VLPM071, VLPM081, VLRL081, VLTL081, VLAT081)  
• VLPL11XX Practical Medicine and Geriatrics
  VLSP03X && VLPD1033c && (VLPG9X1 || VLPG1022p) && VLAM9X1p && VLNE9X1p && (VLON9X1p || VLON091) && VLPY9X1p && VLCH9X33c && (VLIN9X22p || VLIN9X22) && VLVL101 && VLOZ1044 && VLAM9X1p && VLPX102t && VLAJ0222 && (VLLT0222 || VLLT0222s) && VLTZ0754 && vycet(3, VLADV071, VLAF091, VLAL081, VLIA081, VLKB091, VLKF091, VLNO071, VLPM071, VLPM081, VLRL081, VLTL081, VLAT081)  
• VLPP11Xpp Paliative care
  VLSP03X && VLPD1033c && (VLPG9X1 || VLPG1022p) && VLAM9X1p && VLNE9X1p && (VLON9X1p || VLON091) && VLPY9X1p && VLCH9X33c && (VLIN9X22p || VLIN9X22) && VLVL101 && VLOZ1044 && VLAM9X1p && VLPX102t && VLAJ0222 && (VLLT0222 || VLLT0222s) && VLTZ0754 && vycet(3, VLADV071, VLAF091, VLAL081, VLIA081, VLKB091, VLKF091, VLNO071, VLPM071, VLPM081, VLRL081, VLTL081, VLAT081)  
• VLPP11XX Paliative care - seminar
  VLSP03X && VLPD1033c && (VLPG9X1 || VLPG1022p) && VLAM9X1p && VLNE9X1p && (VLON9X1p || VLON091) && VLPY9X1p && VLCH9X33c && (VLIN9X22p || VLIN9X22) && VLVL101 && VLOZ1044 && VLAM9X1p && VLPX102t && VLAJ0222 && (VLLT0222 || VLLT0222s) && VLTZ0754 && vycet(3, VLADV071, VLAF091, VLAL081, VLIA081, VLKB091, VLKF091, VLNO071, VLPM071, VLPM081, VLRL081, VLTL081, VLAT081)  

Zobrazit další předměty

• VLVL11Xpp Internal Medicine - Pre-graduation Practice
  VLSP03X && VLPD1033c && (VLPG9X1 || VLPG1022p) && VLAM9X1p && VLNE9X1p && (VLON9X1p || VLON091) && VLPY9X1p && VLCH9X33c && (VLIN9X22p || VLIN9X22) && VLVL101 && VLOZ1044 && VLAM9X1p && VLPX102t && VLAJ0222 && (VLLT0222 || VLLT0222s) && VLTZ0754 && vycet(3, VLADV071, VLAF091, VLAL081, VLIA081, VLKB091, VLKF091, VLNO071, VLPM071, VLPM081, VLRL081, VLTL081, VLAT081) && VLCH0731p && VLDI7X1p && VLDV7X1p && VLFA07212p && VLKG7X1p && VLOR7X1c && VLPD7X31p && VLSD7X1p && VLCH0832p && VLFA08222p && VLOL7X1 && VLOT7X1p && VLPX084t && VLST7X1p && VLVL7X61 && VLAM9X1p && VLCH091 && VLDD91CH && VLIN9X22p && VLNE9X1p && VLON9X1p && VLOZ0943p && VLPD0932p && VLPG9X1 && VLPY9X1p && VLDD101I && VLOZ1044 && VLPD1033c && VLPX102t && VLSP03X && VLVL101 && VLVL9X62 && VLVL9X63c && VLVL9X64c && VLVL9X65c  
• VLVL11XX Internal Medicine - State Exam
  VLSP03X && VLPD1033c && (VLPG9X1 || VLPG1022p) && VLAM9X1p && VLNE9X1p && (VLON9X1p || VLON091) && VLPY9X1p && VLCH9X33c && (VLIN9X22p || VLIN9X22) && VLVL101 && VLOZ1044 && VLAM9X1p && VLPX102t && VLAJ0222 && (VLLT0222 || VLLT0222s) && VLTZ0754 && vycet(3, VLADV071, VLAF091, VLAL081, VLIA081, VLKB091, VLKF091, VLNO071, VLPM071, VLPM081, VLRL081, VLTL081, VLAT081) && VLCH0731p && VLDI7X1p && VLDV7X1p && VLFA07212p && VLKG7X1p && VLOR7X1c && VLPD7X31p && VLSD7X1p && VLCH0832p && VLFA08222p && VLOL7X1 && VLOT7X1p && VLPX084t && VLST7X1p && VLVL7X61 && VLAM9X1p && VLCH091 && VLDD91CH && VLIN9X22p && VLNE9X1p && VLON9X1p && VLOZ0943p && VLPD0932p && VLPG9X1 && VLPY9X1p && VLDD101I && VLOZ1044 && VLPD1033c && VLPX102t && VLSP03X && VLVL101 && VLVL9X62 && VLVL9X63c && VLVL9X64c && VLVL9X65c  
• VLZP11XX Public Health - State Exam
  VLSP03X && VLPD1033c && (VLPG9X1 || VLPG1022p) && VLAM9X1p && VLNE9X1p && (VLON9X1p || VLON091) && VLPY9X1p && VLCH9X33c && (VLIN9X22p || VLIN9X22) && VLVL101 && VLOZ1044 && VLAM9X1p && VLPX102t && VLAJ0222 && (VLLT0222 || VLLT0222s) && VLTZ0754 && vycet(3, VLADV071, VLAF091, VLAL081, VLIA081, VLKB091, VLKF091, VLNO071, VLPM071, VLPM081, VLRL081, VLTL081, VLAT081) && VLDD101I && VLCH0731p && VLDI7X1p && VLDV7X1p && VLFA07212p && VLKG7X1p && VLOR7X1c && VLPD7X31p && VLSD7X1p && VLCH0832p && VLFA08222p && VLOL7X1 && VLOT7X1p && VLPX084t && VLST7X1p && VLVL7X61 && VLAM9X1p && VLCH091 && VLDD91CH && VLIN9X22p && VLNE9X1p && VLON9X1p && VLOZ0943p && VLPD0932p && VLPG9X1 && VLPY9X1p && VLDD101I && VLOZ1044 && VLPD1033c && VLPX102t && VLSP03X && VLVL101 && VLVL9X62 && VLVL9X63c && VLVL9X64c && VLVL9X65c  

• Enrolment Statistics (Autumn 2007, recent)
  
• Permalink: https://is.muni.cz/course/med/autumn2007/VLKB091