VLIM051p Immunology - lecture

Faculty of Medicine
Autumn 2009
Extent and Intensity
1/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. MUDr. Jiří Litzman, CSc. (lecturer)
prof. MUDr. Jindřich Lokaj, CSc. (lecturer)
Guaranteed by
prof. MUDr. Jiří Litzman, CSc.
Department of Clinical Immunology and Allergology – Institutions shared with St. Anne's Faculty Hospital – Faculty of Medicine
Contact Person: prof. MUDr. Jindřich Lokaj, CSc.
Timetable
Mon 21. 9. to Fri 6. 11. Tue 13:30–15:10 I.CHK N01001
Prerequisites (in Czech)
VSBC0221p Biochemistry I -lect. && ( VSLC011p Med.Chem.- lecture || VSLC021p Medical chemistry -l ) && VSBI0222p Biology II - lecture &&( VSBF011p Biophysics || VLBF011p Biophysics-lect. ) && VSFY0422p Physiology II - lecture && ( VSBC041s Biochemistry II -s || VSBC041c Biochemistry II -pract. ) && ( VSLT0221s Bas. Med. Terminol. II -s || VSLT011s Bas. Med. Terminology -l ) && VSET021 Medical Ethics I
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course covers basic aspects of the structure and function of the immune system in humans. Topics include mechanisms of non- specific immunity with main emphasis on the inflammatory process, such as humoral and cellular branches of the specific immune response. It includes mainly mechanisms of activation of the immune response and its regulation. Special emphasis is given to immune response to microbes and immunoprophylaxis to infectious and non-infectious diseases. After finishing the course the students will understand and be able to explain the mechanisms of the immune response in physiology, such as immune system disturbances leading to immunopathological diseases.
Syllabus
  • Immunology in medicine. Medical subject allergology and clinical immunology. Physiology and pathology of the immune system.
  • Immunological concept of “own”, “foreign”, “dangerous”.
  • Anatomy and cellular elements of the immune system.
  • Innate or natural immunity: phagocytosis, NK cells, cytotoxicity, interferon system, complement system, acute phase reaction, inflammation.
  • B lymphocytes and immunoglobulins.Genetic basis of immunoglobulin heterogeneity.Biological properties of antibodies.
  • T-lymphocytes, their development and effector functions. Polarisation of T-lymphocytes (T1, T2, Th17). Cytotoxicity. Cytokines. Major histocompatibility complex: structure, function.
  • Activation of T and B cells by antigen.Interactions between antigen-presenting cells and T- and B-lymphocytes.
  • Regulation of the immune reaction.
  • Compartmentalization of the immune response. Mucosal immunity.
  • Immunity against infectious agents. Microbial antigens.
  • Active and passive immunisation.
  • Age factor and immune system in humans
Literature
  • HOŘEJŠÍ, Václav and Jiřina BARTŮŇKOVÁ. Základy imunologie. 3. vyd. Praha: Triton, 2005, 279 s. ISBN 8072546864. info
  • BUC, Milan. Imunológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2001, 463 s. ISBN 8022406678. info
  • Abbas, Abul - Lichtman, Andrew. Basic Immunology. Philadelphia, Saunders, 336 s, ISBN: 1416029745
  • Doan, Thao - Melvold, Roger - WEaltenbaugh, Carl. Concise Medical Immunology. Philadelphia: LWW. 2005. 267s. ISBN: 0-7817-7541-X
Teaching methods
The subject is given in a form of lectures
Assessment methods
Subject is finished by an oral exam which is composed of two questions. One of them is from the subject of a theoretical immunology, the second one from the patophysiogy of the immune system. A credit from the subject VLIM051c is required for the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (Autumn 2009, recent)
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