BLMB011p Molecular and Cellular Biology - lecture

Faculty of Medicine
autumn 2018
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
Mgr. Kateřina Straková, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
Jana Růžičková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Straková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Tue 9:00–10:50 B11/114
Prerequisites
Knowledge high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_CZ.qwarp) or similar.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding the chemical composition, structure and properties of the main cellular components
- understanding the basic processes in the cell; and understanding the principles of pathology of these processes in cancer and genetic diseases
- understanding the basic principles of heredity
Learning outcomes
After completing the course the student will be able to:
- describe the composition, structure and functions of prokaryotic and eukaryotic cells
- Explain the principles of intercellular communication and cell differentiation
- Explain the principles of regulation and purpose of cell division (mitosis and meiosis)
- explain basic principles of heredity and nature of human genetic diseases, describe basic methods of gene diagnostics
- Explain the principles of tumour transformation
Syllabus
  • Introduction. Biopolymers I - proteins
  • Biopolymers II - nucleic acids and DNA replication
  • From genes to proteins - expression of genetic information
  • Cell architecture, membrane system in cells
  • The cytoskeleton
  • Cell communication. Cell differentiation. Stem cells.
  • Mitosis and meiosis
  • Cell division and cell cycle control. Apoptosis
  • Principles of heredity I – genes and gene mutations
  • Principles of heredity II – karyotype and chromosomal aberrations
  • Methods of studying the genes. Gene diagnostics
  • Bacteria and viruses
  • Malignant transformation of cells. Cancer
  • substitution lecture
Literature
    recommended literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • PRITCHARD, D. J. and Bruce R. KORF. Základy lékařské genetiky. první české vydání. Praha: Galén, 2007, 182 stran. ISBN 9788072624492. info
Teaching methods
two-hour lecture with discussion per week
Assessment methods
The course is completed with a written examination test with 60 questions (30 multiple choice questions, where negative marking applies for incorrect answers + 30 questions where the student selects from true/false). At least 30 points out of 60 are needed to pass. More information on the exam to be found on https://is.muni.cz/auth/el/1411/podzim2018/BLMB011p/op/Informace_a_pokyny_ke_zkousce.pdf
The exam requires knowledge discussed at the lectures and practices. The exam tests the understanding of the discussed knowledge in context.
Successfull passing of the subject's practice is required for attending the exam.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/1411/podzim2018/BLMB011p/index.qwarp
The course is also listed under the following terms Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (autumn 2018, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2018/BLMB011p