BLMB011p Molecular and Cellular Biology - lecture

Faculty of Medicine
Autumn 2012
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. MUDr. Augustin Svoboda, CSc., dr. h.c. (lecturer)
Mgr. Hana Hříbková, Ph.D. (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. MUDr. Augustin Svoboda, CSc., dr. h.c.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: prof. MUDr. Augustin Svoboda, CSc., dr. h.c.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Tue 25. 9. to Fri 21. 12. Tue 9:20–11:00 B11/114
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The subject will provide a thorough overview of current knowledge in molecular and cell biology: cell structure and function, storage and expression of genetic information, cell division and differentiation, cellular interactions and malignant transformation. Students will gain practical skills in microscopy, in performing biological experiments and their evaluation. The acquired knowledge will help students to understand better other subjects – techniques of molecular genetics, histology, biochemistry, physiology, pathology and human and clinical genetics.
Syllabus
  • Mechanisms of cellular organization of living things. Biopolymers
  • Cell memory
  • Gene expression: Transcription and its control
  • Translation. Metabolism of proteins
  • DNA replication
  • Biomembranes and transformation of energy. Membrane transport
  • Structure of cell nucleus
  • Cytoskeleton. Molecular motors
  • Cell cycle. Mitosis and meiosis
  • Exocytosis and endocytosis – molecular dissection of metabolic pathways
  • Cell signaling. Apoptosis
  • Genetic control of embryogenesis. Cellular differentiation
  • Stem cells and their applications in medicine
  • Tumor cell transformation
Literature
    recommended literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • CAMPBELL, Neil A. Biologie. Edited by Jane B. Reece. Vyd. 1. Brno: Computer Press, 2006, xxxiv, 133. ISBN 8025111784. info
  • NEČAS, Oldřich. Obecná biologie pro lékařské fakulty. 1. vyd. Jinočany: H&H, 2000, 554 s. ISBN 8086022463. info
Teaching methods
two-hour lecture per week
Assessment methods
Written exam of multiple choice type. The test contains 45 questions generated from 15 syllabus units. Evaluation is made electronically, and the results are transferred to IS. Maximal number of points is 45, for successful exam is needed 20 points.
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (Autumn 2012, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2012/BLMB011p