FaF:FAFO2_13 Dosage Forms and Biopharmacy - Course Information

FAFO2_13 Dosage Forms and Biopharmacy II

Extent and Intensity

3/6/0. 11 credit(s). Type of Completion: zk (examination).

Teacher(s)

doc. PharmDr. Aleš Franc, Ph.D. (lecturer)
doc. PharmDr. Jan Gajdziok, Ph.D. (lecturer)
doc. PharmDr. Kateřina Kubová, Ph.D. (lecturer)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (lecturer)
PharmDr. Jakub Vysloužil, Ph.D. (lecturer)
doc. PharmDr. Aleš Franc, Ph.D. (seminar tutor)
doc. PharmDr. Jan Gajdziok, Ph.D. (seminar tutor)
doc. PharmDr. Kateřina Kubová, Ph.D. (seminar tutor)
PharmDr. Jakub Vysloužil, Ph.D. (seminar tutor)
PharmDr. Miroslava Pavelková, Ph.D. (seminar tutor)

Guaranteed by

doc. PharmDr. Kateřina Kubová, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy

Timetable

Thu 9:15–11:30 18-122

• Timetable of Seminar Groups:

FAFO2_13/01: Thu 12:30–14:00 18-122, Thu 14:00–17:00 18-138

Prerequisites

Dosage Forms and Biopharmacy I
Students can study this course only after completing the course Dosage Forms and Biopharmacy I

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 12 student(s).
Current registration and enrolment status: enrolled: 0/12, only registered: 0/12

fields of study / plans the course is directly associated with

• Multidisciplinary studies at Faculty of Pharmacy (programme CST, KOS)
• Pharmacy (programme FaF, M-FARMA)

Course objectives

One of the main obligatory pharmaceutical disciplines dealing with preparation, manufacturing and quality control of medicaments including technological procedures, equiment, excipients and appropriate analytical devices. It covers the influence of the application form on drug bioavailability.

Learning outcomes

After completing the course, student will: - theoretically know the classification, requirements, excipients, technological process of preparation and production of solid dosage forms, including their evaluation; - theoretically know the classification, requirements, excipients, technological process of preparation and production of dosage forms with controlled drug release, including their evaluation; - know the basic aspects of dosage forms in relation to the drug bioavailability - practically know the preparation of semisolid and solid dosage forms in pharmacy conditions;

Syllabus

• Topic of lecture
  
  Semisolid dosage forms – ointments
  Semisolid dosage forms - creams, gels, pastes
  Dosage forms for rectal application
  Dosage forms for vaginal application.
  Pharmaceutical incompatibilities in dosage forms.
  Granules, granulation methods. Evaluation of powders and granules.
  Tablets, their production, and evaluation.
  Coated products, their production and evaluation.
  Oral dosage forms with controlled drug release
  Pharmaceutical aerodispersions.
  Validation in pharmaceutical technology
  Regulatory authorities evaluation of dosage forms
  Development of new drugs from galenical perspective
  
  Topic - of practical labs
  
  Semisolid dosage forms - theoretical aspect of preparation
  Ointments, Creams. Pastes, Gels
  Ointments, Creams. Pastes, Gels
  Rectal and vaginal dosage forms - theoretical aspect of preparation
  Preparation of rectal suppositories
  Preparation of vaginal globules
  Incompatibilities in liquid, semisolid and solid dosage forms - theoretical aspect of preparation
  Technological processes in preparation of difficult prescriptions. Alternative training.
  Wet and melt granulations.
  Tablets preparation by direct compression.
  Evaluation of solid dosage forms.
  Credit test
  

Literature

recommended literature
• European Pharmacopoeia 9. info
• The texts which are available during the lectures. info
• Handbook of Pharmaceutical Excipients. Great Britain, 2006. ISBN 1-58212-058-7. info

Teaching methods

1Lectures
2Lab training
3 Homework

Assessment methods

1.Written test
2.Systematic observation of student during lab training
3.Practical test of student skills
3.Oral examination

Language of instruction

English

Further comments (probably available only in Czech)

Study Materials
The course can also be completed outside the examination period.

Teacher's information

Lectures are recommended due to the lack of suitable literature. Students can study this course only after completing the course Dosage Forms and Biopharmacy I

• Enrolment Statistics (Spring 2021, recent)
  
• Permalink: https://is.muni.cz/course/pharm/spring2021/FAFO2_13