LF:BVTO0311p Med. toxicology -l. - Course Information
BVTO0311p Medical toxicology - lecture
Faculty of MedicineAutumn 2016
- Extent and Intensity
- 1/0/0. 2 credit(s). Type of Completion: zk (examination).
- Teacher(s)
- RNDr. Ondřej Zvěřina, Ph.D. (lecturer)
RNDr. Danuše Lefnerová, Ph.D. (lecturer)
doc. RNDr. Pavel Coufalík, Ph.D. (lecturer) - Guaranteed by
- prof. MUDr. Drahoslava Hrubá, CSc.
Department of Public Health – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Public Health – Theoretical Departments – Faculty of Medicine - Timetable
- Tue 7:30–9:00 A21/107
- Prerequisites
- BVBC0221p Biochemistry I -lect. || VSBC0221p Biochemistry I -lect. && BVEK011p Ecology
Prerequisites: biochemistry - Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- Nutritive therapist (programme LF, B-SZ)
- Course objectives
- On successful completion of the course student will obtain the basic knowledge about the field of general toxicology: routes of exposure (intake of chemicals); internal exposure (uptake of chemicals); metabolism; genetic polymorphism and its role in the individual vulnerability; routes of excretion. Biological effects of exposure to xenobiotics, methods of measurements and evaluation;
In the specific part of medical toxicology, student will be able to understand the role of important xenobiotics contaminated the food chains in the exposure, biological effects and prevention. - Syllabus
- Environmental chemical contaminants - problems, world catastrophes. Intake, uptake in toxicology. Anti-chemical defense systems in the human body. Metabolism of chemicals, the role of microsomal enzymes. Genetic determination of the differences in the metabolism of xenobiotics, the effects on human sussceptibility to chemicals. The methods of experimental studies in toxicology, interpretation of their results for the human exposure. Polychlorinated hydrocarbons: DDT, PCB, PCDD, PCDF: toxicology, control. Heavy metals: Hg, Pb, Cd, As, Cr: toxicology, control. Polycyclic aromatic hydrocarbons and their nitroso-derivates: toxicology, control. Pesticides, natural pesticides.
- Literature
- Ph.S.Guzelian (Ed): Similarities and differences between children and adults. ILSI Press, Washington, 1992. ISBN 0-944398-07-3
- F.C. LU: Basic toxicology. Taylor, Francis (Ed), Washington, 1996. ISBN 1-56032-380-9
- Manuál prevence v lékařské praxi. Edited by Kamil Provazník - Miroslav Cikrt - Lumír Komárek. Vyd. 1. Praha: Státní zdravotní ústav, 2000, 158 s. ISBN 8070711612. info
- KOTULÁN, Jaroslav and Drahoslava HRUBÁ. Preventivní lékařství :učební text pro lékařské fakulty. Brno: Masarykova univerzita, 1993, 207 s. ISBN 80-210-0563-7. info
- KOTULÁN, Jaroslav, Drahoslava HRUBÁ and Vladimír BENCKO. Preventivní lékařství :učební text pro lékařské fakulty. Brno: Masarykova univerzita, 1993, 285 s. ISBN 80-210-0336-7. info
- Teaching methods
- Lectures.
- Assessment methods
- Written tests, oral exam
- Language of instruction
- Czech
- Follow-Up Courses
- Further Comments
- Study Materials
- Listed among pre-requisites of other courses
- Enrolment Statistics (Autumn 2016, recent)
- Permalink: https://is.muni.cz/course/med/autumn2016/BVTO0311p