BVLC011p Medical Chemistry-lecture

Faculty of Medicine
autumn 2020
Extent and Intensity
2/0/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. RNDr. Jiří Dostál, CSc. (lecturer)
RNDr. Hana Paulová, CSc. (lecturer)
Mgr. Jiří Slanina, Ph.D. (lecturer)
prof. RNDr. Eva Táborská, CSc. (lecturer)
doc. RNDr. Josef Tomandl, Ph.D. (lecturer)
Mgr. Marie Tomandlová, Ph.D. (lecturer)
MUDr. Michaela Králíková, Ph.D. (assistant)
Guaranteed by
Mgr. Marie Tomandlová, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Timetable
Mon 13:00–14:50 B11/334
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the course is to provide knowledge of chemistry, which is necessary for the understanding of chemical principles applied in other subjects, especially in biochemistry. The student will learn about the properties of the solutions, and general physicochemical laws. The properties of elements and compounds of importance in medicine, nutrition and toxicology are presented. The subject should also provide an overview of the compounds and reactions involved in metabolism and toxicologically relevant organic compounds.
Learning outcomes
Students will be able to understand basics of general, inorganic and organic chemistry to the extent necessary for the further study of biochemistry.
They will be able to apply general physicochemical laws to processes in living organisms.
They will be able to describe the chemical properties of the most important biogenic elements and essential compounds of importance in medicine, nutrition and toxicology. They will be able to describe and discuss the properties and reactions of organic and bioorganic compounds important for the understanding of biochemical processes.
Syllabus
  • Dispersion systems. Coligative properties. Osmotic pressure. Colloid solutions. Surfactants.
  • Electrolytes, activity of ions, ionic strength. Acid-base reactions, pH, hydrolysis of salts, buffers.
  • Chemical thermodynamics, bioenergetics. Chemical kinetics.
  • Redox reactions, redox potentail, relation to Gibbs energy. Biochemially important redox systems. Solubility of salts, precipitacion reactions.
  • Biologically important elements and their compounds.
  • Biological important reactions of organic compounds (alcohols, citrate cycle, transaminations).
  • Biologically important heterocyclic compounds.
  • Structure and properties of monosaccharides, disaccharides.
  • Homopolysaccharides. Heteropolysaccharides.
  • Fatty acids, triacylglycerols, phospholipids, glycolipids.
  • Steroids. Steroid hormones. Calciols. Eicosanoids.
  • Amino acids, polarity, biochemicalké conversions.
  • Proteins, structure. Examples of globular, fibrous, membrane proteins. Glycoproteins, hemoproteins.
  • Nucleosides. Nucleotides. Nucleis acids.
Literature
Teaching methods
Teaching form are lectures. Supplementary subjects are seminars and practicals (BVLC011s and BVLC011c).
Assessment methods
Written examination.
Student must have course-unit credit of seminar and practicals (BVLC011s and BVLC011c) in the day of exam.
Examination from Medical chemistry is only written. The test consists from two parts. The first part is solved on computers in the computer room of Department of Biochemistry: calculations (concentration, pH, buffers, osmotic pressure) – see seminars simple questions (multiple choice or free answer) structural formulas (essential organic and inorganic compounds). The second part is written and is focused on the active knowledge of structural formulas of the most important compounds, expression of important biochemical reactions by chemical equations and the ability to formulate the basic physico-chemical relationships or to draw graphs. For detailed instructions see Study materials - Information about exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
Information on completion of the course: přistoupení ke zkoušce je podmíněno úspěšným ukončením předmětů BVLC011s a BVLC011c.
The course is taught annually.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (autumn 2020, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2020/BVLC011p