VLBI0121p Biology I - lecture

Faculty of Medicine
Autumn 2016
Extent and Intensity
1/0. 0 credit(s). Type of Completion: z (credit).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
prof. Ing. Petr Dvořák, CSc. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
RNDr. Pavel Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
RNDr. Mário Špírek, PhD. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (lecturer)
Jana Růžičková (assistant)
Mgr. Kateřina Straková, Ph.D. (assistant)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Cetkovská, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Wed 10:30–11:20 B22/116 aula
Prerequisites
Knowledge of high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/anim/overview_CZ.qwarp) or similar, and knowledge of all previous lectures and practical classes of the subject. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; knows basic principles of bacterial and viral diseases; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects, and understands the principle of genetic determination of hereditary diseases; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Syllabus
  • Week 1:
  • Introduction to medical biology - from understanding of cellular principle to modern biomedicine (prof. Ing. Petr Dvořák, CSc.)
  • Week 2:
  • Bacteria and viruses – characteristics, reproduction strategies and principles of treatment (Mgr. Kateřina Vopěnková, Ph.D.)
  • Week 3:
  • Structure, functions and function anomalies of eukaryotic cells (Mgr. Kateřina Cetkovská, Ph.D.)
  • Week 4:
  • Cells in the context of the entire organism – principles of cell adhesion and intercellular communication (Mgr. Kateřina Cetkovská, Ph.D.)
  • Week 5:
  • Cell signalling and the principle of cell differentiation (Mgr. Kateřina Vopěnková, Ph.D.)
  • Week 6:
  • Cell death – mechanisms and regulation of apoptosis and its significance for medicine (doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 7:
  • The importance of genetic information – the journey from a gene to protein; DNA replication (RNDr. Mário Špírek, Ph.D.)
  • Week 8:
  • Cell cycle – molecular mechanisms of regulation and significance for oncology (Mgr. Stjepan Uldrijan, CSc.)
  • Week 9:
  • Mitotic division in normal and cancer cells (Mgr. Vladimír Rotrekl, Ph.D.)
  • Week 10:
  • dissection week - no lecture
  • Week 11:
  • Meiosis and the principle of genetic variability (Mgr. Vladimír Rotrekl, Ph.D.)
  • Week 12:
  • The basics of genetics, the nature of dominance and recessivity (Mgr. Kateřina Vopěnková, Ph.D.)
  • Week 13:
  • Genetics of human diseases – molecular principles of genetically determined diseases (doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 14:
  • Epigenetics – the link between genes and environment (Mgr. Stjepan Uldrijan, CSc.)
  • Week 15:
  • substitution lecture
Literature
    required literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • PRITCHARD, D. J. and Bruce R. KORF. Základy lékařské genetiky. první české vydání. Praha: Galén, 2007, 182 stran. ISBN 9788072624492. info
    recommended literature
  • HARDIN, Jeff, Gregory BERTONI and Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012, xxviii, 79. ISBN 9780321709783. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008, xxxvii, 11. ISBN 9780716776017. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
  • WEINBERG, Robert A. The biology of cancer. Second edition. London: Garland Science, 2013, xx, 876. ISBN 9780815345282. info
  • WOLPERT, L. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002, xxv, 542. ISBN 0198792913. info
    not specified
  • CAMPBELL, Neil A. Biologie. Edited by Jane B. Reece. Vyd. 1. Brno: Computer Press, 2006, xxxiv, 133. ISBN 8025111784. info
Teaching methods
lecture
Assessment methods
Lecture attendance is optional. Students continue with following subjects without proof of this semester's knowledge. Biology I (VLBI0121p) is followed by Biology II (VLBI0222p) that is completed with a written examination test. The test is based on knowledge of all topics from both semesters (lectures, seminars, practices).
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/1411/podzim2016/VLBI0121p/index.qwarp
The course is also listed under the following terms Autumn 2015, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (Autumn 2016, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2016/VLBI0121p