C9531 Structure of biomacromolecules

Faculty of Science
Autumn 2003
Extent and Intensity
0/1/0. 1 credit(s) (fasci plus compl plus > 4). Type of Completion: z (credit).
Teacher(s)
prof. Mgr. Lukáš Žídek, Ph.D. (seminar tutor)
Guaranteed by
prof. Mgr. Lukáš Žídek, Ph.D.
Chemistry Section – Faculty of Science
Contact Person: prof. Mgr. Lukáš Žídek, Ph.D.
Prerequisites
NOW( c9530 Structure of biomacromolecules )
The seminar is offered to students attending course C9530 (Structure of biomacromolecules).
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the seminar is to offer the chance to practice the knowledge acquired in course C9530 (Structure of biomacromolecules) and to prepare students for the exam of the course C9530.
Syllabus
  • 1. Structure of macromolecules, basic structural motifs of proteins and nucleic acids, structure of saccharides and membranes. 2. General characterization of proteins, methods of optical and mass spectroscopy, protein sequencing. 3. Nucleic acid sequencing, techniques of gene engineering, expression of recombinant proteins. 4-6. X-ray crystallography. Crystal preparation, diffraction experiment, methods of solving phase problem, electron density maps, structure model building. 7-9. Nuclear magnetic resonance. Isotope labeling, NMR experiment, spectral frequency assignment, determination of geometry (NOE, coupling constants), protein dynamics. 10-11. Molecular mechanics and dynamics, simulated annealing, experimental restraints. 12. Databases of structures, bioinformatics, computer prediction and modeling.
Language of instruction
Czech
Further Comments
The course is taught annually.
The course is taught: every week.
Teacher's information
http://www.ncbr.chemi.muni.cz/~lzidek/C9531.html
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2002, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.
  • Enrolment Statistics (Autumn 2003, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2003/C9531