BVTO0311p Medical toxicology - lecture

Faculty of Medicine
autumn 2021
Extent and Intensity
1/0/0. 2 credit(s). Type of Completion: zk (examination).
Teacher(s)
RNDr. Ondřej Zvěřina, Ph.D. (lecturer)
RNDr. Danuše Lefnerová, Ph.D. (lecturer)
doc. RNDr. Pavel Coufalík, Ph.D. (lecturer)
Ing. Veronika Išová (assistant)
Guaranteed by
RNDr. Ondřej Zvěřina, Ph.D.
Department of Public Health – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Public Health – Theoretical Departments – Faculty of Medicine
Timetable
Tue 14. 9. 11:00–12:40 A21/112, Tue 21. 9. 11:00–12:40 A21/112, Tue 5. 10. 11:00–12:40 A21/112, Tue 12. 10. 11:00–12:40 A21/112, Tue 19. 10. 11:00–12:40 A21/112, Tue 26. 10. 11:00–12:40 A21/112, Tue 2. 11. 11:00–12:40 A21/112, Tue 9. 11. 11:00–12:40 A21/112, Tue 16. 11. 11:00–12:40 A21/112, Tue 23. 11. 11:00–12:40 A21/112, Tue 30. 11. 11:00–12:40 A21/112, Tue 7. 12. 11:00–12:40 A21/112, Tue 14. 12. 11:00–12:40 A21/112
Prerequisites
BVBC0221p Biochemistry - lect. || VSBC0221p Biochemistry I -lect. && BVEK011p Ecology
Prerequisites: biochemistry
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the course is to acquaint students with the basics of general toxicology: pathways of exposure, internal exposure, metabolism; genetic polymorphism affecting susceptibility to chemical exposure. Excretion. Effects of exposure to chemicals, detection methods;
In a special section of medical toxicology, they become acquainted with selected chemical substances contaminating food chains, forms of population exposure, their effects in the organism, and prevention options.
Learning outcomes
At the end of the course student is able to describe the main contaminants in the environment and mechanism of their action on human health.
Syllabus
  • Environmental chemical contaminants - problems, world catastrophes. Intake, uptake in toxicology. Anti-chemical defense systems in the human body. Metabolism of chemicals, the role of microsomal enzymes. Genetic determination of the differences in the metabolism of xenobiotics, the effects on human sussceptibility to chemicals. The methods of experimental studies in toxicology, interpretation of their results for the human exposure. Polychlorinated hydrocarbons: DDT, PCB, PCDD, PCDF: toxicology, control. Heavy metals: Hg, Pb, Cd, As, Cr: toxicology, control. Polycyclic aromatic hydrocarbons and their nitroso-derivates: toxicology, control. Pesticides, natural pesticides.
Literature
    recommended literature
  • LINHART, Igor. Toxikologie : interakce škodlivých látek s živými organismy, jejich mechanismy, projevy a důsledky. 2., upravené a rozšířen. Praha: Vysoká škola chemicko-technologická v Praze, 2014, 410 stran. ISBN 9788070808771. info
  • PROKEŠ, Jaroslav. Základy toxikologie : obecná toxikologie a ekotoxikologie. 1. vyd. Praha: Karolinum, 2005, 248 s. ISBN 802461085X. info
    not specified
  • F.C. LU: Basic toxicology. Taylor, Francis (Ed), Washington, 1996. ISBN 1-56032-380-9
Teaching methods
Lectures.
Assessment methods
Oral exam
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
Information on the extent and intensity of the course: 15.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (autumn 2021, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2021/BVTO0311p